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10 Cards in this Set
- Front
- Back
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Waxing waning illness; Anorexia; Depression/lethargy; Gastrointestinal signs; Response to symptomatic therapy; Crisis precipitated by stressful event |
hx features Hypoadrenocorticism |
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Depression/lethargy; Weakness; Dehydration / Shock; Hypothermia; Bradycardia; Melaena; Trembling/shaking; Abdominal pain; Often sicker than history suggests |
cs Hypoadrenocorticism |
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anaemia, erythrocytosis, lymphocytosisl eosinophilia - reverse stress leukogram; azotemia; hyperphosphatemia; hypoglycemia; hypoalbuminaemia |
lab features Hypoadrenocorticism |
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Hyperkalaemia Hyponatraemia Hypochloraemia Hypercalcaemia |
biochemical features Hypoadrenocorticism |
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Hyponatraemia and hyperkalaemia occur in other disease states -- how can you tell it is due to Hypoadrenocorticism? |
ratio < 23:1 |
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MegaoesophagusMicrocardiaReduced vasculatureMicrohepatica |
radiogrpaphical features Hypoadrenocorticism |
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in Hypoadrenocorticism US, left adrenal width - |
< 0.32 cm |
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Basal cortisol; Inject 250 υg ACTH; Sample 0.5-2 hours later - cortisol will peak |
ACTH response test |
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Parenteral Glucocorticoid only (Dex - No interference in cortisol assay; can be used prior to ACTH response test) Mineralocorticoid & glucocorticoid (Hydrocortisone - but Interferes with cortisol measurement) |
hormone replacement |
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Approximates aldosterone of 3000–3500 pmol/L 350 times mineralocorticoid activity of cortisolAs required for hyperkalaemia Use a dose of 0.5 - 0.625 mg/kg/hour |
hydrocortisone |
