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8 Cards in this Set
- Front
- Back
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Autoimmunity means:
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against it's own cells. Body perceives own cells as foreign.
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Immune hypersensitivity means:
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exaggerated and inappropriate
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Type I hypersensitivity:
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IgE–mediated allergic reactions
(allergy/anaphylaxis) |
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Type II hypersensitivity:
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Tissue-specific
(Blood transfusion reaction) |
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Type III hypersensitivity:
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Immune-complex mediated reactions
(AG-AB complexes form and deposit in tissues) |
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Type IV hypersensitivity:
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Cell-mediated reactions
(involves t-cells ; macrophages). |
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Systemic Lupus Erythematosus is
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A type III hypersensitivity
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List the 5 steps of patho in Systemic Lupus Erythematosus:
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1. B-cell secretes igG - attacks cells of the vessel walls.
2. T-helper cells stimulates more iGg 3. Magrophages start attacking cells of the vessel walls. 4. iGg attacks RBCs (causes anemia) 5. T suppressor cells become ineffective. |
