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13 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Pollen exposure causes this kind of hypersensitivity
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Type I
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This type of hypersensitivity is the fastest in onset
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Type I. Why is it so fast?
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Antibodies are already formedd.
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This kind of reaction involves antibody recognition of self or self antigen complexes
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Type II. Examples
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Autoimmune TTP., Erythroblastosis Fatalis, Graves, ANCA, Good Pasteur's, bullaeus pamphigus vulgaris
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Antigen is not bound to cell surface but antibodies recognize
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Type III. Example
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Henoch-Schonlein Purpura
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Immune Complex Disease
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Type III
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Antibody and Antigen are present in equal amounts
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Type III
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Involves IGM or IgG
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Type III.
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This type is said to be delayed and take 2 to 3 days
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Type IV
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MHC mediated hypersensitivity
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Type IV
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This type is said to be cell mediated and is the only cell mediated form. (CD8)
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Type IV. What are the cell mediated diseases?
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DM Type I(Insulin), MS(myelin basic), RA, Crohn's, Mantoux Tuberculin, Graft vs. Host, Hoshimoto's
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How does the Mantoux Tuberculin test work.
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The person does not have antibodes because is an intracellular(bacterial) antigen and must be presented. Time it takes has to do with presentation.
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Which hypersensitivities have compliment dependent actions?
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Type II. IgG or IgM activated complement via classical pathway--> MAC. Type III also. by what mechanism?
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An example is Farmer's lung with its Arthus reaction. Person is exposed, antibodies are made, next exposure leads to complexes which lodge in lung and fix C5a the neutrokine.
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Type II compliment independent reactions lead to what?
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IgG or IgE where in leukocytes lyse but do not phagocytize cells.
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