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Etiology

An elevated level of lipid in the blood causes plaque build-up along arterial walls

Risk factors

Obesity, high lipid diet, physical inactivity, FHx, DM, EtOH use

CC

Asymptomatic

Dx by

Typically diagnosed during routine blood work


Fasting blood work measuring cholesterol and triglyceride levels (elevated LDL)

HDL

High density lipoprotein


Removes cholesterol from artery plaques and recycles it back to the liver


"Good cholesterol"

Don't confuse with HLD

LDL

Low density lipoprotein


Transports cholesterol to arterial walls and aides formation of plaques


"Bad cholesterol"

HLD causes...

Arterial atherosclerosis - accumulation of cholesterol in blood vessels causes thickening/hardening of walls


CAD/MI - atherosclerosis of coronary arteries leads to acute MI


CVA/TIA - atherosclerosis of carotid artery can lead to carotid stenosis (narrowing) leading to CVA/TIA


Pancreatitis - FFA's in blood can damage pancreatic cells leading to inflammation

Non-pharmacological management

Decrease EtOH intake


Lose weight


CLOSE f/u (remember CC is asymptomatic)


Exercise


Change diet - avoid cholesterol, high fiber, high omega 3

Pharmacological management

Any medication ending in "-statin" - inhibits production of cholesterol; common brand names include Lipitor, Zocor, Crestor

NA

NA