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13 Cards in this Set
- Front
- Back
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LDL Goals for Lipid Management
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LDL<100 2+ risk factors
LDL<130 1-2 risk factors LDL<160 0-1 risk factors |
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HDL Goals
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>40 men
>50 women >60 is a negative risk factor |
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Total cholesterol goals
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<200 for most
>240 is high |
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Triglycerides
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<150 normal
200-499 high >500 dangerously high *priority for tx |
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Friederwald equation for calculating LDL
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LDL= TC - (HDL + TG/5)
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ATP III
NCEP |
Adult treatment panel III
National Cholesterol Educational Program |
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Familial hypercholesterolemia (FH)
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LDL= 250-450
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Polygenic Hypercholesterolemia (most common)
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LDL= 160-250
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Combined hyperlipidemias
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LDL= 160-250 and TGL= 200-800
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Drugs that elevate lipids
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BB, thiazides, BCP, oral estrogens, glucocorticoids, cyclosporines
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Statins
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Competitively inhibit HMGCoA reductase
upregulated LDL receptors, increase clearance of LDL and VLDL, increase HDL and lower TGL |
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Bile acid sequestrants (BAS or resins)
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Nonabsorbable anion exchange chloride ions for bile acids and other anions in the gi tract. Inhibits enterohepatic recycling. LDL receptors are upregulated
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Niacin
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Decreases VLDL senthesis leading to decrease LDL and TGL
inhibits apolipoprotein A1 which increases HDL |
