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7 Cards in this Set

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Normal Pressure Hydrocephalus is typically characterized by what symptoms?
The Three W's: Wet (incontinence), Wobbly (gait disturbance) and Wild (dementia).
The neuropathology of Normal Pressure Hydrocephalus involves
verntricular enlargement with associated
a) white matter damage (compresses blood vessels and decreases blood flow) and
b) compression of grey matter.
Normal Pressure Hydrocephalus treatment involves
Ventricular shunt (20% to 80% success rate)
a) External ventricular drain
b) Ventriculoperitoneal shunt
c) Third ventriculostomy (perforations in floor of 3rd ventricle allowing CSF to drain into the interpenduncular cistern).
Three causes of Hydrocephalus
1) Excess CSF
2) Obstruction of CSF flow
3) Decreased CSF absorption
Two categories of hydrocephalus
1) communicating -excess of CSF (rare), decreased re-absorption in arachnoid granulations, or obstruction of flow in subarachnoid space

2) noncommunicating-obstruction of flow of CSF
Symptoms of hydrocephalus include
*nausea
*headache (can be worse in morning)
*vomiting
*cognitive impairment
*decreased level of consciousness
*papilledema
*cognitive dysfunction, decreased vision
*sixth nerve palsies, *unsteady magnetic gait (feet barely leave floor)
*incontinence.
Eye movement abnormalities associated with hydrocephalus
1) Early stage: sixth nerve palsy-one or both eyes (incomplete or slow abduction of eye in horizontal direction.

2) More severe: inward deviation of one or both eyes.

3) Perinaud's syndrome: Limited upward gaze in the vertical direction.

4) In children: "Setting sun" sign: bilateral deviation of eyes downward and inward.