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193 Cards in this Set

  • Front
  • Back
How many vertebrae?
33
Cervical?
7
Thoracic?
12
Lumbar
5
Sacral
5
Primary curves
thoracic and sacral
Secondary curves
cervical and lumbar
Kyphosis
exaggeration of THORACIC curvature that may occur in elderly persons as a result of osteoporosis or disk degeneration
Lordosis
exaggeration of LUMBAR curvature that may be temporary and occurs as a result of pregnancy, spondylolisthesis, potbelly
Scoliosis
complex lateral deviation or torsion that is caused by poliomyelitis, a leg-length discrepancy or hip disease
Altanto-occipital joints
nodding head
between C1 (atlas) and occipital condyles
synovial joints and have no IV disk
anterior and posterior altanto-occipital membranes limit excessive mvmt at joint
Atlanto-axial joints
turn head side to side
between C1 and C2
synovial joints and have NO IV disk
alar joints limit excessive mvmt at joint
Atlanto-axis disolocation
tearing of transverse (cruciform) ligament bc of trauma or RA
to move within vertebral vanal
mobility contributes to risk of injury to cervical spinal cord and medulla leading to sudden death
inflammatory osteoarthritis affects lumbar and sacroiliac joint
annulus fibrosus of IV disks may become ossideid
bamboo spine
most are positive for HLA-b28
ankylosing spondylitis
fish mouth vertebra
central depression in vertebral body
sickle cell anemia
pedicles of lumbar vertebra degenerate or do not dev properly
body of lumbar vertebra moves anterior w/ respect to vertebrae below it
causes lordosis
spondylolisthesis

degenerative - L4-5
congenital - L5-S1
hemivertebrae
portion of vertebral body does not develop
occurs in scoliosis
breast lung prostate cancers metastasize to brain bc
internal vertebral venous plexus, basivertebral veins, external vertebral venous plexus that surround vertebral column communicate w/ cranial dural sinuses and veins of thorax, abdomen, pelvis
C4 landmark
hyoid bone
bifurcation of common carotid artery
C5 landmark
thyroid cartilage
carotid pulse palpated
C6
cricoid cartilage
start of trachea
start of esophagus
T2
sternal notch
arch of aorta
T4
sternal angle
junction of superior and inferior mediastinum
bifurcation of trachea
T5-T7
pulmonary hilum
T8
IVC hiatus
T10
esophageal hiatus
T12
aortic hiatus
L1
superior mesenteric artery
upper pole of right kidney
end of spinal cord in adult (conus medullaris) and pia mater
L2
renal artery
L3
end of spinal cord in newborn inferior mesenteric artery
umbilicus
L4
iliac crest
bifurcation of aorta
S1
sacral promontory
start of sigmoid colon
S2
end of dural sac, dura, arachnoid, subarachnoid space, CSF
S3
end of sigmoid colon
C4-C5 disk herniation
compressed nerve root is C5
shoulder and lateral surface of upper limb (dermatome)

muscle: deltoid

mvmt weak: abduction of arm

nerve and reflex involved: axillary nerve, decr biceps jerk
C5-C6 disk herniation
C6 compressed
thumb dermatome affected

weak muscles: bicpes brachialis brachioradialis

weak mvmt: flexion of arm, supination or pronation

nerve reflex: musculocut nerve, decr biceps jerk, decr brachioradialis jerk
C6-C7 disk herniation
C7 compression
posterior surface of upper limb
middle and index fingers

mm: triceps, wrist extensors

mvmt weakness: extension of forearm and wrist

nerve/reflex: radial nerve, decr tricep jerk
L3-L4 disk herniation
L4 medial surface of leg and big toe

mm: quadriceps

mm weakness: extension of knee

nerve/reflex: femoral nerve/ decr knee jerk
L4-L5 disk herniation
L5 lateral surface of leg
dorsum of foot

affected mm: tibialis anterior, extensor hallucis longus,extensor digiti minimi

mvmt: dorseflexion, extension of toes, eversion of foot

Nerve/reflex: common peroneal, knee jerk
L5-S1 disk herniation
S1 posterior surface of lower limb
little toe (gastrocnemius and soleus)

plantar flexion of ankle/flexion of toe

Tibial nerve
decr ankle jerk
teardrop fracture
Hyperflexion of cervical region
spinal cord at risk
tears posterior longitudinal ligament
hangman fracture
hyperextension of cervical region
tears anterior longitudinal ligament
jefferson fracture
compression of cervical region
tears transverse ligament
thoracolumbar column trauma
hyperflexion of thoracic or lumbar region
gray matter of spinal cord consists of neuronal cell bodies
divided into
dorsal horn
ventral horn
lateral horn
white matter consists of
neuronal fibers
divided into dorsal funiculus, ventral funiculus, lateral funiculus
conus medullaris
end of spinal cord
L1 in adults
L3 in newborn
cauda equina
dorsal and ventral nerve roots of spinal nerves L2 through coccygeal 1
nerve roots travel in subarachnoid space below conus medullaris
filum terminale
extension of pia mater that reaches from conus medullaris to end of dural sac at vertebral level S2 where it joins dura
dura continues caudally as filum of dura mater which attaches to the dorsum of the coccygeal bone
epidural space
contains fat and internal vertebal venous plexus
located between vertebrae and dura mater
dura mater
tough, outermost layer of meninges
subdural space
located btwn dura and arachnoid
arachnoid
filmlike transparent layer that connected to pia mater by trabeculations
subarachnoid space is located between
arachnoid and pia
filled w/ CSF
pia mater
pia mater is a thin layer that adheres closely to spinal cord
lateral extensions (denticulate ligaments) attach to dura mater thereby suspending spinal cord w/i dural sac
anterior spinal artery
arises from vertebral arteries
supply ventral 2/3 of spinal cord
posterior spinal arteries
2 posterior spinal arteries that arise from vertebral arteries of posterior inferior cerebellar arties
supply dorsal 1/3 of spinal cord
radicular arteries
arise from vertebral, deep vervical, ascending cervical posterior intervostal, lumbar, lateral sacral
enter vertebral canal through IV Foramina and br into anterior and posterior radicular arteries
Great radicular artery
arises from left side from posterior interocostal artery
important contribution to anterior spinal artery
provides main blood supply to lower part of spinal cord
ligation of great radicular artery during resection of abdominal aneurysm resulted in anterior spinal artery syndrome
anterior spinal artery syndrome
paraplegia
impotence
loss of voluntary control of bladder and bowerl incontinence
loss of pain and temp sensation
lumbar puncture
the needle passes through
skin --> superficial fascia --> supraspinatus --> interspinous ligament --> ligamentum flavum --> epidural space containing internal vertebral venous plexus --> dura mater --> arachnoid --> subarachnoid space containing CSF
dimpling in breast cancer due to
suspensory ligament shortening
if breast cancer invades RETROMEMMARY SPACE
contraction of pec major may cause whole breast to move superiorly
glandular tissue within breast is a modified sweat gland consisting of acini
acini are drained by 15-20 lactiferous ducts
each lactiferous duct expands into lactiferous sinus which serves as
a reservoir for milk during lactation
chief venous drainage is to
axillay vein
internal thoracic, lateral thoracic, intercostal veins

breast cancer may metastasize to brain by following routes: cancer cells enter an intercostal vein --> external vertebral venous plexus --> internal vertebral venous plexus --> cranial dural sinuses
nipple secretion
contains exfoliated duct cells, alpha-lactalbumin, immunoglobulins, lactose, cholesterol, steroids, fatty acids
along w/ ethanol, caffeine, nictoine, barbs, pesticides, techentium
nipple discharge
benign cause typically green, milky yellow or brown is bilateral
not spontaneous and affects mult ducts

milky discharge is acc by headache and loss of peripheral vision may indicate a pituitary adenoma

nipple discharge from a malignant cause typically is bloody or clear, unilateral, spontaneous affects a single duct
fibroadenoma
benign proliferation of CT in which mammary glands are compressed into cords of epihtelium
sharply circumscribed, spherical nodules that moves freely
infiltrating ductal carcinoma
malignant proliferation of duct epithelium in which tumor cells are arranged in cell nests, cords, anastomosing masses
MOST COMMON type of breast cancer accounting for 65-80% of all cases
pleuritis - visceral
no pain
the visceral pleura receives no nerve fibers of general sensation
parietal pleura causes
sharp local pain and referred pain
innervated by intercostal nerves and phrenic nerve C3-5
pain may be referred to thoracic wall and root of neck respectively
pleura may be damaged inadvertently
posterior surgical approach to kidney
abdominal incision at right infrasternal angle
stellate ganglion nerve block
brachial plexus nerve block
knife wound to chest wall above clavicle
fracture of lower ribs
malignant mesothelioma
most serious pleural neoplasm
history of asbestos exposure increases risk of malignancy
spontaneous pneumothorax
air enters pleural cavity
ruptured BLEB of diseased lung that result in negative pressure and collapsed lung
chest pain, cough, mild to severe dyspnea
open pneumothorax
parietal pleura is pierced and pleural cavity is opened to outside atmosphere
on inspiration, air is sucked into pleural cavity
lung collapses
common causes: chest trauma, iatrogenic factors
tension pneumothorax
occur as a sequeal to open pneumothorax if inspired air cannot leave pleural cavity through wound on expiration
results in collapsed lung on wounded side and compressed lung on opposite side due to a deflected mediastinum

CP, SOB,m absent breath sounds on affected side, hypotension, mediastinal shift compresses SVC, IVC, --> obstructing venous return
cricoid cartilage vertebral level
C6 and ends at sternal angle T4
where it bifurcates into right and left main bronchi
carina
on bronchoscopy
last tracheal cartilage
compression of trachea
may be compressed by either an enlarged thyroid gland or an aortic arch aneurysm
aneurysm may tug on trachea w/ each cardiac systole
can be felt by palpating trachea at sternal notch vertebral level T2
distortions in position of carina
indicate mets of bronchogenic carcinoma into tracheobronchial LN that surround the tracheal bifurcation or enlargement of LA
aspiration of foreign objects
aspirated material enters different parts of lung
dependong on person's position at time of aspiration
sitting or standing aspiration
aspirated material enters RIGHT LOWER LOBAR bronchus and lodges within lower portion of right lower lobe
supine - aspiration
aspirated material enters RIGHT LOWER LOBAR BRONCHUS
lodges w/i UPPER PORTION OF RIGHT LOWER LOBE
lying on right side
right upper lobar bronchus
within posterior portion of right upper lobe
lying on left side
left upper lobar bronchus
within lingula of left upper lobe
common peroneal
trauma to the lateral aspect of leg or fibula neck fracture

motor def: foot eversion, dorseflexion, toe extension

sensory def: anterolateral leg and dorsal aspect of foot
tibial
knee trauma

motor def: foot inverion, plantar flexion, toe flexion

sensory def: sole of foot
superior gluteal
posterior hip dislocation or polio

motor def: Positive Trendenlenberg sign, thigh abduction
obturator
anterior hip dislocation

motor def: adduction of thigh

sensory: medial thigh
inferior gluteal
posterior hip dislocation

motor def: cant jump, climb stairs or rise from seat
how is axillary nerve lesioned?
surgical neck fracture
dislocation of humerus
dislocation of humerus
intramuscular injections
how is radial nerve injured?
spiral groove
lesioned by midshaft fracture of humerus

compressed in axilla by incorrect use of crutch
how is C7 compressed?
compressed by cervical disk lesion
how is lower trunk of brachial plexus injured?
Klumpke's palsy or pancoast tumor
compressed by cervical rib
how is median nerve injured?
compressed by supracondylar fracture of humerus
pronator teres syndrome
how is medial nerve compressed distally?
compressed in carpal tunnel syndrome
DISLOCATED LUNATE!
how is anterior interosseous compressed?
in deep forearm
it is a branch of median nerve
how is recurrent br of median n injured?
lesion by superficial laceration
how is ulnar nerve lesioned?
repeated minor trauma
fracture of medial epicondyl of humerus

lersion by trauma of heel of hand, fracture of HOOK OF HAMATE
scaphoid fracture can lead to what?
injury of radial artery
brachial plexus
Roots
Trunks
Divisions
Cords
Branches

Randy Travis Drinks Cold Beer
Clavicle fracture
relatively common - brachial plexus is protected from injury by subclavius muscle
musculocutaneous nerve
C5-C7
upper trunk compression
motor def; flexion of arm at elbow
sensory: lateral forearm
Ulnar nerve
C8-T1
PROX: fracture of medial epicondyle
DISTAL: fracture of hook of hamate (falling onto outstretched hand)

Motor def: medial finger flexion, wrist flexion, abduction/adduction of fingers (interossei), adduction of thumb, extension of 4th and 5th fingers (lumbricals)

sensory: medial 1.5 fingers, hypothenar eminence

sign: radial deviation of wrist upon wrist flexion

Pope's blessing, hand of benefiction
Median nerve
C6-C8, T1

prox: fracture of supracondylar humerus
distal: carpal tunnel syndrome, dislocate LUNATE

motor def: opposition of thumb, lateral finger flexion, wrist flexion
dorsal and palmar aspect of lateral 3.5 fingers, thenar eminence
dorsal and palmar aspects of lateral 3.5 fingers

sign: ape hand, ulnar deviation of wrist upon wrist flexion
radial nerve
C5-C8
fracture of midshaft of humerus
Sat. night palsy
extended compression of axilla by back of chair or crutches

motor def: wrist extension, finger extension at MCP joints
supination
thumb extension abd abduction

sensory def: posterior arm, dorsal hand and thumb
sign: wrist drop
axillary
C5, C6

fractured surgical neck of humerus, dislocation of humeral head
motor: arm abduction at shoulder
sensory def: over deltoid muscle

sign: flattened deltoid
paracentesis
needls is inserted through layer of abdominal wall to w/d excess peritoneal fluid (knife wounds to abdomen penetrate layers of abdominal wall)

Midline approach: tinea alba --> transversalis fascia --> extraperitoneal fat --> parietal peritoneum

flank approach: skin --> superficial fascia, --> external oblique muscle, internal oblique muscle --> transversus abdominis, trasversalis fascia --> extraperitoneal fat
inguinal region
weak area in anterior abdominal wall bc it is where testes and spermatic cord or round ligament of uterus penetrates during embryologic development
surgical hernia repair may damage
iliohypogastric nerve --> anesthesia of ipsilateral abdominal wall and inguinal region
ilioginguinal nerve --> anesthesia of ipsilateral penis, scortum, medial thigh
scrotum
outpoutching of lower abdominal wall where by layers of abdominal wall continue into scrotal area to cover spermatic cord and testis
Cyptorchidism
testis fails to descend into scrotum
usually occur at 3 months
undescended testis may be found w/i inguinal canal or abdominal cavity
bilateral cryptorchidism results in sterility
hydrocele
small patency of processus vaginalis remains from embryologic dev
peritoneal fluid than can flow into processus vaginalis creating a gluid-filled cyst
scrotum cancer mets to
superficial inguinal nodes
tests mets to
deep lumbar nodes near renal hilus
also called para-aortic
extravasated urine occurs due to what injury?
saddle injury
leaking into superficial perineal space located between colles fascia and dartos muscle and external spermatic fascia
vasectomy
skin --> colles fascia and dartos --> external spermatic fascia --> cremasteric fascia and muscle --> internal spermatic fascia --> extraperitoneal fat

tunica vaginalis is not cut
Direct inguinal hernia
protruydes directly through anterior abdominal wall within Hasselbach triangle
(laterlly bound by inferior epigastric artery and vein, medially by rectus abdominis, inferiorly by inguinal ligament
common in OLDER males, rare in women

mass in inguinal region that protrudes on straining and disappears at rest, constipation, prostate enlargement
hernia can be detected w/ pulp of finger
indirect inguinal hernia
protrudes through deep inguinal ring to enter inguinal canal
may exit through superficial inguinal ring into scrotum
protrudes lateral to inferior epigastric artery and vein
protrudes above and medial to pubic tubercle
common in young males
more common than direct inguina hernia
clinical signs: tender, painful mass in inguinal region that continues to scrotum
hernia can be felt w/ type of finger
femoral hernia
protrudes thr femoral canal below inguinal ligament
below and lateral to pubic tubercle
medial to femoral vein
more common in females
appears on right
early strangulation
layers of abdominal wall --> testes and spermatic cord coverings
skin--> skin
superficial fascia --> colles and dartos muscle
superficial space (etxtravasated urine)
external oblique --> external spermatic fascia
internal oblique --> cremasteric fascia and muscle
transverse abdominus does not continue into scrotal area
transveralis fascia --. internal spermatic fascia
extraperitoneal fat --> extraperitoneal fat
parietal paritoneum --> tunica vaginalis
peritoneal cavity
potential space between visceral peritoneum
divided into lesser and greater peritoneal sacs
omental foramen of Winslow
opening of connection btwn lesser and greater peritoneal sacs
if surgeon places a finger in omental foramen, IVC lies posterior and portal vein lies anterior to his or her finger
omentum - lesser
fold of peritoneum that extends from the porta hepatis of liver to lesser curvature
consists of hepatoduodenal ligament and hepatogastric lligament
portal tried lies in the free margin of hepatoduodenal ligament
intraperitoneal organs
stomach
part 1 of duodenum
jejunum
ileum
cecum
appendix
transverse colon
sigmoid colon
liver
gallbaldder
tail of pancreas
spleen
Celiac artery supplies
foregut
at T12 to the first part of duodeum
superior mesenteric artery
supplied midgut at L1 up to proximal 2/3 of trasverse colon
inferior mesenteric
located at vertebral level L3 supplies viscera that derive embryologically from hindgut, distal 1/3 of transverse colon --> upper portion of rectum
abdominal aortic aneurysm
below L1
most common site of rupture is left posteriolaterla wall
immediate cpmpression of aorta gainst vertebral bodies above celia trunk
left renal vein is put in jeaopardy
inferior mesenteric lies in middle of AAA
sudden onset of sever central abdominal pain may radiate to back
pulsatile tender abdominal mass and hypotension, delirium
ischemic colitis is result of ligation of inferior mesenteric
spinal ischemia due to ligation of greater radicular artery
acute mesenteric ischemia most commonly caused by
superior mesenteric artery

severe abdominal pain that is out of proportion to physical findings
no evidence of peritonitis
acute mesenteric ischemia usually occurs inelderly pts
right gonadal vein vs left
right gonadal drains directly into IVC
left gonala vein drains into left renal vein
in a woman, right sided hydronephrosis may indicate
thrombosis of right ovarian vein which would constrict ureter b/c right ovarian vein crosses vein crosses ureter to drain into IVC
in a man: left sided testicular varicocele may indicate occlusion of
left testicular vein or left renal vein by malignant tumor of kidney
Esophagus varices
Portal: Left gastric vein
Systemic: esophageal vein
Caput medusa
portal: paraumbilical vein
IVC: superficial and inferior episgastric vein
rectal hemorroids
Portal: superior rectal
systemic: middle and inferior rectal veins
is splenic vein systemic or portal?
portal
portal hypertension results in
vomiting copious amounts of blood, history of alcoholis, liver cirrhosis, schistosomiasis, enlarged abdomen as a result of fluid and splenomegaly
esophageal cancer (adenocarcinoma) metastasize below diaphragm to
CELIAC LN
bronchogeni carcinoma may indent esophagus as a result of enlarged...
MEDIASTINAL LN
forceful vomiting due to alcoholism, bulimia, pregnancy -->
retroperitoneal pain after vmiting and extravasated contrast medium

Mallory-Weiss tears involved only mucosal and submucosal layers

Boerhaave syndrome tears through all layers of esophagus
sliding hiatal hernia
stomach herniates through diaphragm into thorax
deep burning retrosternal pain
reflux of gastric content (bitter taste?)
paraesophageal hiatal hernia
only stomach herniates through
no reflux of gastric contents
strangulation of obstruction may occur
achalasia
failure of LES to relax during swallowing
b/c of absence of MYENTERIC plexus
progressive dysphagia (difficult swallowing)
barium swallow shows dilated esophagus above LES
CHAGAS disease may lead to achalasia
esophageal reflux
dysfunction of LES allows gastric acid to reenter lower esophagus
substernal pain and heartburn
may worsen w/ bending or lying down
esophageal strictures (narrowing)
caustic strictures are result of injury caused by ingestion of vaustric agents
mucosal destruction due to gastric reflux
barrett esophagus
replacement of stratified sq epithelium w/ gastric epithelium
may lead to esophageal adenocarcinoma
general feature of stomach
muscular organ that functions in food digestion and storage
divided into 4 parts:
CARDIA
FUNDUS
BODY
ANTRUM
gastric ulcers occur in
body along lesser curvature
predominantly PARIETAL cells
caused by damage to mucosal barrier
result of smoking, excessive salicylate ingestion, NSAIDs
70% assoc w/ H pylori
BURNING PAIN increases after meal (lose weight)
hypertrophic pyloric stenosis
congenital conditions that present w/i weeks of birth
PROJECTILE vomiting, no bile, visible PERISTALSIS, hard,mobile mass palpated on epigastric region
dumping syndrome
abnormally rapid emptying of hyperosmotic stomach contents
occurs after partial gastrectomy or vagotomy
performed to treat an ulcer or obesity

clinical findings: epigastric dicomfort, rumbling sounds caused by gas movement, palpitations, dizziness, diarrhea, hypoglycemia
where does the stomach metastasize to?
supraclavicular Lymph nodes (VIRCHOW nodes) on left side
can be palpated w/i posterior triangle of neck
Duodenum - superior part
intraperiotenal begins at pyloris of stomach
duodenal cap or bulb
descending part of duodenum is retroperitoneal, receives common bile duct and main pancreatic duct via
ampulla of Vater
horixontal part is retroperitoneal, at vertebrae
L3 between superior mesenteric anterior and aorta and iVC posterior
ascending part
intraperiteonal and ascends to meet jejunum at duodenojejunal flexure which supported by ligament of treitz (cranial end of dorsal mesentery)
perforation of duodenum anterior or posterior would cause severe hemorrhage?
posterior b/c it erods into gastroduodenal artery
duodenal ulcer
most often in superior part
damage to mucosal barrier and hypersecretion of gastric acid
100% pts have assoc H pylori
severe epigastric pain DECR after meal

tx: H2 receptor antagonists, antacids, sucralfate, bismuth, omeprazole, Bismuth, metronidazole, tetracycline
celiac disease
hypersensitivity to gluten and gliadin protein
found in wheat and grains
contribute to immunologic damage to mucosa
GLIADIN antibodies detectable in blood
chronic diarrhea, flatulence, weight lloss and fatigue
where is the sight of B12 absorption?
ileum
where are their Peyer patches?
ileum
where are there teniae coli
large intestines
three longitudinal bands of SM
also have fatty tags and haustra
where is there long vasa recta?
jejunum
what is the main site of absorption?
jejunum
thicker wall, more vascular, redder than illeum
long finger-shaped villi
where are there crypts and no villi?
large intestines
chronic granulomatous inflammatory bowel disease that most commonly affects ileum
ulcers can coalesce to serpentine ulcers
classic features is clear demarcation of iseased bowel
skip areas
mass in right lower quadrant, diarrhea, fever, weight loss, weakness
strictures of intestinal lumen and formation of fistulas
CROHN
appendicitis
initial pain in umbilical and epigastric region
right lumbar region, N/V, anorexia, tenderness to palpation and percussion

McBurney point is located by drawing a line from right anterior superior iliac spine to umbilicus
toxic megacolon
dilation of transverse colon that results in perforation of colonic wall
clinical signs include: abdominal pain, fever, leukocytosis
bile
what does it contain?
produced primarily by hepatocytes at average rate of 600 ml/day
primarily: water, electrolytes, bilirubin glucoronide, cholic acid, chenodeoxycholic acid conjugated to glycine or taurine, cholesterol, lecithin, Ca2+, secretory IgA
liver biopsies - where?
needle puncture through right intercostal space 8-10
skin --> superficial fascia --> external oblique muscle --> intercostal muscle --> costal parietal pleura --> costodiaphramatic recess --> diaphragmatic parietal pleura --> diaphragm --> peritoneum
affects dev of intrahepatic and extrahepatic bile ducts
presents w/i weeks of birth
most common cause of persistent jaundice in infancy
dark urine
clay-colored stools
bile duct proliferation w/ dilation of bile canaliculi and bile plugs
congenital biliary atresia
granulomatous destruction of medium-sized intrahepatic bild ducts
cirrhosis appears later in course of disease
characterized by antimitochondrial autoantibodies
primary biliary cirrhosis
inflammation, fibrosis, and segmental dilation of intrahepatic and extraheptic bile ducts
occurs in assoc w/ chronic UC
right hypochondriac region pain, painless jaundice, no fever or chills, pruritis, fatigue, nausea
primary sclerosing cholangitis
uncinate process develops from:
ventral pancreatic bud
head of pancreas dev from
ventral pancreatic and dorsal bud
lies in duodenal C-loop
pancreatic neck is from
dorsal pancreatic bud
lies at confluence of inferior mesenteric and splenic vein
body and tail dev from
dorsal pancreatic bud
annular pancreas occurs when
ventral pancreatic bud fuses w/ dorsal pancreatic bud both dorsally and ventrally forming a ring
causes obstruction of duodenum shortly after birth
what develops from ventral pancreatic bud?
uncinate process and head
acute pancreatitis
assoc w/ biliary tract disease or alcoholism

pain in epigastric region radiates to back
nause,vomiting
elevated amylase lipase
retroperitonela hemorrhage --> flank ecchymosis (turner sign ) or periumbilica ecchymosis (cullen sign)
pancreatic adenocarcinoma
very aggressive
poor prognosis
radiates to back, weight loss, obstructive jaundice
whipple
remove head of pancreas, dudoenum, distal common bile duct, fallbladder and distal stomach
what is the primary function of sigmoid colon?
store feces
goes from S1-S3
diverticulosis
presence of diverticular
most commonly found in sigmoid colon >60 yo
diverticulitis
pain in left lumbar region
palpable inflammatory mass
fever leukocytosis ileus peritonitis
flexible sigmoidoscopy
large intestine may be puctured
bends in anterior direction and to left
colostomy
sigmoid colon often used in colostomy
Gardner syndrome
variation of FAP characterized by adenomatous polups and mult osteomas
Turcot syndrome
variation of FAP in pts have adenomatous polyp and gliomas
FAP
is archetype of adenomatous poluyposis
rectosigmoid colon
irregular in shape, sessile, more than 2 cm in diameter
AD
mutation in APC nationcogene
progression from small to large polyp is ras
progression from large polyp to carcinoma w/ mutations in DCC and p53
protrusion of full thickness of rectum through anus
bowel protruding through anus, bleeding, anal pain, mucous discharge, anal incontinence caused by strethcing of internal and external anal sphincters
stretch injury of pudendal nerve
above pectinate line
columnar or cuboidal
portal venous system
internal iliac nodes
visceral sensory
internal hemorroids
below pectinate line
stratified sq
caval venous system
superficial inguinal nodes
somatic sensory
external hemorroids