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31 Cards in this Set
- Front
- Back
Differentiation
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Cell specialization during development
-Occurs not by modification of DNA but rather by the determination of which parts of DNA are actually used by that cell |
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Embryonic Stem Cell
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cell that has differentiated and will give rise to a population of specialized cells during further development
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Meiosis produces what type of cell
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Haploid
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Metacentric
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The centromere near the middle of the two chromatids
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Submetacentric
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centromere displaced to one end of chromatids
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acrocentric
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Centromere near the very ends of the chromatids
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"p" chromatid arms
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the short arms
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"q" chromatid arms
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longer arms
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Locus
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physical location on a chromosome
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Replication
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Can only occur on a single strand of DNA
under the control of the enzyme DNA polymerase |
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Transcription
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The production of RNA from one of the paired chains of DNA
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How does RNA differ from DNA?
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1.) The sugar in the sugar-phosphate backbone has a hydroxyl group that is missing from deoxyribose - thus is it Ribose
2.)RNA single stranded and does not form a double helix 3.)thymine of DNA is replaced by uracil in RNA |
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Transfer RNA (tRNA)
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transfer amino acids to the protein chain
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Ribosomal RNA
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found in the ribosome, function in the translation of RNA in proteins
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messenger RNA (mRNA)
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serve as templates for the production of proteins from individual amino acids
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Translation
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after the mRNA has been properly edited it will be translated into a protein
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Silent Mutations
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mutations with no phenotypic effects
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Reading frame shift
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cause a shift of the genetic code and will be mistranslated
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Robertsonian Translocation
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two nonhomologous acrocentric chromosomes fuse such that their short arms are lost and their long arms make up the p and q arms --down syndrom
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nondisjunction
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homologous pairs do not separate from one another at the first meiotic division
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Mendel's first law
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Segregation of alleles: 2 alleles at a locus segregate when gametes are formed
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Mendel's second law
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Independent Assortment of Alleles: alleles at different loci segregate independently of one another
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mitochondrial DNA
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short stretch of DNA that forms a continuous circle and is found only in the mitochondria
typically only transmitted from mothers |
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Probability Theory
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way of measuring the frequency with which events will occur
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Pleiotropic effect
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one gene that has an effect on many things
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polygentic
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many genes that have an effect on one structure
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Hardy-Weinburg equilibrium
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states that both allele and genotype frequencies in a population remain constant—that is, they are in equilibrium—from generation to generation unless specific disturbing influences are introduced.
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Natural Selection
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Phenotypic variation - more or less successful
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Genetic Drifts
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Founders effect, bottle neck
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Gene Flow
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migration of people of organisms has an allele
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ABO blood group
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discovered by Landsteiner in 1900
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