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31 Cards in this Set

  • Front
  • Back
Differentiation
Cell specialization during development

-Occurs not by modification of DNA but rather by the determination of which parts of DNA are actually used by that cell
Embryonic Stem Cell
cell that has differentiated and will give rise to a population of specialized cells during further development
Meiosis produces what type of cell
Haploid
Metacentric
The centromere near the middle of the two chromatids
Submetacentric
centromere displaced to one end of chromatids
acrocentric
Centromere near the very ends of the chromatids
"p" chromatid arms
the short arms
"q" chromatid arms
longer arms
Locus
physical location on a chromosome
Replication
Can only occur on a single strand of DNA

under the control of the enzyme DNA polymerase
Transcription
The production of RNA from one of the paired chains of DNA
How does RNA differ from DNA?
1.) The sugar in the sugar-phosphate backbone has a hydroxyl group that is missing from deoxyribose - thus is it Ribose

2.)RNA single stranded and does not form a double helix

3.)thymine of DNA is replaced by uracil in RNA
Transfer RNA (tRNA)
transfer amino acids to the protein chain
Ribosomal RNA
found in the ribosome, function in the translation of RNA in proteins
messenger RNA (mRNA)
serve as templates for the production of proteins from individual amino acids
Translation
after the mRNA has been properly edited it will be translated into a protein
Silent Mutations
mutations with no phenotypic effects
Reading frame shift
cause a shift of the genetic code and will be mistranslated
Robertsonian Translocation
two nonhomologous acrocentric chromosomes fuse such that their short arms are lost and their long arms make up the p and q arms --down syndrom
nondisjunction
homologous pairs do not separate from one another at the first meiotic division
Mendel's first law
Segregation of alleles: 2 alleles at a locus segregate when gametes are formed
Mendel's second law
Independent Assortment of Alleles: alleles at different loci segregate independently of one another
mitochondrial DNA
short stretch of DNA that forms a continuous circle and is found only in the mitochondria

typically only transmitted from mothers
Probability Theory
way of measuring the frequency with which events will occur
Pleiotropic effect
one gene that has an effect on many things
polygentic
many genes that have an effect on one structure
Hardy-Weinburg equilibrium
states that both allele and genotype frequencies in a population remain constant—that is, they are in equilibrium—from generation to generation unless specific disturbing influences are introduced.
Natural Selection
Phenotypic variation - more or less successful
Genetic Drifts
Founders effect, bottle neck
Gene Flow
migration of people of organisms has an allele
ABO blood group
discovered by Landsteiner in 1900