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41 Cards in this Set
- Front
- Back
draw out throxine pathway
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see endocrinology
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where is insulin made and where does it go to.
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insulin made by beta cells in pancrease -- it travels to muscles, liver, and adipose tissue
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where is glucagon produced and where does it go
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glucagon is produced by the alpha cells in the pancrease and it travels to the liver
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what two processes does glucagon promote
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glycogenolysis- breakdown glycogen and gluconeogenesis - make glucose from other sources
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what are the two main things that determine the amount of muscle tension
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1- number/ kind of motor units
2- frequency of action potentials |
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what is a comparison to an auxotonic type of muscle contraction? Also, in this type of contraction as muscle length decreases tension ______.
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BOW/ ARROW; increases
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What type of contraciton is characterized when muscle length decreases tension decreases.
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mietonic
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____ is a ancrease in the number of muscle cells?
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hyperplasia
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what is the starting compound for steroids and where does it originate?
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cholesterol-- in the liver
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_____ is a substance that is secreated via a ductless gland into the blood and binds with target cell receptors.
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hormone
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what are the advantages of having a multi level (long level) regulation
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back-up / fine tuning
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what is tyrisine (aa) convereted into?
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catecholamines- (dopamine, norepinephrine, epinephrine)
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what hormone is trytophan convereted into and where in brain does this happen
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melatonin in the pineal gland
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what are the three major classes of hormones
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1. amine hormones, peptide hormones, and steroids
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Amine hormones are all derived from what amino acid
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tyrosine
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what is the largest class of hormones
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peptide
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where is the breakdown site for proteinaceous hormones
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within the target cell
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what cells make glucagon
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alpha cells of pancrease
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what is the name for the structure that connects the hypothalmus to pituitary
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infundibulum
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what two hormones are stored in posterior pituitary
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vasopressin (ADH) and oxytocin
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what affect does vasopressin have in the kidneys
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It causes less water to be excreted in uring so that BP is higher
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what 2 ways does ADH raise bp?
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by causing less water to be excreted and by constricting blood vessels
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what all hormones are produced by anterior pituitary
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FLAT PEG - FSH, LH, ACTH, TSH, Prolactin, GH
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how do adrogens promote growth?
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they up regulate the GH receptors
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what is gluconeogenesis
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formation of glucose from non glucose sources: pyruvate, lactate, glycerol, or amino acids
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what are the secondary hormones besides GH that contributes to growth
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thyroxine, insulin, sex hormones
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what is the source of DHEA in the female
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the adrenal cortex
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how is GH like insulin
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it cuases cell to uptake a.a and to promotes protein synthesis
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How is GH different from insulin
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it inhibits uptake glucose from most areas, promotes lipolysis, promotes glycogenesis,
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what are the three areas of the adrenal cortex and what are the major hormones produced by each
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1) zona glomerulosa- catecholamines
2) zona fasciculata- cotisol and androgens 3) zona reticularis (redickularis)- androgens (cortisol). |
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as defined as a glucocorticoid what does cortisol do?
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It breaks down carbs, fats, and proteins
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As defined as a mineralcorticoid what does aldosterone do? When is aldosterone released and what effects does it cause?
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it maintain the balance of Na and K. It is released when bloodpressure is to low and it causes Na to enter blood and water follows and K leaves if your K level is too high.
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what two factors could cause aldosterone production?
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1) renin-angiotension system 2) elevated K levels
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list all of the functions of cortisol?
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1) break down carbs
2) hepatic gluconeogenesis- production of glucose from other sources besides glucogen 3) lipolysis 4) protein degradation (only cortisol can do this). 5) protein synthesis to repair injury. |
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How does melatonin directly block turmor growth?
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It blocks cancel cell's metabolism of linoleic acid
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how does melatonin indirectly block tumor growth?
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It prevents the ovary from producing high levels of estrogen and other sex hormones that can cause cancer in breasts
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what carrier protein is specific to cotisoll
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CBG
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what is the major breakdown site for steroids and what happens here
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the liver; large steroids are broken into smaller units and SO4 added to increase polarity
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what is the major excretion site for steroids
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kidneys and in feces as bile
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what hormone in the anterior pituitary is responsible for milk production
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prolactin
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what are all the effects of GH
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1) growth (major) of bone and muscle
2) metabolism (minor)- glycogenesis and lipolysis |