Human Physiology Skin Lab Ucf

Front 1

Neuroectoderm derived, melanin producing and transporting cells, located mainly on stratum spinosusm.

Back 1

melanocyte

Front 2

where are melanocytes mainly located?

What are they derived from?

Back 2

-stratum spinosum

-neuroectoderm

Front 3

RBM derived, star shaped cells located mainly in stratum spinosum. They  function  as APC’s  linking  the intergumentary system to immune.

Back 3

Langerhans cells

Front 4

Where are Langerhans cells derived?

Where are they mainly located?

Back 4

-RBC derived

-stratum spinosum

Front 5

In a keratinocyte keratine is a type of ________

Back 5

intermediate filament

Front 6

Mainly present in thick skin. They may function as tactile receptors and have been correlated to be part of difuse enteroendocrine system cells (DNES).

Back 6

Merkel Cell

Front 7

Where are merkel cells mainly present?

Function as?

Back 7

-thick skin

-tactile receptors

Front 8

composed of a single row of cuboidal or columnar keratinocutes that contain intermediate filaments?

Back 8

stratum basale

Front 9

8-10 rows of polyhedral keratinocytes.
cells are bound together by keratin bundles, tonofilaments

Back 9

stratum spinosum

Front 10

present only in the skin of fingertips, palms, soles.
3-5 rows of clear flat dead keratinocytes

Back 10

stratum lucidum

Front 11

25-30 rows of dead flat keratinocytes

Back 11

stratum corneum

Front 12

Yellow to reddish-brown to black, responsible for dark skin colors

Back 12

melanin

Front 13

Melanin is produced in _________; migrates to ___________ where it forms “pigment  shields”  for  nuclei

Back 13

-melanocytes

-keratinocytes

Front 14

What are freckles and moles?

Back 14

local accumulations of melanin

Front 15

Yellow to orange, most obvious in the palms and soles

Back 15

Carotene

Front 16

Responsible for the pinkish hue of skin

Back 16

Hemoglobin

Front 17

Meissner's corpuscles are __________ endings in dermal papillae, most common in _______, _______, and _______

Back 17

-encapsulated

-palmar and plantar skin, especially in fingertips.

Front 18

Meissner's corpuscles are sensitive to?

located in?

Back 18

-light touch

-dermal papillae

Front 19

Pacinian corpuscles, located deeper in dermis, are simple nerve endings but are each _________ by _________, ovoid structures resembling small onions.

Back 19

-encapsulated

-multilamellar

Front 20

Pacinian corpuscles are located _____________, are simple nerve endings

Back 20

-deeper in dermis

Front 21

Pacinian corpuscles respond to

Back 21

deep pressure and vibration

Front 22

Ruffini endings are sensitive to constant or sustained deep pressure caused by the mechanical displacement of the ___________

Back 22

collagen fibers of skin.

Front 23

Ruffini receptors are the simplest of all ________ mechanoreceptors associated to the skin.

Back 23

-encapsulated

Front 24

Ruffini have a ________ adaptive potential

Back 24

slow

Front 25

Ruffini endings are sensitive to ?

Back 25

-constant or sustained deep pressure

-skin stretching and torque

Front 26

Merkel's touch corpuscles are ________ associated with Merkel’s Cells at the base of the _______.

Back 26

-nerve endings

-epidermis

Front 27

Merkel's touch corpuscles detect

Back 27

light but constant or sustained touch

Front 28

Free nerve endings (no conspicuous, specialized structures) terminate within the __________, penetrating almost to the ___________.

Back 28

-epidermis

-stratum corneum

Front 29

Free nerve endings detect

Back 29

fine touch, pain, and temp

Front 30

main neurotransmitters of nociceptors?

Back 30

Glutamate and substance P

Front 31

fast adapting?

Back 31

phasic

Front 32

slow adapting?

Back 32

tonic

Front 33

maintain high firing rate?

Back 33

tonic

Front 34

firing rate decreases if stimulus is maintained?

Back 34

phasic

Front 35

High density of receptive fields =

Back 35

shorter minimum distance

Front 36

Low density of receptive fields =

Back 36

longer minimum distance

Front 37

abundant on
palms, soles, and forehead

Pherohormones

Back 37

merocrine/eccrine glands

Front 38

Sebum?

Back 38

sweat + fatty substances and proteins

Front 39

Ceruminous glands?

What type of gland?

Back 39

-in external ear canal; secrete
cerumen

-apocrine

Front 40

confined to axillary and anogenital areas.

special type?

Back 40

-apocrine glands

-mammary glands

Front 41

sebaceous glands use ______ secretion

Back 41

holocrine

Front 42

least malignant and most common skin cancer?

Back 42

basal cell

Front 43

most dangerous skin cancer?

Back 43

melanoma

Front 44

intermediate skin cancer?

Back 44

squamous

Front 45

In basal cell carcinoma _________ cells proliferate and slowly invade dermis and hypodermis

Back 45

stratum basale

Front 46

squamous cell carcinoma involves?

Back 46

keratinocytes of stratum spinosum

Front 47

ABCD rule?

Back 47

A: Asymmetry; the two sides of the pigmented area do not match
B: Border exhibits indentations
C: Color is black, brown, tan, and sometimes red or blue
D: Diameter is larger than 6 mm (size of a pencil eraser)

Front 48

In the granulosum cells contain the protein ___________ which organizes intermediate filaments into thick bundles.

Back 48

keratohyalin

Front 49

In the granulosum cells contain ________ which release lipid rich water repellent secretion

Back 49

lamellar granules