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13 Cards in this Set
- Front
- Back
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How do tight junctions work?
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They seal neighbouring cells in an epithelial sheet to prevent the leakage of molecules between them
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How do Adherens work?
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Joins an actin bundle in one cell to a similar bundle in the next cell
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How do desmosomes work?
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it joins intermediate filaments together in one cell to those in the next
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How do Gap junctions work?
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they are a connection which allows the passage of small water soluble ions and molecules
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How do hemidesmosomes work?
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they anchor intermediate filaments to the basal lamina
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What type of molecules can diffuse straight through a plasma membrane
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lipid soluble molecules like oestrogen hormone,, gases, small uncharged polar molecules
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What type of molecules need channels to diffuse through?
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water - aqua porins
Urea |
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Name and describe the two types of active transport mechanisms
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Primary - use the energy source directly, e.g. ATP pump, Na+/K+ pump
Secondary - use the energy source indirectly, e.g. Na+/glucose co-transport |
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Define Uniport, Symport and Antiport
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Uniport - one molecule is transported through
Symport - one molecule and a co-transported ion passes together from one side to another Antiport - one molecule moves into the cell and the other one moves out at the same time |
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Briefly, how do voltage gated channels work?
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Have a conformational change in shape when the membrane potential passes a positive threshold value causing the channel to open or close
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Briefly, how do ligand gated channels work?
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they can have either an intra or extra cellular domain and they undergo a conformational change when a chemical ligand binds to a receptor on the channel
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Mechanically gated channels
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they undergo a conformational change when there is an increase in pressure causing it to be stretched or squeezed open
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Nernst Equation
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E = (60/z) log[C (outside)] / log [C (inside)]
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