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40 Cards in this Set

  • Front
  • Back
what is physiology?
study of how living organisms work.
both broad and small (from ion movement to organ integration(
homeostasis?
a relatively stable state of equilibrium.

the tendency toward such a state between the different but interdependent elements or groups of elements of an organism, population, or
group
why are cells special?
simplest thing that can be divided and STILL retain life's functions.
when did rory butler peak?
high school
explain cell differentiation?
all cells start the same, from one cell, and differentiate into specialized cells from external chemical signals.

they also migrate to other places, form adhesions.

aggregate to form tissues, which combine to form organs, which combine to from organ systems
four major cell categories?
muscle, nervous, epithelial, connective
explain muscle cells?
generate forces to provide movement.
explain nerve cells?
initiate, conduct electrical signals. can initiate new electrical signals, or stimulate a cell.
explain epithelial cells?
specialized for selective secretion and absorption for ions, organic molecules, protection.

helps against external environment
located at surfaces of body or individual organs.

lie on an extracellular protein layer called the BASEMENT MEMBRANE, and form boundaries between a compartments, function as barriers regulating molecule exchange.
whats the external environment?
the snvuronment surrounding body
4 types of tissues?
muscle, nerve, epithelial, and connective
explain extracellular fluid?
surrounds each individual cell in the body.

has in it the extracellular matrix, having a mix of protein and sometimes minerals.
-this matrix gives scaffold for cellular attachments; also it transmits info by chemical messengers to other cells helping to regulate activity/growth/differentiation

is HOMOGENOUS
what is in protein of extracellular matrix?
FIBERS! both collagen fibers and "rubberband" elastin fubers

also NONFIBROUS PROTEINS! these have complex carbs.
what are organs made of (HINT:UNITS)
functional units, where each one can do the job of the organ
what's the internal environment?
fluid surrounding cells, in the blood.
interstitual fluid?
about 75-80% of extracellular fluid.
the PLASMA is the other 20-25% of it.
how are the concentrations of dissolved substances in plasma, interstitial fluid, and extracellular fluid?
theyre all basically equal, being that the plasma/interstit. are what make up the extracellular fluid.

however, protein is higher in the plasma than in the interstitial fluid.
homeostasis is a d-----c process?
dynamic

NOT static

means that a homeostatic physiological function is NOT so constant, in reality it is fluctuating within a predictable (narrow) range.
explain blood glucose level change in the body?
raises after a meal, then returns to normal.

they can change very much, but always come back to a medium.
dynamic constancy?
over short periods, blood glucose levels may change drastically, but over a few days it gets to a predictable average level.
explain homeostatic control systems?
activation of cells/tissues/organs to regulate with each other so any change in extracellular fluid initiates reaction to correct the change
steady state vs equilibrium?
in STEADY STATE: a system in which a variable is NOT changing, but must have energy added continuously to maintain a constant condition. (semi-cold room, body heats up to keep up with temp loss)

in EQUILIBRIUM: a particular variable is not changing, but also NO input of energy is requires to maintain the constant variable.
set point?
the operating point, or steady state point
explain homeostatic control of an extreme lowering in room temperature?
- Lowering room temp
+ heat loss from body
- body temperature, leads to constriction of blood vessels (reduces amt of warm blood flowing, so less lost), curling up (less SA to lose heat), and shivering (makes chemical reactions in muscles make heat)


all of this shit helps to return body temperature toward original value
explain negative feedback?
example?
increase/decrease of variable being regulated, tends to bring responses that move the variable in the opposite direction of the direction of original change.

without this, homeostatic oscillations would be much greater.

ex) happens as ATP is accumulated and inhibits glucose breakdown (negative feedback is on here). when ATP levels are low, negative feedback is removed and more glucose is broken down so more ATP is made.
positive feedback? example?
accelerates a process.
explosive, NOT homeostatic, since it is counter to the homeostatic principle.

no means of stopping really, less common than neg. feedback.

ex) birth. pos. feedback makes uterine contractions stronger until baby's born, then it turns off.
example of setting/reseting of SET POINT to new value?
fever. raises homeostatic control systems are maintaining body temp's at a higher level to kill more infection.

after infection is gone, the original normal body temp can return.

set points not only change in response to external stimuli but ALSO happens daily, like when you sleep = less body temp.

is adaptive.
plasma iron concentration?
the concentration is lowered during infection to deprive the infectious shit of nutrients.

brought about by natural body defense mechanisms, NOT by the infection.
what happens when homeostatic control systems cant maintain constancy in every variable?
the constancy of certain variables may be altered markedly to maintain other variables in their normal ranges.
feedforward regulation? example?
ex) the temperature sensitive nerve cells that trigger neg feedback of body temp lie inside the body.
to trigger them, other temp-sensitive nerve cells in skin immediately detect changes in outside temp and relay the signal to the nerves in the body.

it anticipates changes in regulated variables (like body temp) and improves speed of response,
reduces deviation from set point.

ex)increased heart rate of athlete before 100m dash.
reflex? other forms of reflexes?
specific, involuntary, unpremeditated, unlearned, BUILT-IN response to particular stimulus.

LEARNED/ACQUIRED reflexes are result of learning, practice.

*most reflexes are subject to alteration by learning
reflex arc?
from the stimulus to the response.
is the pathway mediating a reflex
describe reflex process?
RECEPTOR detects environmental change.
a stimulus acts upon the receptor to make signal to go to INTEGRATING CENTER thru the AFFERENT PATHWAY.

this is then output to a EFFECTOR, which causes the effectors change which completes the response. this final road is the EFFERENT PATHWAY.
describe the integrating center?
its output reflects the net effect of the total afferent input, since it receives signals from many receptors.
constriction of blood vessels, contraction of skeletal muscle (shivering) is part of what pathway in thermoregulation reflex?
the effectors.
name two major effectors of the body?
muscle, gland tissues
how do glands act as effectors?
the effector may be a hormone secreted into the blood.
hormone define?
type of chemical messenger secreted into blood by cells from endocrine system. can act on many cells at same time since they circulate thru body.
2 places the integrating center can reside?
the nervous system (efferent pathway thru nerve fibers)

an endocrine gland, the efferent pathway leading to release of hormones to blood.

additionally, the same endocrine gland can also act as receptor AND integrating center in a reflex.
local homeostatic responses?
how it is different, similar to reflex?
initiated by a change in external/internal environment (a STIMULUS).

like a reflex, is a result of sequence of events from a stimulus.

UNLIKE a reflex, the entire sequence only occurs in the area of the stimulus.
-ex) tissue cells can become metabolically active and secrete substances into the interstitial fluid that dilate local blood vessels. this causes increased blood flow which keeps increasing at the rate at which nutrients/oxygen is delivered to that area.

this helps provide individual areas of the body with LOCAL self-regulation