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32 Cards in this Set

  • Front
  • Back

Absence of disease

No attributabledetectable symptoms


Physical well-being

Aerobic exercise:larger heart muscle


Higher stroke vol


Bones stronger

Mental/social wellbeing

Difficult to identify

Physical diseases

Malfunction of organ/system (not higher centres of brain)


Pulmonary tubrculosis bacteria lung


Cystic fibrosis genetic mucus disease

Mental disease

Affect higher centres of brain


Unusual behaviour/response


Alzheimers


Huntington's chorea


Sometimes difficult to separate from physical atheroma> stroke> change

Social disease

Widespread poor hygiene/food short


Kwashiorkor


Or


Transmitted during sex


Gonorrhoea/AIDS

Infectious disease

Caused by pathogens (parasitic microorganisms)/parasites


Can be transmitted contact/water/vectors (malaria)

Viruses

Chicken pox, smallpox, flu, cold, AIDS

Bacteria

TB, cholera, meningitis, botulism, tetanus

Single cell organism (protoctista)

Malaria, sleeping sickness

Fungi

Athlete's foot, ringworm, thrush

Parasjtes

Roundworm (nematode)


Flat worm (platyhelminthes)


Elephantitis- nematode- blocks lymph vessels

Non-infectious disease

Inherited: defective allele recessive:both parent, dominant:one


Chromosome mutation:downs


Degenerative: cells die, not replaced tissue malfunction alzheimers


Autoimmunity rheumatoid arthritis


Self inflicted:toxins booze/drugs


Anorexia


Deficiency: scurvy, pellagra

Epidemiology

Health stats


Reveal where/when conditions occur


Pointers to causes for further study

Endemic

Present all the time at roughly same level


Malaria tropical africa


Goitre iodine deficiency in himalayas

Epidemic

Sudden increase infectious disease across fairly large area


Chicken pox every few years

Pandemic

Increase/spread global


Flu/AIDS

Health measures

Infant mortality 1st yr deaths /1000


Life expectanct at birth


Prevalence of diseades


%deaths by diseades

Environmental reasons for diseases

Warmer water better for pathogens parasites and insect vectors


Low rainfall no crops deficiency


Social reasons

Diet- malnutrition/colon cancer


Fertility rate. Religion, education, custom, labour

Cholera

Comma shaped vibrio cholerae


Enters mouth


Secretes toxins to alimentary canal


Affects water/salt absorbtion intestin


Copious highly infectious diarrhoea


Contam water/shelfish enters mouth


50% effective vaccine


Oral rehydration therapy prevent dehydration within 5 days


Good sanitation/health practises

Malaria

Protoctistan plasmodium


Parasite of mosquitos (vector)


4 species, 4 types of malaria


Introduced by mosquito bite


Parasites multiply in liver


Emerge, attack red blood cells


Release toxins to blood


Immune reaction, severe fevers


Difficult to treat


Pre-exposure drugs for tourists


Eradicats mosquito=water drainage


2 million deaths a year


Resurgence:resistant mosquito, deforestation, population growth, refugee movement

Tuberculosis

Mycobacterium tuberculosis


Mycobacterium bovis


Primary infection few symptoms


Healthy people fight it off.


Undernourished/unhealthy catch


Destroys lung tissue


Transmitted in breath water droplets


Damp, overcrowded best


Destroyed by sunlight


Unpasteurised milk m bovis


Good nutrition living conditions vaccination


Pasteurisation milk

AIDS

HIV first stage


Virus parasite to helper T cells


Assist t killer cells/b cell antibodies


Severely compromise immune syst


Sex, needles, blood transfer, fetus


95% unaware they have it

Vaccination

Large up front cost


Difficult to administer


Cost saving-dont have to treat illness

Smallpox

Vaccine discovered 1796


Eradicated in 70s due to communication/resources + heat stable vaccine in 50s

Eradicate smallpox but not others

No vectors in environment


Effective vaccine long term


Stable virus


Slow spread slow incubation


Always shows symptoms

Role of antibiotics

Produced saprobiontic bacteri/fungi


Halt growth of competitors


Synthetic modifications also


Penicillin alexander fleming 1928


Destroyed by stomach


Developed to amoxycillin


Tetracycline broad spectrum


Penicillin

Prevents sum bacteria cell wall form


Bacteria burst by osmosis

Tetracycline

Act at ribosome inhibit protein synth

Quinolone

Stops coiling of dna cant fit in

Antibiotic resistant

Chance mutations over generations


Survive and thrive