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88 Cards in this Set

  • Front
  • Back

Arteries

- blood away from heart


- oxygenated except pulmonary artery


- no valves


- thick elastic muscle walls


- small lumen vs. veins


- Maintain blood pressure

Veins

- Blood to the heart


- Deoxygenated except the pulmonary vein


- have Valves


- Thinner muscle walls


- Larger lumen


- Dont maintain Blood pressure

Capillaries

Take blood to every cell in the body, surround cells with thin walls for faster diffusion. Have small lumen

Pericardium

The fluid filled sac that surrounds the heart and the proximal ends of the aorta, vena-cava, and the pulmonary artery.

Pericardium functions

1. Prevents the heart from over expansion


2. Prevents infections


3. Lubricates heart (prevents infection)


4. Limits the hearts motion


5. Keeps the heart in the chest cavity

Travel through the heart

I.V.C, S.V.C > right atrium > tricuspid valve > right ventricle > pulmonic valve > pulmonary artery > lungs > pulmonary vein > left atrium > mitral valve > left ventricle > aortic valve > aorta > the body

Characteristics of the Respiratory System

1. Moist - increases diffusion rates


2. Thin - gases don't have travel far


3. High SA:V


4. Rich blood supply

Breathing IN


1. Ribs expand up and out


2. intercostal muscles contract


3. Diaphragm Contracts and moves down


4. Pressure inside thoracic cavity drops


5. Volume of the thoracic cavity has increased


6. Air rushes in to equalize pressure

7 functions of blood

1. oxygen to cells


2. carbon dioxide from cells


3. heat arund the body


4. hormones around the body


5. maintains pH levels


6. maintains osmotic potential of fluids


7. fights infection

Enzymes

Organic proteins that are catalysts


Speed up reactions


Lower activation energy


Remain unchanged



Enzymes are the keys


Substrates, enzymes act on


Substrate is lock


Substrate fits active site


Forms substrate Enzyme complex


Enzyme remains unchanged



Temperature and pH affect enzymes


Temp too high denatured


Temp too low not enough energy so not enough collision


pH too low or too high denatured


denaturation damges active site so the esc cant form


product cannot be made


6 Functions of the Digestive System

1. digestion of food


2. ingest food and water


3. chemical digestion of food


4. Movement of food through alimentary canal


5. absorption of food and water in blood and lymph


6. Eliminate unabsorbed material

3 parts of the small intestine

1. Duodenum


2. Jejunum


3. Ileum

Villi

Have microvilli attached to them


Capillaries from (arteries and veins)


Lacteal from (lymphatic vessel)


Absorptive cell


Intestinal gland


Body Cell requirements

- amino acids


- simple sugars


- fatty acids


- vitamins


- mineral


- water

GASTRIC JUICE

Mucus


HCl


Protease

Pancreatic Juice

Protease


Lipase


Amylase


Nuclease


Bicarbonate ions

Intestinal Juice

amylase (disaccharides into monosaccharides)


lipase (lipids into fatty acids and glycerol)


peptidase (peptides into amino acids)

Bile

Produced in the liver


stored in the gall bladder


emulsifies lipids


increases the SA:V of fat droplets


Lipases can work more effectively

small intestine

contains


- pancreatic juice


- intestinal juice


- bile

stomach

mechanical digestion, oblique muscle layer as well as circle and longitudinal layers.

Pancreatic Juice Enzymes

Amylase breaks down starch


trypsin or protease splits protein into smaller molecules


Rybonuclease and Deoxyribonuclease digest RNA and DNA


Lipase creak down fats into fatty acids and glycerol

Intestinal Juice Enzymes

amylase to break down disaccharides into simple sugats


peptidases to break down peptides into amino acids


lipases to break down lipids into fatty acids and glycerol

Small Intestine Features

1. About 6m long


2. mucosa has folds that extend overall SA:V


3. the mucosa has projections called villi


4. have microvilli

Absorption at the Villi

Simple sugars, amino acids, water and water soluble vitamins are absorbed into the blood cappilaries.


Fatty acids and glycerol recombine in the cells of the villi to form fats and, along with fat-soluble vitamins, enter the lacteals.


Cell membrane

made up of


- lipids


- proteins


- phospholipid bilayer


cell membranes are differentially permeable

PASSIVE PROCESSES

the cells energy from respiration is not required

ACTIVE PROCESSES

require the cells energy from respiration

3 BASIC PROCESSES IN AND OUT OF MEMBRANES

1.diffusion, a passive process resulting from random movements of ions and molecules, osmosis is the diffusion of water


2. carrier mediated transport, process that requires special proteins in the cell membrane, may be passive or active


3. vesicular transport, process where materials are moved in membrane bound sacs(active).

Diffusion

through protein channels in the membrane, very small in diameter so small molecules can pass through where as big molecules are too large

CARRIER MEDIATED TRANSPORT

there are special proteins in the cell membrane that bind to an ion or molecule and help it move across membranes. These carrier proteins are specific, they usually only bind with one particular ion or molecule

Facilitated diffusion

Many things that a cell needs, including glucose and amino acids, have molecules that are too large to fit though the cell membrane by simple diffusion. Such substances can be moved through the membrane by carrier proteins in a process called facilitated diffusion. A passive process that moves substances from a high to low conc. The transported molecule binds to a carier protein, which changes shape, moving the molecule to the opposite side of the cell membrane where it is released. Glucose is the main.

ACTIVE TRANSPORT

requires cellular energy. Although energy expenditure is a disadvantage for the cell, the big up side is it can move substances across the conc. gradient. Carrier proteins are similarly involved like facilitated diffusion. Substances like amino acids.

VESICULAR TRANSPORT

active process which materials move into or out of the cell membrane enclosed as vesicles. Also known as bulk transport as large amounts of materials can be transported.

Vesicles

Bubble-like structures surrounded by a membrane.

ENDOCYTOSIS

PHAGOCYTOSIS- cell eating (wbc)


PINOCYTOSIS- cell drinking

EXOCYTOSIS

If the contents of a cell are pushed out is called exocytosis. eg. breast milk or saliva, or digestive enzymes

endoplasmic reticulum

network of parallel membranes within the cell


used to transport substances within cell


particularly proteins the cell has made


have ribosomes attached (rough)

golgi apparatus

flattened membraneous bags on top eachother. modify proteins and package them in vesicles for secretion from the cell.

Microtubules

very fine tubes that help to maintain the shape of the cell and hold organelles in place

centrioles

a pair of cylindrical structures located near the nucleus, involved in the reproduction of the cell

ribosomes

very small and spherical, may be free in the cytoplasm but mostly attached to membranes.


amino acids are joined at the ribosomes to make proteins

mitochondria

spherical or elongated structures spread throughout the cytoplasm. cellular resp.

NUCLEUS

spherical, containing the genetic material, mostly DNA, separated from the cytoplasm by a nuclear membrane.

NUCLEOULUS

composed of RNA

Lysomes

small spheres that contain enzymes able to break down proteins, lipids, nucleic acids and some carbs.

Bacteria

- transmitted: water, vectors


- operation: releases toxins


- treatment: antibiotics


- eg: cholera

VIRUS

- transmitted: body fluids


- operation: DNA and RNA only


- treatment: anti viral drugs


- eg: HIV

PRION

- transmitted: eat infected matter


- operation: changes normal proteins to abnormal ones


- treatment: none


- eg: MADCOW

FUNGUS

- transmitted: spores


- operation: eat away at cells


- treatment: fungicides


- eg: tinea

MECHANICAL BARRIERS

provide obstacle to invading pathogens and ∆ reduce the risk of disease. most common mechanical barriers is a surgical mask. eg SARS

PAIN RELEIF

many infections cause pain, drugs reducing pain are called analgesics.

TOPICAL PREPERATION

Used on the skin, include ointments, creams gels, lotions and solutions. such as


- sunscreen


- antiseptics


- antibiotic solutions


- analgesics


- insecticides


- cosmetics

Non specific Defenses

- good hygiene


- cover mouth


- wear gloves


- wipe surfaces


- don't share personal articles

ANTIMICROBIALS

A chemical used to kill infecting micro-organisms


like antibiotics

nephron

makes urine and cleanses blood


about 1.2 million

FILTRATION

@ glomerulus


filtrate (everything but plasma protein RBC and WBC)


includes


- water - salts


- uric acid - amino acids


- creatinine - fatty acids


- hormones - glucose


- toxins - urea


- ions

SECRETION

From blood to filtrate


- potassium


- hydrogen


- creatinine


- penicillin


maintains pH of blood

RE-ABSORPTION

From filtrate to blood


- water (active, facultative reabsorption)


- amino acids


- glucose


- calcium


- hydrogen carbonate


- urea


- ions like potassium and chlorine

LIVER

deamination: the removal of the amino group from an amino acid molecule


- excess protein cannot be stored in the body


- proteins can be used for energy if carbs and fats run out


- removes NH2 converts to NH3 then to urea


- converted leftovers in carbs

CELL DIVISON

includes


-mitosis: growth. maintenance and repair


-meiosis: fro sexual reproduction

MITOSIS

- cells reproduce so that organs can grow larger


- cells that are damaged, worn out or diseased must be replace


MITOSIS .0

DNA determines the types of proteins we can make


vital that when we reproduce the daughter cell gets the exact same dna

MITOSIS PHASES

INTERPHASE


PROPHASE


METAPHASE


ANAPHASE


TELOPHASE


CYTOKENESIS

INTERPHASE

dna molecules duplicate

PROPHASE

nucleoli dissappear


nuclear membrane breaks down


centrioles migrate to opposite poles


chromosomes appear as pairs of chromatids


spindle forms

METAPHASE

chromosomes line up on the spindle at the equator of the cell

ANAPHASE

centromeres divide


chromosomes move to opposing poles

TELOPHASE

spindle disappears


nuclear membranes and nucleoli form


centrioles divide


chromosomes uncoil and disappear


CYTOKENESIS

cytoplasm of the cell divides into two each with a nucleus

MEIOSIS

HALF THE NUMBER OF chromosomes for sex cell production

Prophase 1

chromosomes become visible as long threads


already duplicated has pair of chromatids


dna becomes tightly coiled


spindle forms spreading between poles


crossing over may occur

metaphase 1

paired chromosomes are arranged on the spindle fibres across the center of the cell

anaphase 1

thw pair of homologous chromosomes move apart, with one member of each pair moving to one pole of the cells


the number of chromosomes at each pole is half

telophase

the cytoplasm may divide into two parts

prophase 2

a new spindle forms at each end of the original spindle and usually at right angles

metaphase 2

chromosomes are arranged on the new spindle


chromsomes migrate to opposite poles of the cell

anaphase 2

nuclear membranes begin to form and the cytoplasm starts to divide

telophase 2

by the end of the second divison 4 new cells have been formed, each with half the number of chromosomes as the original cell

mitosis vs meiosis

mitosis


one duplication


produces two diploid cells


chromatids seperate so each new cell gets a complete set of daughter chromosomes


new cell for growth and reapair


meiosis


one duplication and two divisions


produces 4 haploid cells


homologous pairs seperate so each new cell gets haploid set of chromosomes


genetic make up of chromosomes can be altered due to crossing over


produces haploid gametes for sexual reproduction

SPERMATOGENESIS

spermatogonia


mitosis


daughter cell spermatogonia


mitosis


primary spermatocyte


meiosis 1


secondary spermatocyte


meiosis 2


spermatids


spermatozoa(mature

OOGENESIS

(prebirth) oogonia


mitosis


primary oocyte


meiosis 1 (stops at p1)


primary oocyte


completes meiosis 1


secondary oocyte + polar body


meiosis 2


ootid/ovum

ovarian cycle

follicle stim hormone acts on follicle


follicle sectretes oestrogen


leutenising hormone


corpus luteum secretes progesterone


build up lining

gene

genes are made up of DNA, they are a small part of the whole DNA molecule. gene carrys the info that determines the characteristics


20000 genes on each chrom.


3 nucleotides make an amino acids

PROTEIN SYNTHESIS

messenger RNA: copies the gene info from dna moves out into the cytoplasm, via nuclear pores, to the ribosome (codon)


transfer Rna: collects amino acids from within the cytoplasm and arranges them into proteins according to the messenger rna (anticodon)


Ribosomal RNA: bonds amino acids together to form a protein

mutations

show variation that doesnt resmeble either rental

gene mutations

changes a single gene so that the traits are changed

chromosomal mutations

all or part of the chromsome is affected

mutagens

mustard gas


sulfur dioxide


antibiotics