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42 Cards in this Set

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Definition of nerve
parallel bundles of peripheral axons (myelinated and unmyelinated) enclosed by successive wrappings of connective tissue.
What surrounds each axon (myelin sheath)
Endoneurium
What wraps bundles of axons into fascicles
perineurium
What encloses bundles of fascicles and blood vessels
epineurium
What types of nerves exist.
- mixed nerves, sensory nerves, motor nerves, somatic and autonomic.
- these peripheral nerves are either cranial or spinal.
What are ganglion and what is the difference between ganglion of the afferent and efferent nerve fibers.
Ganglia: collection of neuron cell bodies associated with nerves of PNS
- afferent ganglia are associated with sensory neurons
- efferent ganglia are associated with autonomic motor neurons.
How do motor endings activate effectors?
By releasing NT.
General overview on Cranial nerves.
- 12 nerve pairs: (first two pairs attached to forebrain and the rest originate in brainstem)
- cranial nerves deal with neck/head (with exception of vagus nerve)
- 3 pairs sensory
- 5 pairs motor
- rest mixed
Gray matter of spinal cord is composed of?
- neuron cell bodies
- unmyelinated processes
- neuroglia
It composes
- anterior ventral horns of lateral horns
- posterior or dorsal horns.
White matter in the spinal cord is composed of?
-myelinated/unmyelinated fibers
- can run in ascending and descending directions
- can be commissural
Posterior Horn takes care of ______ info
Sensory
Lateral horn takes care of __________ info
Autonomic motor -- visceral motor neuron
Anterior Horn takes care of ______ info
somatic motor
How many non-cranial spinal nerves exist.
- 31 pairs
- supply all parts of the body except the head and some areas of the neck
- all are mixed nerves: 8 pairs of cervical nerves, 12 pairs of thoracic, 5 pairs of lumbar, 5 pairs of sacral, 1 pair of coccygeal.
All spinal nerves have both dorsal and ventral roots. How do these divide and what is their function.
Dorsal ramus and ventral ramus. These are found before the info splits into the dorsal and ventral roots.

Dorsal rami: supply the posterior body trunk
Ventral rami: supply the rest of the body trunk and limbs.
More specific information on the Dorsal Rami
- supplies the posterior body trunk
- each dorsal ramus innervates or receives input from a narrow strip of muscle and skin in line with its emergence point from spinal cord.
- think of painted man
Ventral Rami of thoracic nerve
wrap forward along with the rib and sit in the intercostal nerve.
General info on the ventral rami of nonthoracic spinal nerves
- branches profusely and form networks of nerves called plexusus
- major plexuses occur in the cervical, brachial, lumbar, and sacral regions
- within each plexus the fibers of the ventral rami crisscross each other: each branch of plexus contains fibers from several spinal nerves, fibers from each spinal nerve carried to body periphery via several routes.
Info on Plexus
It is a complex network of the ventral rami of non-thorasic spinal nerves.
- Because so many sort of safe guard essential sensory routes so if one is injured, there are backups.
What is the Autonomic Nervous system?
system of neurons that innervates smooth and cardiac muscles and gland; involuntary division of PNS.
Used in:
- glands
- cardiac muscle
- smooth muscle.
Summary of Nervous system organization
- efferent division of PNS
- SNS: innervates skeletal muscles; voluntary PNS division
- ANS: system of neurons that innervates smooth and cardiac muscle and glands; involuntary division of PNS
Difference s in what SNS and ANS stimulate
SNS: stimulates skeletal muscles
ANS: stimulates cardiac and smooth muscles and some glands.
Differences in efferent pathways of SNS and ANS
SNS: Cell bodies of motor neurons are in the CSN, their axons extend in spinal nerves to skeletal muscles they serve
ANS: system has set of distinct effectors. Two neuron motor pathways.

The preganglionic neuron is the cell body in the CNS and the postganglionic neuron is in ganglion outside of CNS which will extend to the effector organ.
What is similar with both sympathetic and parasympathetic divisions of the ANS
Both use 2 neurons
- Both 1st release AcH
- 1 neuron starts in CNS
- Second neuron ends in whatever is being innervated.
What is the difference between the sympathetic and parasympathetic branch of ANS
- sympathetic: second neuron releases Norepinephrine or epiniphrine, the primary neuron is generally shorter than the second (with the exception of adrenal medulla communication because it just release NT to effect an organ)

Parasympathetic:
- 1st neuron is longer
- AcH is released from both neurons.
Only _________ of ANS are myelinated
preganglionic cells.
What is the purpose of having both a sympathetic an parasympathetic division of ANS
The both serve same visceral organs but they cause essentially opposite effects -- dual innervation
Parasympathetic Division
- "resting and digesting"
- keeps energy use low while maintaining vital functions
- preganglionic fibers: craniosacral orgin; long preganglionic fibers,
- short postganglionif fibers
Sympathetic Division
- "fight or flight" takes over during stressful or emotional situations
- preganglionic fibers: thoracolumbar origin; short preganglionic fibers, long post ganglionic fibers.
- ganglia are close to the spinal cord.
What areas of the body do not use the dual innervation system.
Blood Vessels: innervated by sympathetic nerve fibers: sympathetic = constriction = increased blood pressure.
- sweat glands - innervated only by sympathetic nerve fibers
- Salivary glans - innervated by both division but activities not antagonistic
: PS - enzyme rich saliva
: SYM - mucous rich saliva : stress: drymouth.
Stress equals which branch of ANS
Stress = Sympathetic = Saliva = Scary movie = Fight or flight.
How is the adrenal medulla effected by the ANS
It is part of the sympathetic ANS and it works as the second neuron being excited by ACH and releasing Epinephrine or NE into the Blood to effect the smooth muscle.
Overview of parasympathetic division
- long preganglionic axons
- short postganglionic axons
- ganglia very close to or within target organ
- PS endings and effects
- Cranial outflow: effects can be brought on by cranial nerves
What is sacral outflow
parasympathetic signals which originate from the neurons located in the lateral gray matter of sacral spinal cord segment.
Overview of sympathetic division
- short preganglionic axons
- long postganglionic axons
- gangila far removed from target organ
- preganglionic fibers arise from cell bodies located in lateral horns of spinal cord segments
Examples of sympathetic ganglia
- sympathetic chain gangila
- collateral gangila
- Adrenal medulla
What does each type of ganglionic neuron target.
- sympathetic chain ganglion: visceral effectors in thoracic cavitity, head, body wall, and limbs: CLOSER TO SPINAL CORD
- Collateral ganglia (unpaired) visceral effectors in abdominopelvic cavity: FURTHER FROM SPINAL CORD
- Adrenal medullae: organs and systems throughout the body.
What do you call a fiber that releases Ach vs. Epinephrine
ACh = cholinergic fiber - always released by preganglionic fibers and effects are always excitatory. Can be release by postganglionic too.
E/NE = adrenergic fiber
Overview of ANS: neurotransmitters
- each autonomic NT can stimulate activity in some tissue and inhibit activity in others
-particular responses depend on specialization of tissue cells, not the NT themselves
- Responsive tissue cells pocssess one or more of several different receptors for these chemicals.
What do cholinergic receptors of ACH do and what are two examples.
The bind ACh.
Two examples:
- nicotinic receptors
- muscarinic receptors.
What do Nicotinic receptors do;
- bind ACh
- all postganlionic neuron receptive regions; hormone producing cells of adrenal medulla
- also in motor end plate of skeletal muscle
- activated by nicoted
- usually excitatory
What do Muscarinin receptors do?
effect cells of postganglionic parasympatheict fibers.
- different types M1, M2 ...
- activated by muscarine
- Atropine is antagonist.