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86 Cards in this Set

  • Front
  • Back

Digestion

Breakdown of ingested food


Absorption of nutrients into the blood

Metabolism

Prod'n of cellular ATP


Constructive and degradative cellular activities

Layers of Alimentary Canal Organs

Mucosa


Submucosa


Muscularis Externa


Serosa

Mucosa

Innermost layer


Moist membrane


- Surface epithelium

Submucosa

Just beneath the mucosa


Soft conn. Tissue w. Blood vessels/nerve endings and lymphatics

Muscularis Externa

Smooth Muscle


- Inner circular layer


- Outer longitudinal layer

Serosa

Outermost layer - visceral peritoneum


Layer of serous fluid - prod. Cells

Carbohydrates are broken down into....

Simple sugars (mostly glucose)

Proteins are broken down into....

Amino acids

Fats are broken down to...

Fatty acids and alcohols

Absorption

End prod. Of digestion are absorbed in blood/lymph


Food must enter mucosal cells and then into blood or lymph capillaries

Defecation

Elimination of indigestible substances as faeces

Lips

Protect anterior opening

Cheeks

Forms lateral walls

Hard palate

Anterior roof

Soft palate

Forms posterior roof

Uvula

Fleshy projection of the soft palate

Vestibule

Space between lips externally and teeth and gums

Oral cavity

Area cont. By the teeth

Tongue

Attached at hyoid and styloid processes of the skull, and by the lingual frenulum.

Tonsils

Palatine


Lingual

Salivary glands

Parotid


Submandibular


Sublingual

Bolus

Ball of food formed in mouth after mastication

Classification of Teeth

TOP JAW ONLY


Incisors (4)


Canines (2)


Premolars (4)


Molars (6)

Regions of a tooth

Crown (exposed pt.)


Neck


Root

Crown

Outer enamel


Dentin


Pulp cavity

Neck

Region in contact w. Gum


Connects crown > root

Root

Periodontal membrane attached to the bone


Root canal carrying blood vessels and nerves

Function of Pharynx

Passageway for air/food


Food propelled to oesophagus by longitudinal inner and circular outee layer


Via peristalsis

Gastroesophageal reflex disease

If lower sphincter fails to open


- distension of oesophagus feels like chest pain/❤ attack


" " close


- stomach acid enters oesophagus ➡❤🌋

Peritoneum

Visceral layer covers organs


Parietal layer lines walls of body cavity

Peritoneal cavity

Potential space containing a bit of serous fluid

Rugae (stomach anatomy)

Internal folds of mucosa

External regions (stomach anat)

Lesser & greater curvature

Lining of stomach??

Simple columnar epithelium


- mucous neck cells


- gastric glands


- chief cells


- parietal cells


- endocrine cells

Mucous neck cells

Prod. Sticky alkaline mucous

Gastric glands

Secrete gastric juice

Chief cells

Produce protein-digesting enzymes e.g. pepsin

Parietal cells

Produce HCl acid

Endocrine cells

Prod. Gastrin

Stomach Func.

Storage tank for food


Site of food breakdown


Chem. Breakdown of protein begins


Delivers chyme (processed food) to small intestine.

Chem. Breakdown in stomach

Pepsinogen(inactive) ➡ pepsin (active)


HCl


Rennin

Protein digestion in stomach

HCl denatures protein molecules


HCl transforms pepsinogen into pepsin that breaks peptides bonds b'ween certain amino acids

Fat digestion in stomach

Rennin!


Gastric lipase splits triglycerides into milk fat

Pyloric sphincter...

Meters out chyme into small intestine

Small Intestine

Maj. Digestive organ


site of nutrient absoption ➡ blood


Duodenum ➡ jejunum ➡ ileum

Mesentery

Suspends S. Intestine

Duodenum

Att. To stomach

Jejunum

Att. Interiorly to duodenum

Ileum

Extends from jejunum to L intestine

Structure of villi

Absorptive cell


Blood capillaries


Lacteals

Intestinal amylases

Maltase


Sucrase


Lactase

Intestinal enzymes

Intestinal amylases


" " lipase


" " protease


- aminopeptidase

Bile + pancreatic juice

Support digestion in S. Intestine

Pancreas

Exocrine func. ➡ prod. Of digestive enzymes


Endocrine func. ➡ secretion of insulin

Secretin

Stim. the release of watery bicarbonate sol'n that neutralises acidic chyme

Cholecystokinin

AND VAGUS NERVE AStim. Release of digestive enzymes.

Composition of pancreatic juice

H2O, enzymes, Nabicarbonate


Digestive enzymes

Digestive enzymes of Pancreas

Pancreatic amylase


Pancreatic lipase


Pancreatic proteases

Pancreatic proteases

Trypsinogen


Chymotrypsinogen


Procarboxypeptidase


Trypsin inhibitor

Trypsinogen

Activated to Trypsin

Chymotrypsinogen

Activated by trypsin

Procarboxypeptidase

Activated by trypsin

Trypsin inhibitor

Combines with any trypsin if prod. Inside pancreas thus prev. Any digestion of pancreas by its own trypsin

Liver

4 lobes


Connected to gall bladder via common hepatic duct

Bile

PROD IN LIVER


Composed of


Bile salts


Bile pigment (bilirubin)


Cholesterol


Phospholipids


Electrolytes

Gall Bladder

Sac found in hollow fossa of liver


Stores bile via cystic duct


Introd. Into duodenum in presence of fatty food

Bile salts

Emulsifies lipids

Digestion of fat

Large intestine

Ascending/transverse/descending colon


Rectum

Functions of L Intestine

Absorption of H2O


Eliminates indigestible food as faeces


Does not digest anything


Goblet cells prod. Mucus for lubricant

Categories of Nutrients

Carbs


Lipids


Proteins


Vits.


Minerals


H20

Catabolism

Substances broken down (energy released)

Anabolism

Smaller molecules ➡ larger

Carb metabolism

Glycolysis

Glucose ➡ 2 pyruvic acid molec. + ATP

Krebs cycle

2 (pyruvic acid) ➡ CO2 + H2O + 30 ATP (when NADH2 & FADH2 are joined to e- trans. chain ➡ ATP & H2O)

Fat metabolism

Fats ➡ acetyl CoA ➡ H2O + CO2 + ATP

Protein metabolism

Protein ➡ amino acids + ammonia


Ammonia ➡ urea

Role of livee in metabolism

Digestion


Detoxifies drugs/alcohol


Degrades hormones


Prod. Cholesterol and blood proteins

Glycogenesis

Glucose ➡ glycogen


Glycogen stored in liver

Glycogenolysis

Glycogen ➡ glucose and is released from liver

Gluconeogenesis

Fats/proteins ➡ glucose

Functions of cholesterol

Serves as structural basis of steroid hormones and vit. D


Building block of plasma membranes

Body temp normal

37

Function of hypothalamus

Vaso dila/constriction