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114 Cards in this Set

  • Front
  • Back
what are the three main planes through the human body?
1. coronal (front and back)
2. transverse (top and bottom)
3. mid-sagital (right and left)
what are the two body regions?
axial -head, neck, trunk
appendicular -upper and lower limbs
the axial region of the body is divided into what two areas?
posterior aspect
ventral cavity
the ventral cavity half of the axial region contains what cavities?
thoracic and abdominopelvic, separated by the diaphragm
both the abdominopelvic and thoracic cavities are lined with what?
serous membrane
what are the two layer of serous membrane?
parietal (lines body wall) and visceral (lines organs)
what is the purpose of serous fluid in serous membrane cavity?
lubricant
the thoracic cavity is derived from where during development?
coelom
what is the median space in the thoracic cavity called? what does it contain?
the mediastinum -contains the heart, thymus, esophagus, trachea and major blood vessels
the ventral cavity is composed of what?
thoracic and abdominopelvic
what are the two components of the abdominopelvic cavity?
the abdominal cavity and the pelvic cavity
what organs are found in the abdominal cavity?
most organs of the digestive system, spleen, kidneys and ureters
what organs are found in the pelvic cavity?
distal portion of large intestine, urinary bladder, urethra, reproductive organs
which serous membrane(s) are found in the thoracic cavity?
pluera and pericardium
which serous membrane(s) are found in the abdominopelvic cavity?
peritoneum
what are the lines that make up the nine regions on the abdominopelvic cavity?
midclavicular line (vertical lines)

subcostal line (top)

intertububercular line (bottom)
what are the three types of histological microscopy? which produces 3d image? 2d image?
LM -2d
TEM -2d
SEM -3d
what is the typical size of a human cell?
1-100 micrometers
what are the 8 functions of cells?
1. covering
2. lining
3. storage
4. movement
5. connection
6. defense
7. communication
8. reproduction
what are the components of cellular cytoplasm?
cytosol
cytoskeleton
inclusions
organelles
what are the three lipid components of the plasma membrane?
1. phospholipids (75%)
2. cholesterol (20%) strengthens and stabilizes bilayer
3. glycolipids (10%) contribute to glycocalyx ; lipid with carb group attached
which type of membrane protein may serve as an enzyme?
both! integral and peripheral
what forms the glycocalyx?
the carbohydrate groups attached to both membrane glycolipids and integral glycoproteins
what are the functions of membrane proteins?
receptor
enzyme
cell-id
cell-adhesion
channel proteins
transport proteins
what are the types of passive transport?
filtration, osmosis, simple diffusion, facilitated diffusion
what are the three functions of the glycocalyx?
1. communication
2. recognition
3. adhesion
(protection? in slide)
what are the components of the cytoskeleton?
microfilaments (actin)
intermediate filaments
microtubules (tubulin)
what does the RER do?
synthesize protein, lysosomal enzymes
where are ribosomes found?
RER
free in cytosol
nucleolus
mitochondria
nuclear envelope
where is rRNA synthesized?
in the nucleolus of the nucleus
what are the two distinct things that occur during mitosis?
mitosis -division of the nucleus

cytokenesis -division of the cytoplasm
the end of prophase is characterized by what?
break down of nuclear envelope
what is the single cell produced by fertilization?
zygote
what is the spherical, multicellular structure that the zygote becomes?
blastocyst
what are the three pre-natal periods?
1. pre-embryonic
2. embryonic
3. fetal
what event marks the end of the pre-embryonic pre-natal period?
implantation of the blastocyst in the uterine lining
what is the embryonic period of development?
the 3rd thru 8th week, rudimentary versions of major organ systems start appearing in the cell mass which is now called an embryo
the developmental processes that occur in the pre-embryonic and embryonic periods are known collectively as what?
embryogenesis
what are the three main differences between mitosis and meiosis?
1. mitosis produces 2 identical daughter cells, while meiosis produces 4 genetically different daughter cells

2. mitosis produces diploid daughter cells; meiosis produces haploid daughter cells

3. crossing over occurs between homologous chromosomes in meiosis, and not in mitosis
what is the corona radiata?
cuboidal cells that surround secondary oocyte as it is ovulated
what is the zona pellucida?
a ring of proteins and glycoproteins that surround the secondary oocyte during ovulation
when during meiosis does crossing over occur?
during prophase of meiosis I
what are the three phases of fertilization?
1. corona radiata penetration
2. zona pellucida penetration
3. fusion of the sperm and oocyte plasma membranes
what happens during the slow-block of polyspermy?
calcium ions enter egg with sperm causing secretory vesicles within egg to release cortical granules at egg surface creating fertilization membrane
what is the fast block to polyspermy?
sodium channels
what digestive enzymes are exocytosed in order to penetrate the zona pellucida?
acrosin & hyaluronidase
when does the secondary oocyte complete meiosis II?
after the sperm enters the oocyte
following the completion of meiosis by the oocyte, the nuclei of the sperm and egg are called what?
pronuclei
when the pronuclei fuse within the oocyte, a diploid cell called a what is formed?
zygote
during the pre-embryonic stage when cleavage is taking place, what is the process that causes the contact between cells to increase to the maximum?
compaction
when will the diameter of the cell mass undergoing mitotic cleavage finally change in diameter?
after in implants in the uterus
when does the pre-embryo become a blastocyst?
in the uterine lumen prior to implantation
what causes the formation of the blastocyst cavity within the morula?
as the morula enters lumen of the uterus, fluid begins to leak through the degenerating zona pellucida resulting in a fluid filled cavity
what are the two distinct components of the blastocyst?
1. trophoblast
2. embryoblast
the trophoblast is the portion of the blastocyst that is a precursor for what?
the placenta (chorion, specifically)
what are the two layers of the endometrium? in which layer does the blastocyst implant?
stratum basale and stratum functionalis (blastocyst implants in functionalis)
the trophoblast of the implanting blastocyst differentiates into what 2 layers?
syncytiotrophoblast (outer layer)
cytotrophoblast (inner layer)
what is the "conceptus"?
all products of conception
toward the end of the implantation process, (around day 8) what changes are taking place in the cells of the embryoblast portion of the blastocyst?
they are beginning to differentiate into 2 layers: the epiblast and the hypoblast ...together called the bilaminar germinal disc
what are the epiblast and the hypoblast collectively called?
the bilaminar germinal disc
what are the extraembryonic membranes that form towards the end of the implantation process?
the yolk sac, amnion, and chorion
the amnion is continuous with which portion of the blastocyst?
epiblast
the yolk sac is continuous with which portion of the blastocyst?
hypoblast
the chorion is continuous with which portion of the blastocyst?
cytotrophoblast and synctytiotrophoblast
where does the fetal portion of the placenta develop from?
chorion
where does the maternal portion of the placenta come from?
the functional layer of the endometrium
where does the mother get estrogen and progesterone form during the first trimester while the placenta is still developing?
the corpus luteum in the ovary
what are the main functions of the placenta?
1.exchange nutrients, waste products and gases

2.transmission of antibodies to fetus

3.production of hormones (estrogen and progesterone) to maintain the uterine lining
what processes occur during the embryonic period?
gastrulation and organogenesis
during gastrulation, cells of the ______, migrate and form the three primary germ layers, from which every tissue in the body will develop. what are the three germ layers?
cell of the epiblast form the ectoderm, mesoderm and endoderm
when does a blastocyst become an embryo?
when the three primary germ layers have been formed from epiblast
what is the first step of gastrulation?
formation of the primitive streak- a thin depression on the surface of the epiblast
what are blastomeres?
the first 2 identical cells following the first cleavage
when do the extaembryonic membranes start forming?
shortly after implantation
what is gastrulation?
the establishment of the three primary germ layers
what is invagination?
the process during gastrulation that involves the detachment of cells from the epiblast and their migration thru the primitive steak between the hypoblast and epiblast layers
in what order are the three germ layers formed?
mesoderm first, then endoderm, then ectoderm
during gastrulation, cells of the hypoblast become what germ layer?
endoderm
during gatrulation, cells of the epiblast become which germ layer?
ectoderm
what are the two types of folding that occur in the embryonic stage following gastrulation? what does each type of folding give rise to?
1.cepahlocaudal folding- future head and buttocks

2.transverse (lateral) folding- future trunk (torso)
what are somites?
the block-like masses of mesoderm that appear after neurulation and give rise to axial skeleton, conn. tissue, cartilage, and dermis
when is developing baby most vulnerable to teratogens?
emrbyonic period -organogenesis!
what is a karyotype?
the number and appearance of chromosomes in cell
what is the name of the structure that implants in the uterus?
blastocyst
what is an example of a mixed gland?
salivary
what are the three types of gland secretions?
1. serous (mammary gland, sweat gland)
2. mucous (goblet cells)
3. mixed (salivary gland)
which type of cartilage resists compression?
fibrocartilage
which type of cartilage is found in the ear?
elastic
which type of cartilage does not have a perichondrium?
fibrocartilage
what are the layers of the epidermis?
1. stratum corneum
2. stratum lucidium
3. stratum granulosum
4. stratum spinosum
5. stratum basale
what are the layers of the dermis?
papillary and reticular
where in the epidermis are merkel cells found?
stratum basale
where in the epidermis are dendritic cells found?
stratum spinosum
which layer of the epidermis contains keratinocytes filled with the protein eleidin?
stratum lucidium (only in thick skin!)
in which layer of the epidermis does keratinization occur?
stratum granulosum
where are tactile cells and melanocytes found ?
in the stratum basale of the epidermis
where are dendritic cells found?
in the the stratum spinosum of the epidermis
where are keratinocyte stem cells found?
in the stratum basale
when do keratinocytes fill with eliedin?
when they reach the stratum lucidium in thick skin
when do keratinocytes undergo keratinization?
the stratum granulosum! cells flatten
______________ are responsible for "finger-prints"
dermal papillae / epidermal ridges

epidermis and dermis "zip" together
what are the two types of melanin?
eumelanin (brownish black) phenomelanin (reddish yellow)
what types of connective tissue does the dermis have?
areolar and dense irregular
which is the actively growing area of a nail?
the nail matrix
what is the hyponychium?
the epidermis under the free edge of nail
what is the epinychium?
cuticle of nail (dead cells)
what is the lunula?
white half-moon proximal nail plate due to stratum basale underneath
what is a pilus?
hair
what are the three types of hair?
lanugo, terminal and villus
when does hair get nutrition to grow?
dermal papillae
the hair follicle consists of which two parts?
connective tissue root sheet and epithelial root sheath
what is a ceruminous gland?
in auditory canal-produces earwax!
what type of gland secretes earwax in the auditory canal?
ceruminous glands
how is sweat "squeezed" from gland?
myoepithelial cells