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64 Cards in this Set
- Front
- Back
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Bumex
|
Bumetanide
(loop high ceiling diuretic) |
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Lasix
|
furosemide
(loop high ceiling diuretic) |
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Demadex
|
torsemide
(loop high ceiling diuretic) |
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Edecrin
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ethacrynic acid
(loop high ceiling diuretic) |
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What's the mechanism of action for loop diuretics?
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Site = thick ascending limb of Henle loop (25% Na reabsorption)
Action = inhibition of Na/K/2Cl symporter |
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What are the effects of loop diuretics on urine flow and ion excretion?
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-Increase of urine flow
-Increase excretion of Na, K, Cl, Ca, Mg |
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What are the main adverse effects of loop diuretics?
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-Volume depletion
-Hypo (Na,K,Cl,Ca,Mg) -Ototoxicity |
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Hygroton
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chlorthalidone
(thiazide diuretics) |
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Lozol
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indapamide
(thiazide diuretics) |
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Microzide
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hydrochlorothiazide
(thiazide diuretics) |
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Zaroxolyn
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metolazone
(thiazide diuretics) |
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What is the site and mechanism of action for thiazide diuretics?
|
Site = distal convoluted tubule (5% Na reabsorption)
Action = inhibition of Na/Cl symporter |
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What are the effects on urine flow and ion excretion in thiazide diuretics?
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-Moderate increase of urine flow
-Increased excretion of Na, Cl, K -Decreased excretion of Ca |
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What are the main adverse effects of thiazide diuretics?
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-Hypotension
-Hypokalemia (increased risk of arrhythmias) -Red glucose tolerance -Hyperuricemia |
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Midamor
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amiloride
(K-sparing diuretic) |
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Dyrenium
|
triamterene
(K-sparing diuretic) |
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Inspra
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eplerenone
(K-sparing diuretic) |
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Aldactone
|
spironolactone
(K-sparing diuretic) |
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What are the site and mechanism of action for K-sparing diuretics?
|
Site = late distal tubule and collecting duct
Action = inhibition of epithelial Na channels / blockade of aldosterone receptors |
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What are the on urine flow and ion excretion with K-sparing diuretics?
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-Slight increase in urine flow
-Slight increase of Na, Cl excretion -Decrease excretion of K |
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What are the main adverse effects of K-sparing diuretics?
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-Hyperkalemia
-Increased risk for arrhythmias |
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azilsartan
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Edarbi
(ARB) |
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candesartan
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Atacand
(ARB) |
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eprosartan
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Teveten
(ARB) |
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irbesartan
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Avapro
(ARB) |
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losartan
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Cozaar
(ARB) |
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olmesartan
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Benicar
(ARB) |
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telmisartan
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Micardis
(ARB) |
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valsartan
|
Diovan
(ARB) |
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nifedipine ER
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Procardia XL, Adalat CC
(CCB) |
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nicardipine SR
|
Cardene SR
(CCB) |
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amlodipine
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Norvasc
(CCB) |
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isradapine
|
Dynacirc
(CCB) |
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felodipine
|
Plendil
(CCB) |
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nisoldipine
|
Sular
(CCB) |
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diltiazem ER
|
Cardizem CD, Tiazac
(CCB) |
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diltiazem SR
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Cardizem SR, Dilacor XR
(CCB) |
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verapamil SR
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Calan SR, Isoptin SR, Verelan
(CCB) |
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verapamil ER
|
Covera HS, Verelan PM
(CCB) |
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atenolol
|
tenormin
(B1) |
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betaxolol
|
Kerlone
(B1) |
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bisoprolol
|
Zebeta
(B1) |
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metroprolol tartrate
|
Lopressor
(B1) |
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metoprolol succinate
|
Toprol XL
(B1) |
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nevibolol
|
Bystolic
(B1) |
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nadolol
|
Corgard
(Nonselective) |
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propranolol
|
Inderal
(Nonselective) |
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propranolol LA
|
Inderal LA
(Nonselective) |
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timolol
|
Blocadren
(Nonselective) |
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acebutolol
|
Sectral
(Intrinsic) |
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carteolol
|
Cartrol
(Intrinsic) |
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penbutolol
|
Levatol
(Intrinsic) |
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pindolol
|
Visken
(Intrinsic) |
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carvedilol
|
Coreg
(Mixed a & b) |
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carvedilol phosphate
|
Coreg ER
(Mixed a & b) |
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labetolol
|
Trandate, Noromodyne
(Mixed a & b) |
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doxazosin
|
Cardura
(a1 blocker) |
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prazosin
|
Minipress
(a1 blocker) |
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terazosin
|
Hytrin
(a1 blocker) |
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clonidine
|
Catapress
(a2 blocker) |
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clonidine patch
|
Catapress-TTS
(a2 blocker) |
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guanfacine
|
Tenex
(a2 blocker) |
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guanebenz
|
Wytensin
(a2 blocker) |
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methyldopa
|
Aldomet
(a2 blocker) |
