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15 Cards in this Set
- Front
- Back
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What are the high-risk HPV strains? |
1. 16, 18, 31, 33 2. Many more |
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What area of the female anatomy serves as a nidus for HPV progression? |
1. Transformation zone 2. Endocervix--- columnar epithelium 3. Ectocervix--- squamous epithelium |
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What are the risk factors for HPV infection? |
1. Sexual activity 2. Multiple partners 3. Younger age at sexual debut 4. Lack of condom use |
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What are the risk factors for persistent HPV infection/neoplastic progression? |
1. Smoking 2. High-risk HPV infection 3. Increasing age 4. Lack of condom use
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What are the three parts of the approach to cervical cancer prevention? |
1. Screen through cytology 2. Evaluate positive screen with colposcopy and cervical bx 3. Tx of women with bx-confirmed high-grade cervical cancer precursors |
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What is the use of liquid-based cytology? |
1. Reflex HPV testing 2. Can also test for gonorrhea and chlamydia |
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What are the recommendations for HPV screening? |
1. Start at 21--- Continue every 2 years until 30---- 2. At 30, if no + bx, change to every 2-3 years 3. End at 65-70 if there is hx of 3 normal paps in past 10 years
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What are the guidelines for screening for HPV in a hysterectomy patient? |
1. Not necessary |
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What are the classifications of squamous dysplasia? |
1. ASC-US 2. ASC-H 3. LSIL 4. HSIL |
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What are the glandular cell abnormalities? |
1. AGC 2. NOS 3. Atypical glandular cells, favor neoplastic 4. AIS 5. Adenocarcinoma |
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What is the significance of ASC-US? |
1. Half of all CIN 2/3 are dx in women with ASC-US |
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What is the significance of ASC-H? |
1. Higher risk for CIN 2/3 than in ASC-US |
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What is the significance of LSIL? |
1. Good indicator of HPV infection
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What is the significance of HSIL? |
1. 2% of women with HSIL have invasive cancer |
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What is the significance of AGC? |
1. More common in women 40 years and older 2. 3-17% have invasive cancer |
