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18 Cards in this Set
- Front
- Back
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what cytokine induces the acute phase response
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IL-6
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what two proteins are mainly involved in the acute phase response
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C-reactive protein
Mannose binding lectin |
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the acute phase response acts on the
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liver
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what three components are a part of the induced innate response
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summoning of neutrophils (IL-8)
fever (TNF, IL-1, IL-6) acute phase response (IL-6) |
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T and B cells are a part of what stage in immunity
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adaptive immunity
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how do T cells enter the lymph nodes
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high endothelial venules (HEV)
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Th1 cells respond to
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viral infection
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Th1 cells stimulate the release of
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IFN-gamma
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Th2 are important for the elimination of
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extracellular pathogens
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helper T cells express
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CD4
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cytotoxic T cells express
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CD8
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CD8 T cells recognize what class of MHC
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MHC class I
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B cells mature to
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plasma cells which secrete immunoglobulin
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Ig has 3 functions in the response to infection:
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neutralize
opsonize activate complement |
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Virus infected cells secrete
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Type I interferons: IFN-alpha and INF-beta
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virus infected cells express what ligand that binds the activating receptors on NK cells
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MIC proteins
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MIC ligands bind
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NKG2D - activating receptors on NK cells
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healthy cells inhibit NK cells by
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binding to KIR inactivating receptors
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