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85 Cards in this Set

  • Front
  • Back

Hospital Acquired Infections

Nosocomial Infection: infectious disease that is acquired or develops during a hospital stay


◦ Typically presents 48-72 hours post-admission
◦ Most agents are opportunistic
◦ Cost time, money and add to patient suffering


◦ 1/3 HAIs are preventable

Hospital Acquired Infections

Iatrogenic Infection: infection due to the activity of a physician or therapy


◦ Also termed a physician-acquired disease
◦ Ex: contaminated surgical instruments,


improper hand washing, improperly preparing skin for procedure

Hospital Acquired Infections

Cross Infection: infection transmitted from:


◦ patient to patient


◦ patient to medical personnel


◦ medical personnel to patient

Nosocomial Infections

Transmission Requires:


◦ microorganisms in hospital environment


◦ compromised host


◦ chain of transmission

Nosocomial Infections


Chain of Transmission

1. infectious agent


2. reservoir


3. portal of exit


4. mode of transmission


5. portal of entry


6. new (susceptible) host

Compromising Conditions

2 principle conditions that compromise a
patient:


◦ broken skin or mucous membrane


◦ suppressed immune system

Common Nosocomial Infections

◦ Urinary tract infections (34%)



◦ Surgical site infections (17%)



◦ ** Lower respiratory tract infections (13%)

Common Nosocomial Infections

◦ Bacteremia (14%)



◦ Others (22%)
-Skin infections, etc.



◦ benchmarking - best practice guidelines


◦ ex: pts should get meds 20mins prior to incision reduce chance of infection during sx

Common Nosocomial Agents

Frequently transmitted in respiratory equipment (we get blamed because bypass upper resp. tract where filtering of air happens so stays moist which attracts growth of bugs/bacteria)


- rod shaped


- gram negative

Common Nosocomial Agents

◦ Staphylococcus aureus
◦ Escherichia coli
◦ Streptococcus pneumoniae
◦ Clostridium difficile
◦ Pseudomonas aeruginosa

Preventing Nosocomial Infections

Infection control practices include:
◦ Routine practices
◦ Medical and surgical asepsis
◦ Proper hand washing
◦ Personal protective equipment
◦ Isolation techniques
◦ Sterilization and disinfection procedures

Universal Precautions

◦ Center for Disease Control (CDC) guidelines for health care workers regarding the prevention of disease transmission when handling patients and body substances



◦ Based on assumption that all patient specimens could harbor infectious agents**

Universal Precautions

◦ Attempt to ensure that carriers of bloodborne
pathogens (known and unrecognized) are


treated in a way which will prevent hospital-acquired infections in other patients and in


personnel



◦ developed in response to HIV

Elements of Routine Practices

◦ Environmental controls


◦ Administrative controls


◦ Risk assessment


◦ Hand hygiene


◦ Personal protective equipment (PPE)

Elements of Routine Practices


Environmental Controls

- patient placement


- environmental and equipment cleaning


- ventilation and air flow


- sharps and waste management

Elements of Routine Practices


Administrative Controls

- policies and procedures
- staff education
- healthy workplace policies
- immunization
- compliance monitoring with feedback
- sufficient staffing levels

Elements of Routine Practices


Risk Assessment

Performing a risk assessment will aid HCPs and other staff in choosing strategies for interaction, such as hand hygiene, use of PPE and specialized accommodation, which will reduce the risk of transmission of microorganisms to and from the client/patient/resident during the planned interaction

Elements of Routine Practices


Risk Assessment

- Will I be exposed to body fluids (e.g., blood, excretions, secretions) ?



If yes, PUT ON PPE AS INDICATED, OR maintain a spatial separation of at least two metres

Elements of Routine Practices


Risk Assessment

- Will my hands be exposed to blood, excretions, secretions or contaminated items?



If yes, WEAR GLOVES & PERFORM HAND
HYGIENE, OR maintain a spatial separation of at least two metres

Elements of Routine Practices


Risk Assessment

- Will my face be exposed to a splash, spray, cough or sneeze?



If yes, WEAR FACIAL PROTECTION, OR maintain a spatial separation of at least two metres

Elements of Routine Practices


Risk Assessment

- Will my clothing or skin be exposed to splashes/sprays or items contaminated with blood, excretions or secretions?



If yes, WEAR A If yes, WEAR A GOWN, OR GOWN, OR maintain a spatial separation of at least two metres

Elements of Routine Practices


Risk Assessment


Medical Asepsis

◦ Sepsis = presence of microorganisms



◦ Asepsis = absence of microorganisms



◦ Practiced by all hospital personnel



◦ Any measures used to prevent transfer of
microorganisms

Elements of Routine Practices


Risk Assessment


Medical Asepsis

◦ Techniques that reduce the # of microbes in the environment



◦ Exclusion or destruction of pathogens (endospores)



◦ Physical and chemical methods

Elements of Routine Practices


Risk Assessment


Surgical Asepsis

◦ Exclusion of all microbes in a specific area



◦ Performed prior to and during surgery and
other invasive procedures


◦ Disinfection of surgical space



◦ Sterilization of equipment

Elements of Routine Practices


Risk Assessment


Surgical Asepsis

◦ Preparation of patient’s skin prior to the first incision surgical “scrub”



◦ Sterile gowns and gloves



◦ Minimal traffic in operating suite

Elements of Routine Practices


Risk Assessment


Surgical Asepsis

**introduction of a surgical pause


- everybody stopping and talking about patient withoutdoing anything;


- happens 3 times


- first when patient is awake(surgical resident); turn over to anaestesia then nursing to discuss any concerns - patient gets to hear all of this (can confirm)

Elements of Routine Practices


Risk Assessment


Surgical Asepsis

- #2 happens before first incision; patient is asleep and is positioned;has had surgical scrub; pause and make sure on same page;


- #3 is before closing - count to make sure nothing is left inside body cavity; review what happened in sx, a lot can change from original plan- stolen from aircraft industries (pilots)

Elements of Routine Practices


Hand Hygiene

◦ Most significant means of reducing transmission rates***



◦ ~ 70% of preventable nosocomial infections
can be attributed to poor hand hygiene


◦ Also important in preventing cross


infections

Elements of Routine Practices


Hand Hygiene

Rationale for hand hygiene:
◦ removing or killing microbes on the hands


◦ maintaining good skin integrity (don't want hands to become portal of entry)



2 methods of hand hygiene:
◦ Soap and water (hand washing)
◦ Alcohol-based hand rubs

Elements of Routine Practices


Hand Hygiene

Alcohol-based hand rub:


◦ preferred method for cleaning hands


◦ better than washing hands (even with antibacterial soap) when hands are not visibly soiled.

Elements of Routine Practices


Hand Hygiene

Handwashing with soap and running water:


◦ must be done when hands are visibly soiled


◦ if running water is not available, use moistened towelettes to remove the visible soil, followed
by alcohol-based hand rub.

Elements of Routine Practices


Hand Hygiene


Alcohol-Based Hand Rub

◦ Preferred decontamination method when hands are NOT visibly soiled



◦ Rapid kill or removal of most transient bacteria



◦ Alcohol concentration range 60 – 90%

Elements of Routine Practices


Hand Hygiene


Alcohol-Based Hand Rub

◦ Contain emollients to prevent drying



◦ Quicker and more convenient

Elements of Routine Practices


Hand Hygiene


Regular Vs. Antibacterial Soap

Regular soap
◦ Appropriate in most situations
◦ No topping up from bulk container
◦ Bar soaps only appropriate for single patient
use

Elements of Routine Practices


Hand Hygiene


Regular Vs. Antibacterial Soap

Antibacterial Soap
◦ Used in critical care areas
◦ Used before surgical or invasive procedures
◦ Residual effect
◦ NOT recommended for routine use outside of healthcare settings

Elements of Routine Practices


Hand Hygiene


4 Moments of Hand Hygiene

1. before initial patient/patient environment contact


2. before aseptic procedures


3. after body fluid exposure risk


4. after patient/patient environment contact

Elements of Routine Practices


Hand Hygiene


Health Care Environment

Environment beyond the patient’s immediate area. In a single room this is outside the room. In a multiple room this is everything outside of
the patient’s bed area.

Elements of Routine Practices


Hand Hygiene


Patient Environment

This is the patient’s area. In a single room this is
everything in the patient’s room. In a multiple room this is everything in immediate proximity to the patient.

Elements of Routine Practices


Hand Hygiene


When to Perform

Before…
◦ Contact with patient
◦ Putting on gloves
◦ Performing invasive procedures
◦ Preparing, handling, serving food
◦ Feeding a patient
◦ Leaving the unit
◦ Eating

Elements of Routine Practices


Hand Hygiene


When to Perform

After…
◦ Care involving body fluids
◦ Visible soiling of the hands
◦ Any direct contact with patients or contaminated equipment
◦ Removing gloves
◦ Personal body functions

Elements of Routine Practices


Hand Hygiene


Hand Washing

Attention must be paid to:


◦ webs between fingers


◦ palms


◦ knuckles


◦ tips of fingers


◦ back of hands


◦ under fingernails

Elements of Routine Practices


Hand Hygiene


Hand Washing Techniques

1. Turn on taps.
2. Wet hands with warm water.
3. Apply liquid/foam soap.
4. Vigorously lather hands.
5. Thoroughly rinse soap from hands.
6. Dry hands thoroughly.
7. Turn off taps with paper towels.
8. Discard paper towel.

Elements of Routine Practices


Hand Hygiene


Moisturizing

◦ Important to maintain good skin integrity



◦ Recommended to moisturize frequently (6-10 times/shift) with hospital provided product


- wont break down gloves


- oil/scent free


- cross contamination if bringing from home

Elements of Routine Practices


PPE

◦ PPE does not replace the need for hand hygiene



◦ Only effective when applied, used, removed and disposed of properly

Elements of Routine Practices


PPE

PPE used to:
◦ Prevent contact with non-intact skin, blood, body fluids, excretions and secretions
◦ Prevent the spread of pathogens via the contact, droplet or airborne route
◦ Prevent transmission between patients

Elements of Routine Practices


PPE

Includes:


◦ gloves


◦ gowns


◦ face protection


◦ goggles


◦ masks


◦ shields


◦ HEPA filter

Elements of Routine Practices


PPE


Gloves

◦ Worn to provide an additional barrier between
health care worker’s hands and bodily fluids, etc.



◦ Reduce transmission between:


- infected patients to HCWs


- patient to patient via HCW's hands

Elements of Routine Practices


PPE


Gloves

Should be removed and hands washed…
◦ Promptly after use and before moving to
another patient
◦ If gloves leak or tear
◦ When moving from a contaminated body site
to an uncontaminated area

Elements of Routine Practices


PPE


Glove Selection

The barrier integrity of gloves varies based on:
◦ type and quality of glove material
◦ intensity of use
◦ length of time used
◦ manufacturer
◦ whether gloves were tested before or after use
◦ method used to detect glove leaks

Elements of Routine Practices


PPE


Glove Selection

Glove selection is task specific:


◦ Vinyl
- Appropriate for most patient care activities



◦ Nitrile
- Used for higher risk procedures, chemical handling

Elements of Routine Practices


PPE


Glove Selection

Glove selection is task specific:


◦ Latex/neoprene
- Used for sterile procedures

Elements of Routine Practices


PPE


Gowns

◦ Protective barrier from blood and bodily fluids



◦ Protect skin and soiling of clothing



◦ Removed immediately when wet or soiled

Elements of Routine Practices


PPE


Gowns

◦ Never reused, even on the same patient


◦ Can be disposed of with dirty linen or


biohazardous waste

Elements of Routine Practices


PPE


Gowns

Selection is again task dependent:
◦ Yellow gowns (paper or fabric)
- Used with additional precautions or as per routine practice



◦ Blue poly-coated gown
- Used for handling chemicals (e.g. chemotherapeutic agents)

Elements of Routine Practices


PPE


Gowns

Selection is again task dependent:


◦ Goretex gown
- Worn when contact with bodily fluids/tissue
anticipated (e.g., during surgery)

Elements of Routine Practices


PPE


Face Protection

◦ Barrier protection during procedures likely to
generate splashes, or sprays of blood, bodily
fluids, secretions or excretions



◦ Protects eyes, nose and mouth (mucous
membranes)

Elements of Routine Practices


PPE


Face Protection

◦ Removed immediately if it becomes moist



◦ Remove upon exiting patient environment

◦ Eye glasses do not replace face shields/goggles



◦ Can be disposed of in garbage or with
biohazardous waste

Elements of Routine Practices


PPE


Donning (Putting On)

1. Hand hygiene
2. Gown
3. Mask/respirator
4. Eye protection
5. Gloves

Elements of Routine Practices


PPE


Doffing (Taking Off)

1. Gloves


2. Gown


3. Hand hygiene


4. Mask/eye protection


5. Hand hygiene

Elements of Routine Practices


PPE


HEPA Filter

High Efficiency Particulate Air Filter



◦ Filters 97% of particulate matter from the
air
- Particles 0.3 µm or larger in diameter



◦ Used in operating rooms, isolation units,
laboratories

Isolation Techniques

Forward Isolation
◦ Infectious patients



◦ Protect HCW, visitors from becoming infected



◦ PPE worn when entering room



◦ PPE disposed of in receptacle when leaving

Isolation Techniques

Forward Isolation


◦ Equipment disinfected or placed in closed
container



◦ Negative air pressure



◦ Exhaust air through HEPA filters

Isolation Techniques

Reverse Isolation
◦ Compromised patients



◦ Same gowning, gloving, masking procedures as
with forward isolation

Isolation Techniques

Reverse Isolation


◦ Positive air pressure



◦ Incoming air through HEPA filters



◦ If severely compromised (e.g., burn patient),
enclosed completely

Contact Precautions

◦ Patients suspected of being infected with
microbes spread by direct contact with the
patient, environment or patient care items

Contact Precautions

◦ Gowns, gloves, private room or cohort with like
patients



◦ Dedicated equipment (or wiped between
patients)

Contact Precautions

Antibiotic Resistant Organisms


- MRSA


- VRE


- C-Diff


- uncontained drainage,diarrhea


- impetigo


- scabies

Antibiotic Resistant Organisms


MRSA


Impact

◦ Greater morbidity and mortality



◦ Increased hospitalization and supportive care

Antibiotic Resistant Organisms


MRSA


Impact

Increased use of resources:
◦ Laboratory and diagnostic tests
◦ Infection control procedures/ equipment
◦ More expensive treatment agents
◦ Length of hospital stay and lost work days

Antibiotic Resistant Organisms


MRSA


Canada

◦ 50% increase in MRSA from 2004 to 2007



◦ Ontario 10,301 pts with MRSA reported
in 2004 with 16,498 in 2007



◦ Just because acquire MRSA doesn't mean will contract

Antibiotic Resistant Organisms


MRSA


Canada

72% reported as hospital acquired
◦ 15% in nursing homes
◦ 13% community acquired
◦ 30% reported as infected versus colonized

Antibiotic Resistant Organisms


MRSA


Cost

◦ MRSA costs in Canada estimated at $129
million (2010)


◦ $12,216 per patient with MRSA infection
◦ 81% Hospitalization, $9894 ($2400/day if ICU)
◦ 13% Barrier protection, $1588
◦ 4% Antibiotics, $488
◦ 2% Lab investigations, $244

Antibiotic Resistant Organisms


C-Diff

◦ Superinfection


◦ Resident flora of intestinal tract



◦ Very resistant to antibiotics, can multiply while other microbes are destroyed

Antibiotic Resistant Organisms


C-Diff

◦ Causes severe form of diarrhea, colitis



◦ Potentially fatal

Contact Precautions

◦ Gloves required for direct care



◦ Long-sleeved gown required for direct care when skin or clothing may become contaminated



◦ Use dedicated equipment or disinfect before use with another patient

Airborne Precautions

◦ Patients known or suspected to be infected with pathogens transmitted by airborne droplet nuclei (<5 um)


◦ Small particles remain suspended in air for long periods of time; disperse in air currents

Airborne Precautions

◦ Infectious agents:
- TB, varicella virus, rubeola, SARS



◦ Staff must be fit tested for a N95 respirator

Airborne Precautions

◦ Pt wears procedure mask outside room



◦ Negative pressure inside pt room


- CSA standard 12 room air exchanges per hour

Droplet Precautions

◦ Patients suspected of being infected with microbes transmitted by droplets (>5um)



◦ Larger droplets fall to environmental surfaces



◦ Infectious agents:
- Pneumonia (known etiology), meningococcal
disease, rubella, pertussis

Droplet Precautions

◦ Surgical masks and eye protection if within 2m of patient



◦ Gloves for direct patient contact



◦ Private room or cohort



◦ Pt wears procedure mask outside room

Droplet and Contact Precautions

◦ Microbes can exhibit more than one mode of transmission



◦ Incorporates both droplet and contact
precautions

Droplet and Contact Precautions

Common indications:
• Viral respiratory illness (e.g., influenza, RSV)



• Meningitis:
- etiology unknown pediatric

Droplet and Contact Precautions

• Group A Streptococcus (GAS):
- toxic shock-like syndrome
- skin, wound or burn infection



• Pneumonia etiology unknown



• Necrotizing fasciitis

Droplet and Contact Precautions

◦ Procedure/surgical mask and protective eyewear required within 2m



◦ Gloves required for all patient/patient environment contact



◦Lon-sleeved gown required in skin or clothing will contact patient/patient environment

Droplet and Contact Precaution

◦ Patient to wear a procedure/surgical mask for transport



◦ Use dedicated equipment or disinfect before use with another patient