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89 Cards in this Set

  • Front
  • Back
All cancers metastasize to the lymph nodes except 1________, 2________
Brain, Uterus
Uterine cancer metastasis sites
1_________, 2__________
Bone, Peritoneum
Each of these 6 kinds of cancer have at least 6 sites of metastasis.,
Breast, Cervix, Leukemia, Lymphoma, Lung, Melanoma
Breast cancer metastasis sites
Bone, bone marrow, lung, liver, nodes, brain
Brain cancer metastasis sites
Only to brain
Prostate cancer metastasis sites 5of them
Bone, bone marrow, lung, liver, nodes
Melanoma metastasis sites 7 of them
Bone, bone marrow, skin, lung, liver, nodes, brain
Leukemia/lymphoma metastasis sites 6 of them
Bone, bone marrow, skin, lung, nodes, brain
Cancers that spread to the brain 5 of them
Breast, kidney, leukemia/lymphoma lung, melanoma
Cancers that spread to the bone
11 of them
Breast, cervix, esophagus, liver, kidney, lung, melanoma, prostate, stomach, testes, thyroid
Cancers that spread to the liver 13 of them
Breast, cervix colon, esophagus, kidney, lung, melanoma, ovary, pancreas, prostate, sarcoma, stomach, testes
Signs and symptoms of advanced cancer
Weakness, anorexia, cachexia, pain, nausea, constipation/diarrhea, dyspnea, edema, change in LOC, confusion, agitation, infections
Cancers that are most likely to be fatal 6 of them
Esophagus, Lung, Liver, Pancreas, Ovarian, Multiple myeloma
Angiogenesis
Generation of blood vessels around the primary tumor that increases chance for tumor cells to reach blood stream and colonize
Oncologic emergencies and complications
Spinal cord compression,
Intracerebral metastases,
Syndrome of inappropriate antidiuretic hormone (SIADH),
Hypercalcemia,
Hemorrhage,
cardiac tamponade,
superior vena cava syndrome,
DIC,
Bowel obstruction,
Septic shock,
Tumor lysis syndrome,
Anaphylaxix
spinal cord compression symptoms
localized back pain, motor deficits, sensory deficits paresthesia, bowel and bladder inc, bladder retention
Spinal cord compression treatments
Steroids high doses, Radiation, stabilization surgery,
Needs emergency treatment to prevent permanent damage. If pt is candidate for tx.
Intracerebral metastases signs and symptoms
causes increased ICP, early morning headache, confusion, agitation, projectile vomiting, cognitive dysfunction
Syndrome of inappropriate antidiuretic hormone symptoms:
weight gain, Hyponatremia
nausea, vomiting, altered mood, weak, lethargic, confused, muscle cramps, loss of consciousness.
Syndrome of inappropriate antidiuretic hormone treatment:
Fluid restriction, furosemide, hypertonic saline, Demeclocycline
Hypercalcemia signs & symptoms
Calcium greater than 11 mg/dl nausea, vomiting, anorexia, constipation, lethargy, confusion, polyuria, stupor, coma, mental status changes, polydipsia
Hypercalcemia treatments
Hydratrioon, Furosemide, if has fluid retention, steroids
Hemmorhage signs and symptoms
Tumor erosion or invasion near major blood vessel, oozing or bleeding, anxiety, decreased blood pressure, respiratory distress
Hemmorhage treatment
Prepare and support family, dark towels and sheets, pain medication, treat oozing with topical epinephrine
Cardiac Tamponade Signs and symptoms
muffled heart sounds, pericardial rub, tachycardia, pulsus paridoxux, dyspnea, cough, dysphagia, retrosternal chest pain, hoarseness, increased jugular venous pressure
Cardiac Tamponade Treatment
Anxiolytics, Oxygen, pericardiocentesis, radiation
Causes of
Superior Vena Cava Syndrome
Cancer of lung, breast, lymphoma, brain tumors, blood clots in SVC, Infections, TB,Edema, STD, sarcoidosis
Superior vena cava syndrome
signs and symptoms
edema of face, trunk, and upper extremities; distended veins in neck, headache, chest pain, visual and mental changes, dizziness, dry cough
Superior vena cava syndrome
Treatments
Depend on the cause of SVCS Steroids, Furosemide, radiation, chemo, warfarin, elevate HOB
DIC disseminated intravascular coagulation signs and symptoms
bleeding, clotting, dyspnea, restlessness, tachycardia, petechiae, purpura, altered LOC
DIC disseminated intravascular coagulation Treatments
Hydration, Oxygen, anxiolytics (lorazepam), heparin, antithrombin II treat malignacy, blood component therapy
Large bowel obstruction
signs and symptoms
Crampy pain lower abdomen that increases over time. Vomiting a late sign, constipation, abdominal distention, abnormal bowel sounds
Large bowel obstruction
Treatments
Pain control, anti nausea, anxiolytics, glycopyrrolate, Octreotide, stent, IV therapy, surgery
Small bowel obstruction
signs and symptoms
Crampy colicky pain in mid to upper abdomen relieved by vomiting
Small bowel obstruction
Treatments
Pain control, anti nausea, anxiolytics, NG suction, stent, IV therapy, surgery
bowel strangulation
signs and symptoms
severe steady abdominal pain
bowel strangulation Treatments
surgery, antibiotics NG tube
Palliative surgery
bone stabilization, relieve bowel obstruction, place stents, pain management, tumor debulking,
Relief of symptoms without a goal of curing the disease
Palliative radiation therapy
relieves symptoms including pain, bleeding, compression of vital organ systems, ulcerating skin lesions, skeletal and brain mets, spinal cord compression, SVCS,
ILEUS what is it and signs/symptoms
It is paralyzed intestines,
Moderate diffuse abdominal pain constipation, abdominal distension, No BM, NO Gas, Nausea, vomiting, belching
ILEUS treatment
NPO, lactulose, electrolytes

can be caused by opiods, peritonitis, spinal cord injury
Constipation caused by what medications
Opiods, tricyclic antidepressants, phenothiazines, antacids, diuretics, iron, vincristine, anti-hypertensives, anticonvulsants, anticolinergices, NSAIDs ***Discontinue any of these meds that are not needed.
Constipation caused by what diseases and disorders
Obstruction, abdominal tumors , Colitis, diverticular disease, diabetes, hypercalcemia, hypokalemia, hypothyroidism
Constipation caused by what life-style choices and neurological changes
Low fiber intake, insufficient fluid intake, inactivity, immobility, confusion, depression, sedation
Other causes of constipaiton
Pain from hemorrhoids and other rectal pain, embarrassment, loss of independence.
Digital disimpation contraindicated in
Lower GI bleed, thrombocytopenic patients, neutorpenic patients, end stage cardiac
Constipation signs and symptoms
Distension, tenderness, bloated, bowel sounds normal of hypo-active; percussion reveals unusual dullness, may be able to palpate stool in bowel
Medication used for severe opioid related constipation
Methylnaltrexone (Relistor) works in less than an hour, reverses the effect of opioid only on the bowel not pain control
Titrate laxatives
When changing opioid dosing, should be scheduled not PRN
SennaS has both softener and stimulant.
If no bowel movement in 3 days
increase fluids order osmotic laxative
Osmotic Laxatives include
MOM
Lactulose (use this if liver is involved)
Sorbitol
Miralax
Bowel obstruction or impaction can surprisingly cause
Diarrhea
Stage I Decubitus
Reddened intact skin, does not blanch when pressure applied, may be painful, may be warmer, cooler, and or a different texture from other skin. Dark skinned people it will not appear reddened it will appear darker
Stage II Decubitus
Partial thickness skin loss, shallow looks like a blister, abrasion
Stage III Decubitus
Full thickness skin loss with or without damage to subcutaneous tissue or undermining
Stage IV Decubitus
Full thickness skin loss deep damage extends to muscle, tendons even to bone. often has tunneling
Evaluate pressure areas for
Size, depth, color, tissue type, odor, exudate (quantity and color)
Xerostomia treatments

Dry Mouth
Change medications (if on meds that dry the mucous membranes);
Stimulate salivation, peppermint water, sugar free hard candy, ice chips, gum, no lemon or vitamin C;
Treat dehydration, increase fluids, toothettes, ice chips
Artificial saliva
Xerostomia causes

Dry mouth
Dehydration caused by poor intake of fluids or other disease process such as:Hypercalcemia, hyperglycemia ,
mouth breathing,
Medications and treatments: Anticholinergics, antihistamines, phenothiazines, radiation, chemotherapy,
,
Nociceptic Pain
Somatic or visceral pain, Pain that is not neuropathic
Neuropathic Pain
Symptoms
Shooting, burning
may also have tingling and numbness
Somatic Pain
Well localized pain described as deep dull ache, Musculoskeletal in nature controlled with NSAIDS if mild, opiates if severe
Visceral Pain
Pain that is poorly localized cramping, often referred to distant dermatomal site. Controlled with analgesics antispasmodics, antineoplastics, examples: bowel obstruction, lung tumors, cholesystitis, angina
Dysthesia
unpleasant abnormal sensation
Hyperalgesia
Painful syndrome Abnormally painful reaction to a normally non painful stimulus such as touch.
Allodynia
Pain due to stimulus which does not normally cause pain such as sensitivity to touch.
Neuralzia
Pain in the distribution of a nerve or nerves.
Septic shock
cause
toxins in the blood cause Cardiovascular collapse
Septic shock
signs and symptoms
fever chills skin starts warm becomes cold and clammy, hypotension, mental status changes, oliguiria
Septic shock
treatment
Antibiotics, oxygen, fluid replacement 2 liters before vasoconstrictive meds given, vasoconstrictive medications
Anaphylaxis
signs and symptoms
rsspiratory distress, hypertension, fainting, itching, bradycardia, tachycardia, and respiratory arrest
Anaphylaxis
Treatment
Emergency!
Epinephrine, Diphenhydramine, hydrocortisone, keep airway open
Parkinson's disease symptoms
Tremor, loss of control of voluntary muscle movements, & rigidity, also may include anxiety, confusion, constipation, and dementia
Left sided CHF presents with
Congested lungs. Anxiety, restlessness, dyspnea, orthopnea, cough, tachycardia, palpitations, rales in lower lobes, wheezes in bronchi, fatigue, cyanosis
Right sided CHF presents with
Liver and lower extremities poor blood return. Anorexia, nausea weight gain, Dependent, peripheral edema, weakness, nocturia, oliguria
COPD with Emphysema
Thin wasted muscles, barrel chest, weak cough, use accessory muscles to breathe, diminished breath sounds
COPD with chronic bronchitis
Over weight, central cyanosis, Wheezes, little use of accessory muscles
COPD
Treatment
Bronchodilatiors, corticosteroids, anticholiergics, xanthines, antibiotics, Oxygen if desired
Restrictive Lung diseases
Examples
Tumors, effusions, diseases that reduce the ability for lungs to expand: myasthenia gravis, diffuse idiopathic interstitial fibrosis,
Restrictive Lung diseases
treatments
corticosteroids, nebulizers, oxygen, antibiotics if desired
Renal Failure
Lab value signs
BUN and creatinine rise, GFR <15
can be oliguric or not
Gancyclovir
Used to prevent CMV retinitis/blindness until final stages of AIDS
HAART
Highly active antiretroviral therapy-use of 3 or 4 antiretroviral drugs taken in combination has increased survival and quality or life for HIV patients now more chronic disease than terminal.
Asterixis
Liver flap hand can not stay up tremors and comes down i a few seconds.
Medications for Pneumocyctis Carini Pneumonia
Clotirimoxazole, pentamidine, trimetrexate, dapsone, bactrim,
Bactrim may be used prophalactically.
Glycopyrrolate
Robinul decreases secretions, Anticholiergic/antimuscarinic
Used for bowel obstructions
Octreotide
sandostatin, injectable antidiarrheal decreases motility
Naloxone
Narcan counteracts opioid overdose
Ondansetron
Zofran treats Nausea and vomiting caused by chemo also used for liver related uremic and opioid induced pruritis
Common Antimuscarinic/Antichoinergic meds
Loperimide, scopalamine, atropine, glycoyrrolate (Robinol)