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89 Cards in this Set
- Front
- Back
All cancers metastasize to the lymph nodes except 1________, 2________
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Brain, Uterus
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Uterine cancer metastasis sites
1_________, 2__________ |
Bone, Peritoneum
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Each of these 6 kinds of cancer have at least 6 sites of metastasis.,
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Breast, Cervix, Leukemia, Lymphoma, Lung, Melanoma
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Breast cancer metastasis sites
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Bone, bone marrow, lung, liver, nodes, brain
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Brain cancer metastasis sites
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Only to brain
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Prostate cancer metastasis sites 5of them
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Bone, bone marrow, lung, liver, nodes
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Melanoma metastasis sites 7 of them
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Bone, bone marrow, skin, lung, liver, nodes, brain
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Leukemia/lymphoma metastasis sites 6 of them
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Bone, bone marrow, skin, lung, nodes, brain
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Cancers that spread to the brain 5 of them
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Breast, kidney, leukemia/lymphoma lung, melanoma
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Cancers that spread to the bone
11 of them |
Breast, cervix, esophagus, liver, kidney, lung, melanoma, prostate, stomach, testes, thyroid
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Cancers that spread to the liver 13 of them
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Breast, cervix colon, esophagus, kidney, lung, melanoma, ovary, pancreas, prostate, sarcoma, stomach, testes
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Signs and symptoms of advanced cancer
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Weakness, anorexia, cachexia, pain, nausea, constipation/diarrhea, dyspnea, edema, change in LOC, confusion, agitation, infections
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Cancers that are most likely to be fatal 6 of them
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Esophagus, Lung, Liver, Pancreas, Ovarian, Multiple myeloma
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Angiogenesis
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Generation of blood vessels around the primary tumor that increases chance for tumor cells to reach blood stream and colonize
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Oncologic emergencies and complications
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Spinal cord compression,
Intracerebral metastases, Syndrome of inappropriate antidiuretic hormone (SIADH), Hypercalcemia, Hemorrhage, cardiac tamponade, superior vena cava syndrome, DIC, Bowel obstruction, Septic shock, Tumor lysis syndrome, Anaphylaxix |
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spinal cord compression symptoms
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localized back pain, motor deficits, sensory deficits paresthesia, bowel and bladder inc, bladder retention
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Spinal cord compression treatments
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Steroids high doses, Radiation, stabilization surgery,
Needs emergency treatment to prevent permanent damage. If pt is candidate for tx. |
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Intracerebral metastases signs and symptoms
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causes increased ICP, early morning headache, confusion, agitation, projectile vomiting, cognitive dysfunction
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Syndrome of inappropriate antidiuretic hormone symptoms:
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weight gain, Hyponatremia
nausea, vomiting, altered mood, weak, lethargic, confused, muscle cramps, loss of consciousness. |
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Syndrome of inappropriate antidiuretic hormone treatment:
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Fluid restriction, furosemide, hypertonic saline, Demeclocycline
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Hypercalcemia signs & symptoms
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Calcium greater than 11 mg/dl nausea, vomiting, anorexia, constipation, lethargy, confusion, polyuria, stupor, coma, mental status changes, polydipsia
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Hypercalcemia treatments
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Hydratrioon, Furosemide, if has fluid retention, steroids
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Hemmorhage signs and symptoms
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Tumor erosion or invasion near major blood vessel, oozing or bleeding, anxiety, decreased blood pressure, respiratory distress
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Hemmorhage treatment
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Prepare and support family, dark towels and sheets, pain medication, treat oozing with topical epinephrine
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Cardiac Tamponade Signs and symptoms
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muffled heart sounds, pericardial rub, tachycardia, pulsus paridoxux, dyspnea, cough, dysphagia, retrosternal chest pain, hoarseness, increased jugular venous pressure
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Cardiac Tamponade Treatment
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Anxiolytics, Oxygen, pericardiocentesis, radiation
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Causes of
Superior Vena Cava Syndrome |
Cancer of lung, breast, lymphoma, brain tumors, blood clots in SVC, Infections, TB,Edema, STD, sarcoidosis
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Superior vena cava syndrome
signs and symptoms |
edema of face, trunk, and upper extremities; distended veins in neck, headache, chest pain, visual and mental changes, dizziness, dry cough
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Superior vena cava syndrome
Treatments |
Depend on the cause of SVCS Steroids, Furosemide, radiation, chemo, warfarin, elevate HOB
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DIC disseminated intravascular coagulation signs and symptoms
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bleeding, clotting, dyspnea, restlessness, tachycardia, petechiae, purpura, altered LOC
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DIC disseminated intravascular coagulation Treatments
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Hydration, Oxygen, anxiolytics (lorazepam), heparin, antithrombin II treat malignacy, blood component therapy
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Large bowel obstruction
signs and symptoms |
Crampy pain lower abdomen that increases over time. Vomiting a late sign, constipation, abdominal distention, abnormal bowel sounds
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Large bowel obstruction
Treatments |
Pain control, anti nausea, anxiolytics, glycopyrrolate, Octreotide, stent, IV therapy, surgery
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Small bowel obstruction
signs and symptoms |
Crampy colicky pain in mid to upper abdomen relieved by vomiting
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Small bowel obstruction
Treatments |
Pain control, anti nausea, anxiolytics, NG suction, stent, IV therapy, surgery
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bowel strangulation
signs and symptoms |
severe steady abdominal pain
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bowel strangulation Treatments
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surgery, antibiotics NG tube
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Palliative surgery
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bone stabilization, relieve bowel obstruction, place stents, pain management, tumor debulking,
Relief of symptoms without a goal of curing the disease |
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Palliative radiation therapy
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relieves symptoms including pain, bleeding, compression of vital organ systems, ulcerating skin lesions, skeletal and brain mets, spinal cord compression, SVCS,
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ILEUS what is it and signs/symptoms
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It is paralyzed intestines,
Moderate diffuse abdominal pain constipation, abdominal distension, No BM, NO Gas, Nausea, vomiting, belching |
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ILEUS treatment
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NPO, lactulose, electrolytes
can be caused by opiods, peritonitis, spinal cord injury |
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Constipation caused by what medications
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Opiods, tricyclic antidepressants, phenothiazines, antacids, diuretics, iron, vincristine, anti-hypertensives, anticonvulsants, anticolinergices, NSAIDs ***Discontinue any of these meds that are not needed.
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Constipation caused by what diseases and disorders
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Obstruction, abdominal tumors , Colitis, diverticular disease, diabetes, hypercalcemia, hypokalemia, hypothyroidism
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Constipation caused by what life-style choices and neurological changes
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Low fiber intake, insufficient fluid intake, inactivity, immobility, confusion, depression, sedation
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Other causes of constipaiton
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Pain from hemorrhoids and other rectal pain, embarrassment, loss of independence.
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Digital disimpation contraindicated in
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Lower GI bleed, thrombocytopenic patients, neutorpenic patients, end stage cardiac
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Constipation signs and symptoms
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Distension, tenderness, bloated, bowel sounds normal of hypo-active; percussion reveals unusual dullness, may be able to palpate stool in bowel
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Medication used for severe opioid related constipation
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Methylnaltrexone (Relistor) works in less than an hour, reverses the effect of opioid only on the bowel not pain control
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Titrate laxatives
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When changing opioid dosing, should be scheduled not PRN
SennaS has both softener and stimulant. |
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If no bowel movement in 3 days
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increase fluids order osmotic laxative
Osmotic Laxatives include MOM Lactulose (use this if liver is involved) Sorbitol Miralax |
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Bowel obstruction or impaction can surprisingly cause
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Diarrhea
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Stage I Decubitus
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Reddened intact skin, does not blanch when pressure applied, may be painful, may be warmer, cooler, and or a different texture from other skin. Dark skinned people it will not appear reddened it will appear darker
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Stage II Decubitus
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Partial thickness skin loss, shallow looks like a blister, abrasion
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Stage III Decubitus
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Full thickness skin loss with or without damage to subcutaneous tissue or undermining
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Stage IV Decubitus
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Full thickness skin loss deep damage extends to muscle, tendons even to bone. often has tunneling
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Evaluate pressure areas for
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Size, depth, color, tissue type, odor, exudate (quantity and color)
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Xerostomia treatments
Dry Mouth |
Change medications (if on meds that dry the mucous membranes);
Stimulate salivation, peppermint water, sugar free hard candy, ice chips, gum, no lemon or vitamin C; Treat dehydration, increase fluids, toothettes, ice chips Artificial saliva |
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Xerostomia causes
Dry mouth |
Dehydration caused by poor intake of fluids or other disease process such as:Hypercalcemia, hyperglycemia ,
mouth breathing, Medications and treatments: Anticholinergics, antihistamines, phenothiazines, radiation, chemotherapy, , |
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Nociceptic Pain
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Somatic or visceral pain, Pain that is not neuropathic
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Neuropathic Pain
Symptoms |
Shooting, burning
may also have tingling and numbness |
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Somatic Pain
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Well localized pain described as deep dull ache, Musculoskeletal in nature controlled with NSAIDS if mild, opiates if severe
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Visceral Pain
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Pain that is poorly localized cramping, often referred to distant dermatomal site. Controlled with analgesics antispasmodics, antineoplastics, examples: bowel obstruction, lung tumors, cholesystitis, angina
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Dysthesia
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unpleasant abnormal sensation
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Hyperalgesia
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Painful syndrome Abnormally painful reaction to a normally non painful stimulus such as touch.
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Allodynia
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Pain due to stimulus which does not normally cause pain such as sensitivity to touch.
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Neuralzia
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Pain in the distribution of a nerve or nerves.
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Septic shock
cause |
toxins in the blood cause Cardiovascular collapse
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Septic shock
signs and symptoms |
fever chills skin starts warm becomes cold and clammy, hypotension, mental status changes, oliguiria
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Septic shock
treatment |
Antibiotics, oxygen, fluid replacement 2 liters before vasoconstrictive meds given, vasoconstrictive medications
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Anaphylaxis
signs and symptoms |
rsspiratory distress, hypertension, fainting, itching, bradycardia, tachycardia, and respiratory arrest
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Anaphylaxis
Treatment |
Emergency!
Epinephrine, Diphenhydramine, hydrocortisone, keep airway open |
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Parkinson's disease symptoms
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Tremor, loss of control of voluntary muscle movements, & rigidity, also may include anxiety, confusion, constipation, and dementia
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Left sided CHF presents with
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Congested lungs. Anxiety, restlessness, dyspnea, orthopnea, cough, tachycardia, palpitations, rales in lower lobes, wheezes in bronchi, fatigue, cyanosis
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Right sided CHF presents with
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Liver and lower extremities poor blood return. Anorexia, nausea weight gain, Dependent, peripheral edema, weakness, nocturia, oliguria
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COPD with Emphysema
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Thin wasted muscles, barrel chest, weak cough, use accessory muscles to breathe, diminished breath sounds
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COPD with chronic bronchitis
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Over weight, central cyanosis, Wheezes, little use of accessory muscles
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COPD
Treatment |
Bronchodilatiors, corticosteroids, anticholiergics, xanthines, antibiotics, Oxygen if desired
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Restrictive Lung diseases
Examples |
Tumors, effusions, diseases that reduce the ability for lungs to expand: myasthenia gravis, diffuse idiopathic interstitial fibrosis,
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Restrictive Lung diseases
treatments |
corticosteroids, nebulizers, oxygen, antibiotics if desired
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Renal Failure
Lab value signs |
BUN and creatinine rise, GFR <15
can be oliguric or not |
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Gancyclovir
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Used to prevent CMV retinitis/blindness until final stages of AIDS
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HAART
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Highly active antiretroviral therapy-use of 3 or 4 antiretroviral drugs taken in combination has increased survival and quality or life for HIV patients now more chronic disease than terminal.
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Asterixis
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Liver flap hand can not stay up tremors and comes down i a few seconds.
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Medications for Pneumocyctis Carini Pneumonia
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Clotirimoxazole, pentamidine, trimetrexate, dapsone, bactrim,
Bactrim may be used prophalactically. |
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Glycopyrrolate
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Robinul decreases secretions, Anticholiergic/antimuscarinic
Used for bowel obstructions |
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Octreotide
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sandostatin, injectable antidiarrheal decreases motility
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Naloxone
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Narcan counteracts opioid overdose
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Ondansetron
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Zofran treats Nausea and vomiting caused by chemo also used for liver related uremic and opioid induced pruritis
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Common Antimuscarinic/Antichoinergic meds
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Loperimide, scopalamine, atropine, glycoyrrolate (Robinol)
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