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107 Cards in this Set
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Herbs (botanical)
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nonwoody plant
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Herbs (culinary)
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leafy parts found in temperate climates
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Spices
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non leaf organs of plants typically from tropical climates
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Medicinal plants
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plants that are valued for their physiological, therapeutic, or psychoactive effects
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Difference between herbs and spices
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herbs are leafy and found in temperate climates, spices are not the leaves and found in tropical climates
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Five tropical spices from early Europe and Far East
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Cinnamon, black pepper, nutmeg, cloves, ginger
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Two anti-cancer drugs we discussed during random screening section
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* Madagascar Periwinkle – vincristine and vinblastine alkaloids
* Pacific Yew (Pacific Northwest) – bark has paclitaxil, interferes with microtubule cell division, Taxol |
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Opium Poppy
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morphine/codeine; analgesic (pain reliever); immature fruit capsule
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Coca
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cocaine/novacaine; stimulant and anesthetic(relieved thirst, hunger, and fatigue); leaves
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Willows
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aspirin; pain reliever/reduce fever/reduce inflammation; bark and root
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Foxglove
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digitoxin/digioxin/digitalis; treatment for dropsy edema (stimulates heart beat); leaves
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Methods for searching for Medicines
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* Taxonomic targeting
* Ecological targeting * Ethnobotanical * Zoopharmacognasy |
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Taxonomic targeting
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Finding plants that are in the same family as already known effective plants
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Ecological targeting
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Finding plants that are similar that are know tow be useful, like vines
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Ethnobotanical
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relationships between plants and people. Finding medicines from local people and how they use the plants
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Zoopharmacognasy
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learning from how animals use the plants to find possible uses
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Tropane alkaloids
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Scopolamine
Cocaine Hyoscyamine Scopolamine |
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Coca (alkaloids)
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Cocaine
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Opium Poppy (alkaloids)
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Morphine, Codeine
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Willow (alkaloids)
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Salicin
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Mandrake (alkaloids)
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Hyoscyamine
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Ebers Papyrus
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Egyptian document that is 65ft long and contains over 700 recipes for herbal treatments
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Spice Islands
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Islands in south east Asia, including the Indonesian Islands, that a lot of old world spices came from
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Arils
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fleshy appendage that is attached to a seed to facilitate dispersal (like attracting birds)
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Panacea
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a cure all (also the Greek goddess of Healing)
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Analgesic
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pain killer
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William Withering
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wrote about foxglove and was the first to use systematic experimentation (treated dropsy or lymph edema)
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Doctrine of Signatures
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idea that clues about the use of a plant could be revealed by the shape, taste, texture, and color
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Officinale
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is used at the species names for a medicinal plant
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Queen Hatshepsut
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first botanical collecting expedition to the land of punt; returned with myrrh
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Rhizome
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underground stem
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Peyote
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cactus that looks like an above ground button and has colorful showy flowers; it is a psychoactive drug and it is used by native Americans in religious ceremonies
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Taxol
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anti-cancer drug made from Paclitaxel, which is a mitotic inhibitor.
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Hexing herbs
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herbs used by witches
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Glucosinolates
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compounds that combine with enzymes to produce isothiocyanates and creates that “hot” sensation in many foods (like wasabi)
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Malabar Coast
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the SW part of what is now India and surrounding was an essential part of the Old world spice trade and is where black pepper originates
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Henbane
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poisonous plant that was one of the hexing herbs along with mandrake and datura; causes hallucinations, restlessness, dilated pupils
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Carminative
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relieves or prevents gas (Cardamom seeds)
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Capsaicin
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compound responsible for heat and is concentrated in the placenta
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Culinary
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used for cooking
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Scoville scale
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scale of heat based on how much the item had to be diluted before the heat was undetectable
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Curry powder
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an Indian mix of spices that varies based on the recipe, but often include coriander, turmeric, cumin
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Bioassay
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measure the effects of a substance on a living organism
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Hemiparasite
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plant that is parasitic under natural conditions and is also photosynthetic to some degree and may just obtain water and mineral nutrients from the host plant (mistletoe)
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Voucher specimen
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a specimen that is kept on hand for identification (so you know what it looks like)
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Garam Masala
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Spicy Indian paste that uses ingredients like blackpeppercorns, cloves, cumin seeds, and cardamom
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Myrrh
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scented substance that comes from trees and is used as incense
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Tussie mussie
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small bunch of flowers, typically given as a gift worn around the head or bodice to mask the unpleasant smells of the time (medieval)
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Dioecious
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separate male and female plants
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Ayahuasca
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religious psychoactive plant that comes from tropical vines
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Native American Church
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believe God’s spirit is in peyote. It is infused with Christianity and is native to the Rio Grande valley
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Dropsy
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abnormal accumulation of fluid beneath the skin, and is referred to as edema in modern medicine
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Brugmansia
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Angels Trumpet long-lived, woody trees or bushes, with pendulous, not erect, flowers, that have no spines on their fruit. Datura species are herbaceous bushes with pendulous (not erect) flowers, and most have spines on their fruit. Found in South America and is highly toxic (tropane alkaloids)
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Three Herbs Egyptians used in preparation of mummies
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Cumin, anise, marjoram, cinnamon, myrrh, an frankincense
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How is frankincense harvested?
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scraping the bark and allowing the exuded resins to bleed out and harden
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Why do Arab traders rub noses with their suppliers?
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show of respect
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Following the crusades, did the flow of Old World spices increase or decrease
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Trade increased until the rise of the Turkish empire in 1400s
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Three major origins of herbs, spices, and medicinal plants
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* Europe/Mediterranean – Horse raddish, mustard, onions
* Old World Tropic – Black pepper, nutmeg, ginger, cloves, cinnamon * New World Tropic – Vanilla, capsicum peppers, paprika |
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Characteristics that made old world spices good for long distance trade
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long life (dried), chemically potent (you don’t need a lot to make it useful), light (cause its dried).
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Why have old world spices declined so much in value?
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New centers of production, large scale agriculture, synthesis of oils, improved transport
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The difference between cultural prescreen and ethnobotanical filter
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* culture prescreen – the trial and error that occurs over hundreds or thousands of years
* ethnobotanical filter – scans plants present in and gets the ones that are used pharmacologically and submits them for drug development screening |
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Which old world spice is coppiced to produce numerous long straight shoots?
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cinnamon
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Which old world spice produces two spices from the same fruit?
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Nutmeg (Seed) and Mace (Aril)
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Which old world spice is an important ingredient in cigarettes?
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Cloves (they pop when you smoke ‘em… kretek! Bit**!)
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What is the difference between true cinnamon and cassia?
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Cinnamon –uses only inner bark and is powdery ; Cassia- crude and uses entire bark
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What member of the ginger family is responsible for the yellow color or curry?
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Tumeric
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What girl brings Angelo infinite happiness?
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Marjorie
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What part of cardamom is used in spice?
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seeds
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Characteristics of the Ginger Family
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* perennials (don’t die at end of growing season), aromatic, thich rhizomes, alternate leaves, in SE Asia,
* cardamom, turmeric, curcumin |
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Characteristics of the Mint Family
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* Square stems, strong scents, opposite leaves,
* bilateral symmetry, circles are ovaries that contain 4 nutlets * fat soluble but not H2O soluble, volatile (evap at low temp), essential oils stored in special cells, aromatic * Spearmint/peppermint, rosemary, basil, oregano/marjoram, sage, thyme |
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Characteristics of the Parsley Family
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* (vegetative) compound leaf (many leaflets), flowers come from one part of the stem (umble –inverted umbrella), aromatic
* (reproductive) radial symmetry, flower has 2 ovules and splits down center * Dill, coriander, cilantro, parsley, cumin, chervils |
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Characteristics of the Mustard Family
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* Four petals (like a cross- cruciferae), Fruits open on 2 sides; silique, contains a sulfur compound
* Horse radish, wasabi, mustard |
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Parsley family members that are used for both leaves and seeds
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Dill (seeds and leaves)
and cilantro (leaves) coriander (seeds) |
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5 commonly used herbs in the Mint family
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spearmint/peppermint, rosemary, basil, oregano, sage
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Aztecs used ( ) to flavor chocolate
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Vanilla
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A spice the combines the flavors of cinnamon, cloves, and nutmeg in one fruit is
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Allspice
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The compound in chili peppers that creates the burning sensation is
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capsicum
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Of the three New World Spices, the one that made the greatest contribution to the regional cuisines in Europe and Asia is
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nutmeg
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Peyote is the source of the hallucinogenic drug
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mescaline
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What is the average cost of bringing a new pharmaceutical drug to market, from initial discovery to obtaining FDA approval?
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800millon to 1.7billion
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How long does a patent last?
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20 years
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Why should you avoid henbane in salads?
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It’s a poisonous hallucinogen
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Horseradish is obtained from what part of the horseradish plant?
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Root
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What family of plants does wasabi belong to?
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Mustard
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What plant in the parsley family has licorice scented seeds?
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Chervil
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What culinary herb is an important ingredient in pesto?
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Basil
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How have concerns over intellectual and genetic property rights affected bioprospecting?
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each signatory nation has sovereignty over all biodiversity within its boundaries (genetic) and communities should be compensated for the knowledge acquired through generations of cultural pre-screening (intellectual)
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bioprospecting
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search for new pharmaceutical or industrial chemicals from plants and animals
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biopiracy
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bioprospecting activities that do not adequately address issues of intellectual and genetic property rights
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prior informed consent
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local communities, in addition to national, must also give consent for research activities
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Three ways in which plants package secondary compounds
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* Externally (like mints and the hairs that contains oils in balloon like things)
* Internally (like in bay leaves) * Seperately (like in onions or mustard seeds) glycocinalates + enzymes = isothiocyanates |
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Compounds responsible for heat in mustard seeds and chili peppers?
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glycocinalates + enzymes = isothiocyanates and capsaicin
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Why do mustard seeds have to be crushed to get the heat?
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The compounds that create the heat are combined in seed and have to be crush to be mixed
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Different reactions of birds vs mammals to hotness of capsicum peppers?
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Most mammals don’t like capsaicin (the compound that makes peppers hot). Birds are attracted by the color and disperse the pepper seeds.
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Mistletoe is being tested by the NCCAM as a potential treatment for what disease?
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Cancer (chemotherapy)
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What does NCCAM stand for?
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Nation Center for Complementary and Alternative Medicine
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What religious sect considered mistletoe sacred because it grew on trees?
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Druids
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How do alkaloid names usually end?
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–ine
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What plant secondary compound consists of sugar bonded to non sugar compound ?
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glycosides
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Difference between naturally occurring salicin and aspirin?
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Aspirin has an acetyl acid attached to it which removes some of the negative side effects (stomach pain and nausea)
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How does taxol interfere with growth of cancer cells?
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Interferes with microtubules during cell division
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Medicinal plant whose root resembles a human body?
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Mandrake
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Hallucinogenic compound responsible for nutmeg psychosis?
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Myristicum
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A spice from the orchid family
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Vanilla
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Hallucinogenic plant in the Cactus family
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Peyote
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Characteristic of Lambs ear that make it an herbal bandaid
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soft furry texture
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What is an example of culinary herbs that sometimes spread to aggressively in gardens?
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Catmint, spearmint, and peppermint
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