Hormones And Diseases

Front 1

Prolactinomas

Back 1

Hyperpituitarism

Front 2

Graves Disease

Back 2

Hyperthyroidism - Autoimmune disease where antibodies stimulate TSH receptors to produce T3 + T4 in excess. (results: Low T3 and High TSH).
Swollen legs, bulging eyes, hair loss, diarrhoea

Front 3

Hashimotos Thyroiditis

Back 3

Hypothyroidism - destructive autoimmune disease. Thyroid gland infiltrated by lymphocytes enlarging thyroid (goitre).
Thyroid destroyed.
Constipation, bradycardia, amenorrhoea

Front 4

Conn's Syndrome

Back 4

Hyperaldosteronism - adenoma of zona glomerulosa. Increased sodium + water retention (Increased blood pressure). Secondary hypertension.

Front 5

Cushings Syndrome

Back 5

Excess Cortisol. From disorder in Ant. Pituitary or Adrenal Cortex. Excess production of glucocorticosteriods.
Obesity, hypertension, ankle oedema, glucose intolerance, peptic ulceration.

Front 6

Addisons Disease

Back 6

Insufficiency of Adrenal Cortex.
Deficient secretion of mineral and glucocorticoids.
From progressive destruction of adrenal cortex (either tumour, autoimmune or infection)
Postural Hypotension, Weight loss, Constipation

Front 7

Phaeochromocytomas

Back 7

Increased stimulation of Adrenal Medulla.
Excess NE/E produced by catecholamine-producing cells in adrenal medulla.
Hypertension, headaches, can lead to heart failure.
Test for free metanephrines.

Front 8

Edwards Syndrome

Back 8

Trisomy on chromosome 18

Front 9

Downs Syndrome

Back 9

Trisomy on chromosome 21

Front 10

Pataus Syndrome

Back 10

Trisomy on chromosome 13