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15 Cards in this Set
- Front
- Back
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What does STAR do? |
steroid acute regulatory protein transports cholesterol into mitochondria acth dependant rate limiting |
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What are the enzymes involved in aldosterone synthesis? |
3 beta hydroxysteroid dehydrogenase 45 isomerase 18 hydroxylase 18 dehydroxydehydrogenase |
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What are the enzymes involved in glucocorticoid synthesis? |
17 alpha hydroxylase p450c17 protein |
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What enzymes are involved in androgen synthesis |
17,20 lyase, or 17,20 desmolase -- part of p450c17 |
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How do aldosterone and cortisol get around in the blood? |
bound to cortisol binding protein and trasncortin |
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What is the rate limiting step in testosterone synthesis? |
STAR |
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What is the enzyme involved in testosterone synthesis? |
17 beta hydroxysteroid dehydrogenase |
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What is the more potent form of testosterone? |
Dihydroxide testosterone formed in peripheral tissues by 5 alpha reductase |
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What do the sertoli cells produce? |
androgen binding protein inhibin |
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What is the main form of estrogen? |
17 beta estradiol |
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What does placental lactogen do? |
acts like prolactin and GH |
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What prostaglandin is synthesized via the lipooxygenase pathway? |
leukotrienes |
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What prostaglandin is synthesized via the cyclooxygenase pathway? |
Prostaglandins prostacyclin pg12 thromboxane TXA2 |
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What does PDGF do? |
Platelet derived growth factor stimulates growth of mesenchymal and glial cells |
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Why isn't HRT used? |
it has deadlier side effects such as MI, cancer, breast cancer |
