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17 Cards in this Set

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  • Back
What is diabetes?
A condition in which the amount of glucose in the blood is too high because the cannot use it properly
What is the only hormone that can lower blood glucose?
Insulin
What dose insulin do?
Transports glucose in to cells such as muscle ,fat and liver cells beacuse its presence causes an increase in the number of glucose transporters ,It also increases the activity of cells which store glucose and glycogen
What happens the insulin concentration after a meal?
It increases
What organ secretes insulin?
Pancreas
Where in the pancreas is insulin and glucagon made?
The endocrine part of the pancreas
What is the difference between glucagon and insulin?
GLucagon raises blood glucose levels insulin lowers it
what enzymes can raise blood glucose?(4)
a) Glucagon
b) Cortisol
c)Epinephrine
d) Growth hormone
How dose the kidney handle glucose?
It filters it into tubules and then reabsorbs it 100% unless there is too much for it too handle and some is lost in urine
Why do people with diabetes piss more?
Glucose in the urine will suck more water into the urine (osmosis) and cause excess urine production
Why cant glucose cross cell membranes by simple diffusion?
It's water soluble
What is the name of the glucose transporter molecule that insulin increases the ammount of?
GLUT4
What is GLUT3?
This is the glucose transport molecule in the brain which allows the brain to still take glucose in the absence of insulin
When there is no glucose what alternate source of energy is used?
Fat metabolism
Can the brain take advantage too the free-fatty acids produced by fat metabolism
NO
What is the side effect of excess lipid metabolism ?
there is a build up of ketoacids in the blood this results in a oder in the breath similar to that of acetone
Why might diabetics have poor circulation?
Excess sugar makes the blood syrupy (more viscous : harder for the heart to pump.Also the excessive urine production dehydrates the body and reduced blood volume