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13 Cards in this Set
- Front
- Back
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Penacillianase resistant pens |
Methacilian, Nafcillian, oxacillian
disruption of peptidoglycan pen works on gram + |
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First generation cephalosporins |
cefazolin (Ancef), cephaparin, cephalexin,
Gram + cocci (uncomplicated skin)
Disrupts cell wall synthesis
Transaminitis/nausea/diarrhea/rash
Oral contraceptives and coumadin |
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Second generation cephalosporins |
Cephacor, cefotetan, Cefoxitin, cefprozil, cefuroxime
Gram + and Gram -
Disrupts cell wall synthesis Transaminitis/nausea/diarrhea/rashEtOH = bad
Oral contraceptives and coumadin |
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Third generation Cephalosporins
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Ceftriaxone, cefpodoxime, cefdinir, cefixime, Ceftazadim (Pseudomonas)
Hemof influ, Gram - does not work as well for gram +
Disrupts cell wall synthesis Transaminitis/nausea/diarrhea/rash EtOH =bad
Oral contraceptives and coumadin |
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Fourth generation cephalosporins |
Cefepime
Gram + cocci, gram - bacilli, ESBL, Betalactamase producing strains |
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Fifth generation Cephalosporine |
Ceftaroline
MRSA coverage, and e facealis |
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Fluoroquinolones |
Cipro, levo, moxi, norflo
Inhibit DNA replication
UTI, PNA, prostatits,
Blood glucose disturbances arrhythmias, tendon ruptures (especially in those taking corticosteroids), neuropathy, and CNS nervousness, agitation, insomnia, anxiety, nightmares, |
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Aminoglycocides
Orally or parenterally |
Gentamycin, tobramycin, neomycin, kanamycin, Amikicin,
Aerobic, gram - and some gram + common for abdominal and UTI
!!Nephrotoxicity!! |
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Monobactams (Parentaral) |
Aztreonam
B lactam ring, only work against gram - bacteria |
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Carbapenums (Parenteral) |
Ertapenum, Imienum, Meropenum
Extremely broad spectrum, No MRSA |
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Marcolides |
Azithromycin, clithromycin, dirthromycin, erythromycin, clindamycin
Gram + and -
Inhibit protein synthesis P 450 inhibitor
N/VD QT ototoxicity Digoxin theophyline |
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Glycopeptides |
Vancomycin |
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Sulfonamides
cotrimoxazole |
Inhibit folate production. Need immune system to kill remaining |
