Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
18 Cards in this Set
- Front
- Back
|
What is the age distribution of Hodgkin lymphoma? |
1. Bimodal 2. Affects young and old |
|
|
What virus can lead to Hodgkin lymphoma? |
1. EBV |
|
|
What are the epidemiological factors leading to Hodgkin lymphoma? |
1. High standard of living 2. Immunosuppresion 3. Autoimmune disorders |
|
|
What is the MC Hodgkin lymphoma? |
1. Nodular sclerosis |
|
|
1. R-S cells |
|
|
What type of bx is best for morphology? |
1. Excisional bx |
|
|
1. Nodular sclerosing |
|
|
What is the presentation of Hodgkin lymphoma? |
1. Asymptomatic adenopathy 2. Mediastinal mass 3. Night sweats 4. B ssx 5. Itching |
|
|
What ssx of Hodgkin lymphoma can get worse with drinking? |
1. Painful lymph node |
|
|
What imaging is best for Hodgkin? |
1. PET scan** 2. CT of chest, abdomen, and pelvis--- surveillance |
|
|
When is the use of radiation in Hodgkins lymphoma used? |
1. Early stages-- IA and IIA 2. Asymptomatic patients 3. Tx to cure |
|
|
What is the use of chemo in Hodgkins lymphoma? |
1. Tx to cure 2. Combo chemo |
|
|
What are the chemo regimens? |
1. MOPP 2. ABVD |
|
|
What are the cure rates in Hodgkin lymphoma? |
1. 60-85% 2. Best in IA and IIA 3. Worst in stage IV |
|
|
What are the side effects of radiation? |
1. Hypothyroidism 2. Radiation pneumonitis 3. Constrictive pericarditis 4. Accelerated atherosclerosis
|
|
|
What secondary malignancies can occur due to radiation? |
1. Breast cancer 2. Lung cancer 3. Stomach cancer |
|
|
What are the side effects of chemo? |
1. Sterility 2. Cardiopulmonary issues |
|
|
What secondary malignancies can be caused by chemo? |
1. AML 2. Non-Hodgkin lymphoma 3. Myelodysplastic syndromes |
