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53 Cards in this Set

  • Front
  • Back

Blood flow in the heart

Inferior/superior vena cava into right atrium


right ventricle through tricuspid valve


pulmonary artery through pulmonic valve to lung


pulmonary vein to left atrium


left ventricle through mitral valve


aorta through aortic valve to body


Electrical impulses in heart

SA node


into atria through bachmans bundle


internodal tracts to AV node


delay at AV node


Bundle of His splits, activates ventricles


purkinje fibers cause contraction


ventricles repolarized

ECG components

P- SA node/conduction through atria


PR - delay at AV node


QRS ventricular contraction


ST - repolarization

LDL and atherosclerosis

transports fat and cholesterol to tissues

Platelets and atherosclerosis

secrete growth factors- encourage scar tissue formation.


smooth muscle cells divide and decrease artery width

Monocytes and atherosclerosis

Uptake lipids, results in foam cells

How do antioxidants prevent atherosclerosis

Reduce the oxidation of LDL

Saturated Fats

Increase cholesterol


potential source of damage to blood vessels

Tachycardia

Rapid heart rate >100 BPM


stress, drugs, other conditions

Bradycardia

Slow heart rate <60 BPM


fainting occurs at 30

PVC - Premature ventricular contraction

extra beat of ventricle


incomplete filling of ventricles


irritable tissue causes extra stimulus

PAC - premature atrial contraction

extra beat in atria


incomplete fillling of atria

Similarities between PAC and PVC

Feels like a beat skipped


reduction in ejection fraction

Heart Block

electrical signal is slowed or disrupted


usually due to damaged tissue

Asystole

No electrical activity


flatline on ECG


due to damaged tissue

Ventricular fibrilliation

Random electrical signals - uncoordinated contraction


defibrillation

Does the AV node slow or speed heart rate

SLOW

Myocardial Infarction on ECG

ST segment elevation

Heart muscle ischemia

ST segment depression

Septal Defect

mix of oxy/deoxygenated blood in ventricle


blue skin

patent ductus arteriosis

aorta connected to pulmonary artery


hole between atria


lungs inflate - process de/oxygenated blood


requires surgery

Rheumatic Heart Disease

Pain in joints


develops in response to strep infection


fibrosis of heart, specifically mitral valve

mitral valve prolapse

mitral regurgitation - from ventricle to atrium

Tetralogy of Fallot

Ventricular septal defect


aorta pushed to side


pressure on pulmonary valve from aorta


right ventricular hypertrophy

Insulin

Regulates metabolism of carbs and fats


Produce by beta cells in pancreas


promotes absorption of glucose into skeletal muscle


causes fat to be stored


defficiency results in high blood glucose

diabetic coma

eat, no insulin

insulin shock

insulin, no eat

Serum Coronary Profile - LDL

130mg/dL - lower is better

Serum Coronary Profile - HDL

40-60mg/dL - higher is better

Serum Coronary Profile - Total cholesterol

180 mg/dL, <200 - lower is better

Serum Coronary Profile - Triglycerides

10-150 mg/dL - lower is better

Serum Coronary Profile - Glucose

100 mg/dL

Most common cancer

skin cancer

most common in males

prostate, lung, colorectal

most common in women

breast, lung, colorectal

Most rapid and dangerous cancer

malignant melanoma

Anaplasia

less adult function in cell, resembles fetal cells

hyperplasia

higher cell division

differentiation

ability of cells to perform functions of well differentiated cells, resemblance of cancer cells to environment

encapsulation

hyperplastic cells with capsule show no metastasis, indication of benign mass

cancers that cause most deaths

lung, colorectal, breast, prostate

oncogenes

cancer genes - cause poorly differentiated cells to divide and cause cancer

proto-oncogenes

required for production of normal cells, damaged by carcinogens, send messages to fetal cells

initiation

carcinogens cause mutations in a gene

promotion

damaged cells divide

anti-promotion

discourages damaged cell division

Why are multiple mutations needed

needs an initiator, promoter, and initiator must mutate several parts of a gene

isoflavones, phenols, carotenoids

fruits and vegetables

carcinoma

epithelial tissue - organs

sarcomas

connective tissue, bone, muscle, fat

lymphoma

blood

leukemia

blood

Smoking and carcinogens

radioactive components, carbon monoxide, nicotine poisoning