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29 Cards in this Set

  • Front
  • Back

Surveillance

keeping track usually over time or at a specific time of the occurrence of morbidity, mortality, and injury/disability

The purpose of surveillance

detect changes in disease trends and to initiate appropriate prevention and control/protection measures

Surveillance is....

systematic ongoing collection, collation, analyses of data, and the timely dissemination of info for those who need to know so that action can be taken

Screening

presumptive identification of an unrecognized disease or defect by the application of tests, examinations, or other procedures which can be applied rapidly to sort out apparently ill/well persons, who probably have a disease, from those who probably do not

Presumptive

a belief supported by probability

T/F a screening test is a diagnosis

false; it is not a diagnosis


Screening level

the normal limit or cutoff point where a screening test is considered positive

Screening tests are designed to be...

applied to large groups of people, innocuous or non-intrusive, safe, inexpensive, acceptable to the people being screened, reliable, valid

Criteria for Disease Selection when to screen

condition should be an important health issue,


an investigator should be able to differentiate diseased individuals from non-diseased individuals through diagnostic tests,


prognosis should be improved if the disease is detected and treated early

Sensitivity

Se


the proportion of truly diseased persons based on true status in the screened populations who are identified as diseased by the screening test

Sensitivity measures the probability of...

correctly identifying a case with the disease

Specificity

Sp


the proportion of truly non-diagnosed persons based on true status who are correctly identified by the screening test

Specificity measures the probability of...

correctly identifying a non-diseased person

Positive Predictive Value (PPV)

the probability that a positive test is positive when all positive tests are taken into account; meaning both true and false positives are taken into account

Negative Predictive Value (NPV)

the probability that a negative test is negative when all negative tests are taken into account; meaning both true negatives and false negatives

SE=

a/a+c x 100%


Sp=

d/d+b x 100%

PPV=

a/a+b x 100%

NPV=

d/d+c x 100%

Validity =

Se + Sp - 100%

What are 2 measures of validity?

Sensitivity and Specificity

What are the 2 most important measures of a screening test?

Se and Sp

Yield

the % of TPs accurately identified by a screening test

Yield =

TP/Total x 100%

Accuracy =

(TP + TN/Total Sample) x 100%

Variation/bias is a function of the following`

# of observations, # of observers, # of patients, the administrators knowledge of the test

What happens when you increase prevalence and observe the affects on PPV and FP?

Prevalence and PPV increase


FP decreases

What happens when you increase specificity and observe the affects on PPV and FP?

SP and PPV increase


FP decrease


What are two ways to reduce FPs?

Prevalence and SP increase