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35 Cards in this Set

  • Front
  • Back
What is HIV
HIV is the retrovirus that hs the latent infection that stays in the CNS while the bondy can fight off the infection
What is AIDS
is the disease whent he body can no longer fight off the HIV virus. The CD4 are less than 200 and the viral load is 55,000 copies/ml and there are clinical s/s
Stages of HIV infection
Primary - acute
Chronic Asymptomatic
Severe Immune Compromise
Candidiasis Yeast
Oral Thrush
NI Nystatin swish and swallow and lidocaine oral to numb mouth
HPV and HIV cervical cysplasia
HPV is genital wart and HPV is human papillomavirus associated with cervical dysplasia
PAP tests every 4-6 months and early treatment for cancer
Kaposi Sarcoma
Cancer of endothelial layer of blood and lymph vessels (red adn blue blotches and lesions may bleed)
Treat with vincristine and bleomycin and treat aids
PCP
opportunistic neumonia seen in clients with AIDS. Treat aids and agive TMP-SMZ (Bactrim)
Wasing Syndrome
Sign of last stages of AIDS. A protein-energy malnutrition and diarrhea for greater than 30 days resulting in loss of 10% of more of body weight.
BRAT diet, high protein supplements, and drugs to treat AIDS
What are measure that the nurse can take to help decrease the risk of the AIDS client from getting an infection
immunizations, instruct to avoid crowds, wear a mask aroud others, and nurse should avoid caring for client when she has a fever or respiratory infection.
NI - Preventindg the spread of HIV/AIDS - First level
Educate public about HIV/AIDS and prevention and educate HCP how to decrease exposure through standard precautions
NI - Preventing the spread of HIV/AIDS - second level
Early identification of HIV/AIDS and early treatment
NI - preventing the spread of HIV/AIDS - Tertiary level
immunize client (pheumonia, flu, hepatitis, etc), early detection of opportunistic infections, and treatment and early recognition of antiretroviral theirapy regime failure.
What measures should the health care professional take to protect themselves from HIV/AIDS?
Standard precautions, never recap a needle
What should the HCP do if coming in contact with blood?
Wash area with sop and water, tell supervisor, prompt medical care
What is PIP and what follow-up should the HCP excpect
Post exposure prophylaxis (PEP) within 2 hours and need Retrovir (AZT) x 4 weeks, and HIV testing post-exposure; 6 weeks; 3 months; 6 months; 1 year. If positive for HIV at any time - test CD4 cells and viral load and treat if has AIDS.
Nucleoside reverse transcriptase Inhibitors (NRTI)
Virus uses the NRTI instead of the normal building block, then reproduction of the virus is stalled
Non-nucleoside reverse transcriptase inhibitors (NNRTI)
Bind and disable reverse transcriptase, a protein that HIV needs to make more copies of itself.
Protease Inhibitors (PI)
Disables protease, a protein that HIV needs to make more copies of itself.
Fusion Inhibitors (FI)
work by blocking HIV entry into cells.
Wht is Retrovir the most frequently prescribed drug for AIDS
Nucleoside Reverse Transcriptase Inhibitor (NRIT)
Instructions for Retrovir
Take tables on empty stomach, swallow whole and drink plenty of fluid.
Take capsules with or without food.
Caution- Bactrim may increase risk for neutropenia
Side Effects of Retrovir
GI intolerance
bluish brown bands on fingernails
dilliculty swallowing
numbness
tingling and pain in lower extremities
mental changes
pruritis
Treatment regime consideration
client compliance
number of meds
interactions with other meds
other diseases and conditions present
pregnancy
Key to help client adhere to regime
client's lifestyle, instruct how drugs work, open channel of communication, monitor for adherence.
Successful regime for HAART
test viral load 2-8 weeks after starting treatment and then every 3-4 months. If viral load is still detectable after 4-6 months cause for regime failure needs to be determined
Virologic failure
Viral load does not become undetectable and if treatment regime is not changed will progress to immunologic failure in 3 years.
Immunologic failure
regime ineffective to raise CD4 cells or prevent count from decreasing
Clinical failure
HIV related illness despite 3 months of drugs
Standard of practice for pregnant woman with AIDS/HIV and her child to receive
ZDV regime week 14 to 34
ZDV given IV during L&D
Baby takes ZDV liquid form every 6 hours for six weeks
Primary Stage of HIV
Flu-like symptoms in 50-9-% of newly infected persons the first month after exposure.
Chronic Asymptomatic HIV infection stage
after 3-6 months, immune system stabilizes adn HIV is established in the CNS, lymph nodes, and mononuclear cells
Sever Immune Compromise
Advanced HIV disease or late-stage infection. CD4 and lymphocytes fall, the person is susceptable to opportunistic infections and pathogens and can succumb to an infection because of not having a strong enough immune system to fight the illness and the client will die.
Populations at risk
injetion drug users
homosexual sex
unprotected intercourse -esp adolescents
HIV contaminated blood products
prenatal transmission
sparp-related injuries
Riace if a factor
Caucasian 38%
Hispanic 20%
African American 40%
DX of HIV
ELISHA (enzyme-linked immunoabsorbent assay)
Western Blot performed on all positive ELISHA
Rapid IV test (results back in 5 - 30 minutes)
DX of AIDS
CD4 count less than 200 cells/mm3
Viral Load Test (55,000 copies/ml)
AIDS defining condition