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15 Cards in this Set
- Front
- Back
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MOA of fusion inhibitors
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Interfere with the virus' ability to fuse with and enter the host cell
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Mariviroc
1.) Brand 2.) MOA |
1.) Selzentry
2.) The drug blocks the CCR5 receptor located on some immune cells ONLY. |
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MOA of NNRTIs
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Bind directly onto reverse transcriptase preventing the conversion of RNA into DNA
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MOA of NRTIs
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Incorporates into the viral DNA preventing the bulding process of DNA
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Class ADR of NRTIs
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Lactic Acidosis
Heptaomegaly Peripheral Neuropathy Pancreatitis |
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Class ADRs of PIs
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DM
Central Obesity Lipodistrophy Increase in TG, Chol, NOT HDL |
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Class ADRs of NNRTIs
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Rash
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Preferred PI-based regimen
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Lopinavir/Ritonavir (Kaletra) + Lamivudine + (Zidovudine + Stavudine)
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Preferred NNRTI-based regimen
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Efavirenz + Lamivudine + (Zidovudine or Tenofovir or Stavudine)
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Raltegravir
1. Brand |
Isentress
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Which HIV drugs can be taken with food?
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Saquinavir
Kaletra Ritonavir Nelfinavir |
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Which HIV drugs can't be taken with alcohol? (Disulfiram reaction)
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Norvir
Kaletra Abacavir |
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Which HIV medication has a black box warning of causing bleeding to the brain? (give brand and generic)
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Timpranavir (Aptivus)
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Which HIV medications need refrigeration?
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Norvir
Kaletra |
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Which HIV medications need to be taken on an empty stomach?
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Didanosine
Indinavir (Crixivan) |
