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56 Cards in this Set

  • Front
  • Back
CCR5 anatagonist
maraviroc...must be a macrophage x5 virus...must see if patient is trophic
raltegravir
integrase inhibitor which has side effect of unfavorable lipid profile
GI interance and p450 inhibitors therefore increases blood levels of other drugs
protease inhiibitor
lipodystophy and hyperglycemia
saqinavir indinovir and amprenovir
pancreatits as a protease inhibitor
ritonavir
nephrolithiasis...HIV patient with kidney stones is taking...
indivavir
NRTI what cause pacreatits and peripheral neuropathy
didavudine, zalcitabine, stauvudine
NRTI that cause hepatic steatosis
didavudine and stauvudine
NRTI causing hypersensitivity reactions is
abacavir
bone marrow suppressing fixed by GM-CSF and megaloblastic anemia
zidovudine
class effect is rash
NNRTI... no need to activate in cell
false positive test for cannibinoids
efavirenz
confusion
efavirenz
Nevir, ef with dec
NNRTI
inhibit fusuion and entry into CD4 cell by blocking (env)gp41
enFUvirtide...FU=fusion
causes hypersensitivaty at injection site and increases risk for pneumonia
enfuvirtide
lactic acidosis
NRTI except abacavir (AZT, didanosine, zalcitabine, stauvudine, lamivudine)
GI intolenace
navir
pancreatitis
ritonavir, didanosine, zalcitabine, stauvudine
peripheral neuropathy
didanosine, zalciabine, stauvudine
megaloblastic anemia
zidovudine
rash
NNRTI
hyperglycemia, diabetes, lipid abnormalities
saquinavir, indinovir, amprenavir
bone marrow suppression
zidovudine
occupational exposure
zidovudine and lamivudine
ADD
modafinil
atypical antipsych that cause diabetes and weight gain
olanzapine, clozapine, quitapine
dopamine antagonists in the brain do what do cAMP levels
increase cAMP because D2 is a Gi receptor
gene mutated in those who get malignant hyperthermia
RYR1 gene
progression on typical neuroleptic EPS side effects...what happens after hours
dystonis
progression on typical neuroleptic EPS side effects....what happens after days
PD like symptoms
progression on typical neuroleptic EPS side effects...what happens after weeks
spasticity and restlessness (akinesia
progression on typical neuroleptic EPS side effects...whatt happens after months
tarditive dyskinesia... irrvesible looking at the mouth
treatment for bipolar
lithium, valproic acid, carbamazopine, lamotrigine
contraindicated in pt with bipolar
SSRI
drugs that increase the blood levels of lithium
ACEi, NSAIDS, diuretics (either decrease water or decrease GFR
lithium side effects (kidney excreted)
DI, hypothyroid, muscle excitability and agitiation, tremor, heartblock
post partum time separation
2 weeks, past two weeks, psycholsis
drugs that decrease the seizure threshold
BII...buproprim, imipenum, INH
TCA unique uses...imipramine? clomipramine, nortryptyline, desipramine?
imipramine=bed wet, clomipramine=OCD, nortryptline= less anti cholinergic, desipramine=least sedating
TCA tox and treatment
CCC...spasm to hyperpyrexia...give naHCO2
fluoxatine
long acting SSRI
cita, sertparotxitine, fluoxitine
SSRi
social phobia
SSRI
when SSRI taken with MAOi, SNRI, sibutramine....what do u give
this is serotonin syndrome...cool them down then give cyproheptidine a (serotonin antagonist)
nefazodone, milnacipran, sibutramine
SNRI...sibutramine is used for weight loss
dulo adverse effect
diabetic periph neuropathy
phenelzine, tranylcypromine, isocarboxazid, selegine and capsone
MAOi used for atypical depression and hypochondriasis
MAOi worse case is malignant hypertension
with wine and cheese (tyrosine not broken down by MAO in cut)...beta-agonists...must give 2 weeks wash out period
A/E of TCA (amytriptyline)
inhibit reuptake of NE and serotonin, anti alpha effects cause hypotension, block fast Na channels causing conduction defects, block muscarinic recpetors causing delirum hot flush, block histamine causing sedation
alpha 2 blocker and 5-HT2 and 3 antagonist tox... (mert wont stop eating or sleeping)
mirtazapine causes sedation increased appetite therefore use in depressed with sleeping problems or depressed with eating problems
Trazodone and Maprotiline
inhibit serotnin and NE reuptake respectivly...trazadone used for insomnia too
atypical neuroleptic that causes prolonged QT
ziprasidone
make sure you check LFT on
INH and carbamazipine
thyroid tox
lithium and amioderone
clozipine
seizures and aplastic crisis