Hiv Drugs

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Nevirapine
Indications:

Back 1

Treatment of HIV-1 infected patients who have experienced clinical or immunologic deterioration, in combination with other antiretrovirals

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Nevirapine
Actions:

Back 2

Binds to HIV-1 reverse transcriptase and blocks replication of the HIV by changing the structure of the HIV enzyme

Front 3

Nevirapine
Adverse effects:

Back 3

Headache
nausea
vomiting
diarrhea
rash
liver dysfunction
chills
fever

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Zidovudine
Indications:

Back 4

Management of adults with symptomatic HIV infection in combination with other antiretrovirals
prevention of maternal–fetal HIV transmission

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Zidovudine
Actions:

Back 5

A thymidine analogue that is activated to a triphosphate form, which inhibits the replication of various retroviruses, including HIV

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Zidovudine
Adverse effects:

Back 6

Headache
insomnia
dizziness
nausea
diarrhea
fever
rash
bone marrow suppression

Front 7

Fluconazole
Indications:

Back 7

Treatment of oropharyngeal, esophageal, and vaginal candidiasis; cryptococcal meningitis; systemic fungal infections; prophylaxis to decrease incidence of candidiasis in bone marrow transplants

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Fluconazole
Actions:

Back 8

Binds to sterols in the fungal cell membrane, changing membrane permeability; fungicidal or fungistatic depending on concentration of drug and organism

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Fluconazole
Adverse effects:

Back 9

Headache, nausea, vomiting, diarrhea, abdominal pain, rash

Front 10

Antiretroviral- Assesment
Implementation

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1. Renal Dysfunction
2. Severe CNS disorders that could be aggravated by these medications
3. Pregnancy and lactation
1. Encourage Hydration
2. Support drug compliance
3. Protect pt from injury if CNS side effects occur
4. Monitor renal function tests

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Nursing Considerations for Patients Receiving Agents for HIV and AIDS
1. Assesment

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a. Renal or hepatic dysfunction
b. pregnancy or lactation
c. CNS effectso f drugs
d. Skin monitor for effectiveness
e. Check temperature to monitor for infections

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Abacavir (ABC)- adverse effects
Nucleoside Reverse Transcriptase Inhibitors (NRTIs

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Hypersensitivity reaction which can be fatal; symptoms may include fever, rash, nausea, vomiting, malaise or fatigue, loss of appetite, respiratory symptoms such as sore throat, cough, shortness of breath

Front 13

Didanosine
avderse effects
Nucleoside Reverse Transcriptase Inhibitors (NRTIs

Back 13

Pancreatitis; peripheral neuropathy; nausea; diarrhea. Lactic acidosis with fatty degeneration of the liver (rare but potentially life-threatening toxicity associated with use of NRTIs).

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Emtricitabine
Nucleoside Reverse Transcriptase Inhibitors (NRTIs

Back 14

Minimal toxicity; lactic acidosis with hepatic steatosis (rare but potentially life-threatening toxicity with use of NRTIs).