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50 Cards in this Set

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Where are the cell bodies for the ANS and processes for the ANS>
Cell bodies- in the CNS

Processes - PNS
What does ectoderm give rise to?
suface ectoderm, neural tube, and neural crest
What does the neural crest cells create?
components of the PNS - Schwann cells, sympathetic and parasympathetic systems, suprarenal medualla, melanocytes, odontoblasts, neuroglial cells
What are the supporting cells called in the CNS and PNS?
CNS = neuroglia

PNS - Schwann and satellite cells
What is the gray matter?
neuron cell bodies and neuroglia
What is in the white matter?
neuronal processes and neuroglia
What is in a ganglia?
neuron cell bodies, Schwann, and satellite cells
Where is the only place you find a nerve cell body in the PNS?
in the ganglia
What are nissl bodies?
stacks of rER - function is to produce neurotransmitter substance
Where in the cell lacks nissl substance? Why?
The axon hillock -- no nissl bodies because cytoskeletal elements take up all the space
How do axons branch? what are they called?
usually at 90 degree angles -- the branches are called collaterals
What does the axon nerve contain?
ribosomes
Are dentrites myelinated?
Rarely -
What is along the length of the dendrite?
dendritic spines
What does the dendrite contain?
microtubules
What is the cytoskeleton made out of in the dendritic spines?
actin only
Name the types of neurons?
bipolar, multipolar, pseudounipolar
What are each of the types of neruons used for?
Bipolar - special sense
Multipolar- motor
Pseudounipolar - sensory and dorsal root ganglia
Why is the post synaptic face easier to identify?
because of the thickening of the cell membrane
What is the presynaptic face full of?
synaptic vesicles
What are the type of synapses/
1. Axosomatic
2. Axoaxonic
3. Axodendredic
4, Axospinous - an axon endding on a den dritic spine
Which synapse is most common?
axodendritic synapse
What is the dendritic shaft full of?
microtubules and a little actin
Where is the Schwann cell cytoplasm?
predominantly located along the outer aspect of the myelin sheath
What are the external and internal mesoaxon?
Internal - The original site of invagination

External - the external gap where the 2 myelin's meet
What is the portion of the neuronal process wrapped by a single Schwann cell?
an internode
What are the Nodes of Ranvier?
The naked gaps between myelinated segments
What are Cytoplasmic clefts that appear within the myelin sheath?
clefts (incisures) of Schmidt-Lanterman
What does a schwann cell myelinate?
one segment of 1 neuronal process
What is the major dense line?
where the 2 inner leaflets are close (has a little cytoplasm inbetween)
What is the intraperiod line?
the two outer leaflets meet - extracellular space in between
What can an oligodendrocyte mylinate?
more that 1 process -- each process off the cell myelinated 1 internode of the axon
What is a difference between the myelin from a Schwann cell and an oligodendrocytes?
Schwann -- uses Myelin Protein Zero

Oligodendrocyte-- uses Proteolipid Protein
What are Myelin Protein Zero adn Proteolipid protein used for?
Glue -- attaches the myelin to its plasma membrane. Stabilizes the several layers of myelin
What is the conduction called where it jumps from node to node?
Saltatory conduction
What type of axons, myleinated or not, is more effecientally metabolically?
Myelinated - dont have have to have Na pumps all along the axon - just at the internodes
Where is the cytoplasm in a schwann cell?
1. adjacent to the axon (inner colar
2. between the lamellae( clefts of Schmidt Lantermann
3. paranodal areas
4. outer collar
What is the purpose of the incisures of Schmidt Lanterman?
to keep the inner and outer collar connected with cytoplasm
What are unmyelinated axons surrounded by in the PNS?
A schwann cell and a basal lamina surrounding the Schwann cell
Where can you find mesaxons?
In both mylinated and unmylinated axons
When does unmyelination happen?
When the axon doesnt have the code for myelination
What are the two possibilities for the fate of a Schwann cell?
1. Can only surround 1 cell and myelinate it

2. Can support several unmylinated axons
What is the fuzzy layer that surrounds each schwann cell called?
the endoneurium
What are the layers that cover a nerve?
1. epineurium- outer covering, surrounds the entire nerve- contains blood vessels, ect
2. perineurium - ct that wraps groups of nerve fibers into bundles (fascicles)
3. endoneurium - wraps around individual neuronal processes
What is the endoneurium secreted by?
by fibroblasts within the peripheral nerve
What are the 3 types of neuroglia cells?
1. Astrocytes
2. Microglia
3. Ependymal Cells
4. Oligodendrocytes
How many neuroglial cells are to each neurons?
5- 10
What does an astrocyte do?
It is a packing cell - packs the space so that everything is held together
What establishes the blood brain barrier?
Perivascular feet
What does the end feet of the astrocytes cover?
cover neurons (dendrites and cell bodies), the inner surface of pia mater, and every blood vessel in CNS