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50 Cards in this Set
- Front
- Back
Where are the cell bodies for the ANS and processes for the ANS>
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Cell bodies- in the CNS
Processes - PNS |
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What does ectoderm give rise to?
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suface ectoderm, neural tube, and neural crest
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What does the neural crest cells create?
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components of the PNS - Schwann cells, sympathetic and parasympathetic systems, suprarenal medualla, melanocytes, odontoblasts, neuroglial cells
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What are the supporting cells called in the CNS and PNS?
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CNS = neuroglia
PNS - Schwann and satellite cells |
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What is the gray matter?
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neuron cell bodies and neuroglia
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What is in the white matter?
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neuronal processes and neuroglia
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What is in a ganglia?
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neuron cell bodies, Schwann, and satellite cells
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Where is the only place you find a nerve cell body in the PNS?
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in the ganglia
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What are nissl bodies?
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stacks of rER - function is to produce neurotransmitter substance
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Where in the cell lacks nissl substance? Why?
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The axon hillock -- no nissl bodies because cytoskeletal elements take up all the space
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How do axons branch? what are they called?
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usually at 90 degree angles -- the branches are called collaterals
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What does the axon nerve contain?
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ribosomes
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Are dentrites myelinated?
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Rarely -
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What is along the length of the dendrite?
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dendritic spines
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What does the dendrite contain?
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microtubules
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What is the cytoskeleton made out of in the dendritic spines?
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actin only
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Name the types of neurons?
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bipolar, multipolar, pseudounipolar
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What are each of the types of neruons used for?
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Bipolar - special sense
Multipolar- motor Pseudounipolar - sensory and dorsal root ganglia |
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Why is the post synaptic face easier to identify?
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because of the thickening of the cell membrane
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What is the presynaptic face full of?
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synaptic vesicles
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What are the type of synapses/
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1. Axosomatic
2. Axoaxonic 3. Axodendredic 4, Axospinous - an axon endding on a den dritic spine |
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Which synapse is most common?
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axodendritic synapse
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What is the dendritic shaft full of?
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microtubules and a little actin
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Where is the Schwann cell cytoplasm?
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predominantly located along the outer aspect of the myelin sheath
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What are the external and internal mesoaxon?
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Internal - The original site of invagination
External - the external gap where the 2 myelin's meet |
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What is the portion of the neuronal process wrapped by a single Schwann cell?
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an internode
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What are the Nodes of Ranvier?
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The naked gaps between myelinated segments
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What are Cytoplasmic clefts that appear within the myelin sheath?
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clefts (incisures) of Schmidt-Lanterman
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What does a schwann cell myelinate?
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one segment of 1 neuronal process
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What is the major dense line?
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where the 2 inner leaflets are close (has a little cytoplasm inbetween)
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What is the intraperiod line?
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the two outer leaflets meet - extracellular space in between
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What can an oligodendrocyte mylinate?
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more that 1 process -- each process off the cell myelinated 1 internode of the axon
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What is a difference between the myelin from a Schwann cell and an oligodendrocytes?
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Schwann -- uses Myelin Protein Zero
Oligodendrocyte-- uses Proteolipid Protein |
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What are Myelin Protein Zero adn Proteolipid protein used for?
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Glue -- attaches the myelin to its plasma membrane. Stabilizes the several layers of myelin
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What is the conduction called where it jumps from node to node?
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Saltatory conduction
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What type of axons, myleinated or not, is more effecientally metabolically?
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Myelinated - dont have have to have Na pumps all along the axon - just at the internodes
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Where is the cytoplasm in a schwann cell?
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1. adjacent to the axon (inner colar
2. between the lamellae( clefts of Schmidt Lantermann 3. paranodal areas 4. outer collar |
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What is the purpose of the incisures of Schmidt Lanterman?
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to keep the inner and outer collar connected with cytoplasm
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What are unmyelinated axons surrounded by in the PNS?
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A schwann cell and a basal lamina surrounding the Schwann cell
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Where can you find mesaxons?
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In both mylinated and unmylinated axons
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When does unmyelination happen?
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When the axon doesnt have the code for myelination
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What are the two possibilities for the fate of a Schwann cell?
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1. Can only surround 1 cell and myelinate it
2. Can support several unmylinated axons |
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What is the fuzzy layer that surrounds each schwann cell called?
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the endoneurium
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What are the layers that cover a nerve?
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1. epineurium- outer covering, surrounds the entire nerve- contains blood vessels, ect
2. perineurium - ct that wraps groups of nerve fibers into bundles (fascicles) 3. endoneurium - wraps around individual neuronal processes |
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What is the endoneurium secreted by?
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by fibroblasts within the peripheral nerve
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What are the 3 types of neuroglia cells?
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1. Astrocytes
2. Microglia 3. Ependymal Cells 4. Oligodendrocytes |
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How many neuroglial cells are to each neurons?
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5- 10
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What does an astrocyte do?
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It is a packing cell - packs the space so that everything is held together
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What establishes the blood brain barrier?
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Perivascular feet
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What does the end feet of the astrocytes cover?
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cover neurons (dendrites and cell bodies), the inner surface of pia mater, and every blood vessel in CNS
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