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22 Cards in this Set
- Front
- Back
What are the three layers of the Adrenal Cortex?
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Zona glomerulosa
Zona fasciculata Zona reticularis |
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What does the zona glomerulosa secrete?
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mineralcorticoids (aldosterone)
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What does the zona fasciculata secrete?
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glucocorticoids (cortisol and corticosterone)
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What does the zona reticularis secrete?
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Androgens
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What factor acts on the aona glomerulosa?
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Angiotensin and corticotropin (ACTH)
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What factor acts on the zona fasciculata and the zona reticularis?
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Corticotropin
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What type of cell exists only in the neurohypophysis?
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Pituicytes
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What hormone stimulates testosterone secretion?
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LH
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What do the Sertoli cells of the testis produce?
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Sertoli cells are stimulated by FSH to secrete androgen-binding protein which binds with testosterone to feedback to the pituitary.
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What are chromaffin cells?
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Chromaffin cells are endocrine cells of the adrenal medulla. They secrete catecholamine hormones.
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What is the embryological origin of the adenohypophysis and neurohypophysis?
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Ectoderm of the roof of the mouth becomes the Pars distalis, pars tuperalis, and median eminence. The floor of the diencephalon becomes the Pars nervosa.
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adenohypophysis
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anterior pituitary
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neurohypopysis
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posterior pituitary (pars nervosa & infundibulum)
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ACTH
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corticotropin
stimulates secretion by adrenal glands |
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FSH stimulates what?
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Estrogen/spermatogenesis
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LH stimulates what?
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Progesterone/androgen & testosterone (Leydig cells)
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Cells of the neurohypophysis?
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pituicytes, Herring bodies
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Mineralcorticoids
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act on distal renal tubules, gastric mucosa, colon & salivary & sweat glands - stimulate reabsorption of sodium by epithelial cells
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Glucocorticois
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affect metabolism of carbohydrates - stimulates production of glucose/gluconeogenisis. Also suppress immune response.
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DHEA
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dehydroepiandrosterone
sex hormone secreted by adrenal cortex - weak androgen that gets converted into testosterone |
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What controls the adrenal cortex?
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CRH (corticotropin-releasing hormone), ACTH (corticotropin). Free glucocorticoids may inhibit ACTH secretion.
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Islets of Langerhans
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alpha = glucagon
beta = insulin D = somatostatin (inhibits other islet cell hormones through paracrine action). Located in cell of pancreas. |