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22 Cards in this Set

  • Front
  • Back
What are the three layers of the Adrenal Cortex?
Zona glomerulosa
Zona fasciculata
Zona reticularis
What does the zona glomerulosa secrete?
mineralcorticoids (aldosterone)
What does the zona fasciculata secrete?
glucocorticoids (cortisol and corticosterone)
What does the zona reticularis secrete?
Androgens
What factor acts on the aona glomerulosa?
Angiotensin and corticotropin (ACTH)
What factor acts on the zona fasciculata and the zona reticularis?
Corticotropin
What type of cell exists only in the neurohypophysis?
Pituicytes
What hormone stimulates testosterone secretion?
LH
What do the Sertoli cells of the testis produce?
Sertoli cells are stimulated by FSH to secrete androgen-binding protein which binds with testosterone to feedback to the pituitary.
What are chromaffin cells?
Chromaffin cells are endocrine cells of the adrenal medulla. They secrete catecholamine hormones.
What is the embryological origin of the adenohypophysis and neurohypophysis?
Ectoderm of the roof of the mouth becomes the Pars distalis, pars tuperalis, and median eminence. The floor of the diencephalon becomes the Pars nervosa.
adenohypophysis
anterior pituitary
neurohypopysis
posterior pituitary (pars nervosa & infundibulum)
ACTH
corticotropin
stimulates secretion by adrenal glands
FSH stimulates what?
Estrogen/spermatogenesis
LH stimulates what?
Progesterone/androgen & testosterone (Leydig cells)
Cells of the neurohypophysis?
pituicytes, Herring bodies
Mineralcorticoids
act on distal renal tubules, gastric mucosa, colon & salivary & sweat glands - stimulate reabsorption of sodium by epithelial cells
Glucocorticois
affect metabolism of carbohydrates - stimulates production of glucose/gluconeogenisis. Also suppress immune response.
DHEA
dehydroepiandrosterone
sex hormone secreted by adrenal cortex - weak androgen that gets converted into testosterone
What controls the adrenal cortex?
CRH (corticotropin-releasing hormone), ACTH (corticotropin). Free glucocorticoids may inhibit ACTH secretion.
Islets of Langerhans
alpha = glucagon
beta = insulin
D = somatostatin (inhibits other islet cell hormones through paracrine action). Located in cell of pancreas.