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37 Cards in this Set

  • Front
  • Back
Where do the Secretions of the Endocrine System go?
-CT around the Glands
-Diffuses into blood
-Blood carries hormones to targets
Why do Endocrine Glands have lots of Capillaries around them?
To carry hormones to their targets
What are some characteristics of Steroid-Producing Cells?
-Foamy Appearance
-Lots of SER - Convert Cholesterol to Steroids
-Lots of Mitochondria
Tubular Cristae
What are some characteristics of Peptide-Producing Cells?
-Secretory Granules
-Lots of RER
What is the Pituitary Gland Surrounded by?
Embedded in Bone
How does the Pituitary Develop?
-Oral Ectoderm Outpouch
-Meets Downgrowth of Floor of Diencephalon (Neuroectoderm)
-Grows Caudally and stays attached to brain within sphenoid bone
What is each part of the Pituitary Derived from?
-Anterior - Oral Ectoderm
-Posterior - Neuroectoderm
Hormones of the Anterior Pituitary.
FLAT PEG
What is the Neurohypophysis?
Posterior Pituitary
What is the Adenohypophysis?
Ant. Pit.
Which part of the Pituitary receives Neural Tracts? What does mean for staining?
-Post. Pit. - Pars Nervosa
-Stains Lighter
What are the 3 regions of the Ant. Pit.?
-Pars Distalis - Largest
-Pars Tuberalis - Neck Region Between the 2
-Pars Intermedia - Region Between Ant. and Post. Pit., thin band
How does the ant. pit. get its stimulus?
Hypophyseal Portal System
Why does the Posterior Lobe Stain Lighter than the Anterior?
Contains Nerve Tracts
Describe the Pars Distalis.
-Bulk of the Ant. Pit.
-Lots of CT
-Irregular Cords or Epithelial Cells
-Acidophils, Basophils, Chromophobes
Where is the Pars Tuberalis Found?
-Ant. Pit.
-Goes around the Stalk that forms to help form the Posterior Lobe
What the fuck is the Pars Intermedia?
-Between Ant. and Post. Pit.
-Contains Colloidal Cysts
-MSH - Melanocyte-Stimulating Hormone
-Beta-Lipoprotein - LPH
What are some Acidophils? How do they stain?
-Pink
-Somatotrophs - GH
-Lactotrophs - Prolactin
What are some Basophils? How do they stain?
-Clear
-Thyrotrophs - TSH
-Gonadotrophs - FSH, LH
-Corticotrophs - ACTH
What are the Blue Cells in the Ant. Pit.?
-Nucleus of Chromophobes
-Basophils are stained Clear to Light Blue
What are Chromophobes thought to be?
Resting or Emptied Chromophils
What type of Ant. Pit. Cells will have more Granules?
Acidotrophs
Why is it important pathologically to identify different cells in Ant. Pit?
To tell which cells might be affected and which enzymes might be deficienct
Describe the Capillaries in Endocrine Tissue. Why are they this way?
-Fenestrated
-Large Fenestration
-Peptides and other Hormones need a Larger window to get through
What kind of Nerve Tracts is the Post. Pit. Receiving? Where are they from?
-Unmyelinated
-Supraoptic and Paraventricular Nuclei of the Hypothalamus
Where do we find the Terminal of Unmyelinated axons in the Post. Pit?
Pars Nervosa
What are Herring Bodies? Where are they found?
-Ends of Terminals of Unmyelinated Axons in Post. Pit.
-Store: ADH and Oxytocin
Where are ADH and Oxytocin Synthesized? Stored?
-Hypothalamus
-Post. Pit.
What are Pituicytes?
-Branched Glial Cells
-Support Cells
-Look like Nervous Tissue
Compare the Staining of the Pars Intermedia and Pars Nervosa.
-Intermedia - Darker
-Nervosa - Light and Wavy from Nerve Tracts
Where do Hormones sit in the Post. Pit before they Diffuse into Blood Vessels? How does this area stain?
-Herring Bodies
-Bluish
How do Pituicytes stain?
Darker
Where is Melatonin Produced? Where is it involved in?
-Pineal Gland
-Circadian Rhythms, Sleep, Gonadrotrophin Release
What is the Parasympathetic Stimulus on the Pineal Gland?
Light
Where are the Nuclei of the Nerve Tracts in the Posterior Pit.?
They're not here! They are in the Hypothalamus. Only Axons are found here.
What is often the distinguishing characteristic of Pinealocytes?
-Large
-2 Nucleoli - Dark Dots
What do Astrocytes in the Pineal Gland look similar to?
-Macrophages
-Neural Tissue