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29 Cards in this Set

  • Front
  • Back
ID a classic lobule
Lobules vary from 3 to seven or 8 sided, but the rare classical hexagon is rarely seen. The lobule is outlined by connective tissue, but in humans this outline is rarely seen.
ID a portal canal
Portal canals are located at the vertices of the classic lobule consisting of an artery/vein arteriole/venule, lymphatic duct, bile duct, and autonomic nerves. A continuous layer of hepatocytes surrounds the portal canal as a wall ("mura")
ID a portal vein
Largest lumen in the portal canal. Contains a thin tunica media and a thick tunica adventitia.
ID a hepatic artery
Thick tunica media with visible smooth muscle.
ID a bile duct
Lined with simple cuboidal epithelium.
ID a lymphatic duct
Consists of a thin endothelial layer
ID a central vein
At the center of a lobule. In a pig there is a lot more CT surrounding the central vein. Lines of sinusoids are directed towards the central canal like spokes on a bicycle .
ID a sinusoid
also known as discontinuous capillaries are in between the plates of hepatocytes. They are lined with endothelium.
ID a hepatic artery
Thick tunica media with visible smooth muscle.
ID a bile duct
Lined with simple cuboidal epithelium.
ID a lymphatic duct
Consists of a thin endothelial layer
ID a central vein
At the center of a lobule. In a pig there is a lot more CT surrounding the central vein.
ID a sinusoid
also known as discontinuous capillaries are in between the plates of hepatocytes. They are lined with endothelium and drain into the central vein.
ID endothelial cells
These line the sinusoids and contain reticular fibers that may have a unique stain
ID lipocytes
Clear cytoplasms that look like minuature unilocular fat cells. These cells store vitamin A.
ID sublobular veins
Sublobular veins are much larger than central veins and can be found between lobules surrounded by connective tissue. There are no sinusoids draining into these veins that are surrounded by a thin layer of tunica adventitia.
ID the space of Disse in the LM
The space of disse is located between the hepatocytes and the sinusoids see HA 10.
ID the Bile Canaliculi.
In longitudinal sections they are seen outlining the borders between hepatocytes. In cross section they appear as circles at the edges of hepatocyte boundaries.
ID the Kupffer cells
Kupffer cells are macrophages that form part of the lining of the sinusoid and bulge into the sinusoid lumen. They phagocytose trypan blue and so become easily distinguishable with that stain.
ID the epithelium of the gall bladder in the light microscope
Simple columnar epithelium with microvilli and visible terminal bars (junctional complex). Lateral interdigitations are evident by the dilations of the lateral intercellular spaces.
ID the lamina propria
loose connective tissue below the epithelium. Contains fenstrated capillaries, small venules, lymphocytes and plasma cells (no lymphatics). Lymphatics are different from lymphocytes.
ID the muscularis externa
This smooth muscle is randomly arranged unlike that of the gut. Its boundaries with the LP are quite distinct.
ID the fibrosa
Located in parts of liver that are not covered with visceral peritoneum (the side interfacing with the liver). Below the muscularis externa, it cotins large blood vessels, adipose tissue and sections of dense irregular CT.
ID the serosa
On the free side of the gall bladder. The layers of Lamina Propria and, muscularis externa and serosa are much thinner than the side with fibrosa. One is able to see the simple squamous epithelium lining the fibrosa.
ID the acinar cells
Very polarized cells. The apex is filled with acidophilic secretory granules that stain lightly and they have a basophilic base that stains darkly with hematoxylin because of rough ER. Acinar cells are pyramidal and arranged around a small lumen.
ID the centroacinar cells
Centroacinar cells represent the beginning of a duct within the acini. This arrrangement is unique to the pancreatic exocrine system. In the LM one can visualize the nucleus of the centroacinar cell at the center of the acinus. The arrangement looks like a flower with the acinar cells as the petal and the centroacinar cell nucleus as the stamen/pistil.
ID the intercalated ducts (intralobular ducts)
Intercalated ducts can be found amongst the acini lined with simple squamous epithelium. They are easily distinguished from the pyramidal acinar cells as shown in slide 27.
ID the interlobular ducts
Inter lobular ducts are are distinguished from intralobular (intercalated) by the connective tissue sheath that surrounds them. Interlobular ducts are lined with simple columnar/cuboidal epithelium.
ID the islets of Langerhans
The islets are highly vascularized and can be distinguished from the acini by their nonpolarized swarms of cells.