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12 Cards in this Set
- Front
- Back
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describe activation of b and t cells and their function:
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cytotoxic T cells always require a helper T cell's interlukens, act ove ra short distance, make PERFORINS.
B cells, usually require t-helper cells, act by producing antibodies and can work over long distances. |
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What are the relative concentration of lymphocytes?
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70% are t cells, B are 25%
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what cells are considered part of the inante response?
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macrophages, neutrophils, NK cells. Also boring things like skin and mucous membranes.
eosinophils Note that macrophages are also considered APC's which makes them a part of the adaptive system as well |
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what are interferons?
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small virus interefering molecules made by macroophages and fibroblasts after being stimmed by an infected cell.
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what should we know about MHCI and II?
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MHC I should be on all cells, MHC II should be on antigen presenting cells.
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Where do B and T cells gain immunocompetence?
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B cells develop and gain competence in the bone marrow - t cells develop in bone marrow but have to move to thymus to get smart.
respond to antigens from secondary sites (lymph nodes and spleen and MALT). |
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Epithelial reticular cells?
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Live in thymus, 6 kinds. framework for developing t cells. Look like little rings.
Responsible for t-cell maturation |
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Tell me about the thymus
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antigen free environment
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Is there lymph in the thymus?
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no, it's an antigen free environment and has only vasculature
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lymph nodes: where are B and T cells?
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B cells are in the cortex (BC)
T cells are in the medulla (TM) |
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Which lymphoid tissue inolved in antibody formation?
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lymph nodes are where b cells live. spleen. malt
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thymus vs. lymph node cortex
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Cortex of the thymus is very dark because it's full of T cells.
In the lymph node, the outer cortex is full of B cells, but the inner paracortex is full of T cells. |
