Histology

Front 1

Transport of material into cells:

Back 1

phagocytosis: engulf large particles, form phagosomes
- pinocytosis: engulf soluble material in a non-specific fashion
- receptor mediated endocytosis: specific, involving coated pits lined
with clatherin
- all can fuse with primary lysosomes.
- Residual body can be exocytosed or form lipofuscin

Front 2

phagocytosis:

Back 2

engulf large particles, form phagosomes

Front 3

pinocytosis

Back 3

engulf soluble material in a non-specific fashion

Front 4

receptor mediated endocytosis:

Back 4

specific, involving coated pits lined
with clatherin

Front 5

Lysosomes

Back 5

membrane bound
- contain acid hydrolases, pH 5.0
- degrade just about everything
- 2 functions
o degrade substance taken in by cell
o degrade worn out organelles
- new lysosomes: primary lysosomes
- lysosomes digesting: secondary lysosomes
- lysosomes unable to completedigestion: residual bodies
- autophagy: consumption of self

Front 6

primary lysosomes；
secondary lysosomes

Back 6

new lysosomes: primary lysosomes
- lysosomes digesting: secondary lysosomes

Front 7

residual bodies

Back 7

lysosomes unable to completedigestion

Front 8

Mitochondria

Back 8

0.5-1.0 wide x 5-10 um long
- ATP synthesis by oxidative phosphorylation
- Double unit membrane (7 um) separated by Intramembranous space
- Number of mitochondria related to energy requirements
- Cristae increase inner membrane surface area
o Shelf like
o Finger like…more area
o Covered with elementary particles: connect electron transport
to phosphorylation
- “cytosol” of mitochondrion called matrix
o matrix granules divalent cation store
o contains both RNA and DNA and ribosome
-duplicate by fission

Front 9

Cristae

Back 9

increase inner membrane surface area
o Shelf like
o Finger like…more area
o Covered with elementary particles: connect electron transport
to phosphorylation

Front 10

Pigment:
exogenous
endogenous

Back 10

ubstance that processes its own colour
o Exogenous (from without)
ƒ Carotene (plants)
ƒ Dusts (smoking)
ƒ Minerals (tattoo)
o Endogenous (from within)
ƒ Hemoglobin (hemosiderin, bilirubin, biliverdin)