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4 Cards in this Set
- Front
- Back
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Crescentic glomerulonephritis
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proliferation of the parietal cells of Bowman's capsule and also infiltration of macrophages, producing a crescent-like mass in most glomeruli
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Congenital Nephrotic Syndrome
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caused by a mutation in the nephrin gene leading to the absence or malfunciotn of the podocyte slit filtration diaphragm.
affected children have massive proteinuria and edema |
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Autosomal Dominant Polycystic Kidney Disease (ADPKD)
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Results from mutations in either of two genes: PKD1 and PKD2, encoding polycystin1 and polycystin2 proteins
These proteins are found predominantly in the cilium of principal cells of the collecting ducts |
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Transitional Cell Carcinoma (TCC)
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Most common bladder cancer, male dominant,
replacement of normal epithelial cells with ones that are enlarged crowded with enlarged hyperchromatic nuclei and prominent mitotic figures; epithelium is not thickened Epithelium changes are likely to progeress to invasive |
