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8 Cards in this Set
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- 3rd side (hint)
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The antimitotic alkaloid colchicine (used in = ) binds specifically to tubulin, and when the complex tubulin–colchicine binds to microtubules, it prevents the addition of more tubulin |
gout
WHat is the Rx = |
***colchicine
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Another alkaloid that interferes with the mitotic microtubule is __?__, (used in breast cancer) which accelerates the formation of microtubules but at the same time stabilizes them
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taxol
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Alkaloids, __?__ & __?__
(used in leukemias), acts by depolymerizing formed microtubules and, in a second step, aggregating to form paracrystalline arrays of tubulin. |
vinblastine
vincristine |
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Microfilaments
. Actin filaments are associated with myosin and form a |
purse-string
" ring of filaments whose constriction results in the cleavage of mitotic cells. |
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T/F
actin filaments are found scattered in what appears to be an unorganized fashion within the cytoplasm |
True
*** **Cytochalasin B & cytochalasin D prevent actin polymerization inhibiting lymphocyte migration, phagocytosis and cell division cytokinesis. = what is it = |
**Cytochalasin B
& cytochalasin D |
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Cilia
*** Stabalization of cilia & principle elements there in is = It allows axonemal bending |
tektin
is a scophold for micro tubules |
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Kartageners syndrome
aka = |
Immotile Cilia Syndrome
Causes what 3ct = |
Immotile Spermatozoa
Male infertility DUH Chronic Respiratoty Inf |
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*** know the enlarged microtubule Doublet
is affiliated with what structure = |
Cilia
It has what structure = |
a double microtubule
9 + 2 Pattern THere is also a 9 + 3 pattern The Micro tubule doublet is made by sharing their heterodimers which connect them, |
