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44 Cards in this Set

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Q. Lymphatic Cells:
Lymphocytes, T Lymphocytes, B Lymphocytes, NK Cells, Antigen-Presenting Cells
Q. Lymphatic tissue & Organs:
Lymphatic Vessels, Diffuse Lymphatic Tissue, Lymphatic Nodules, Lymph Nodes, Thymus, Spleen, Bone Marrow
Q. Lymphatic System Traits:
Lymphatic Organs and Tissues constitute the immune system. Lymphatic tissues are places where the lymphocytes proliferate, differentiate, and mature.
Q. Immune Defense types:
Nonspecific Defenses, or Specific Defenses.
Q. Nonspecific Defense:
consist of physical barriers, e.g. the skin and mucous membranes. Also consist of chemical substances that neutralize foreign cells.
Q. Specific Defenses
antibody or humoral response, cellular immune response
Q. antibody or humoral response:
The production of proteins that mark invaders for destruction by other immune cells.
Q. The cellular immune response:
This targets transformed and virus-infected cells for destruction by lymphocytes
Q. T-Cells(T-lymphocytes):
T lymphocytes arise from lymphocytes that are carried from the bone marrow to the thymus gland, where they mature and become immunocompetent.
Q. T Cells kill by:
cytotoxic action or by activating B-cells
Q. B-Cells:
Come from bone marrow. They comprise 20-30% of blood lymphocytes. They are involved in the production and secretion of circulating antibodies.
Q. Nk Cells:
Develop from bone marrow. Constitute 5-10% of blood lymphocytes. They release perforins and fragmentins which induce these cells to self-destruct.
Q. Antigen Presenting cells:
break down antigens to peptides which bind to MHC II molecules. Most are mononuclear phagocytes
Q. MHC 2:
found only in macrophages
Q. Diffuse Lymphatic Tissue:
The alimentary canal, respiratory passages, and genito-urinary tract are guarded by accumulations of lymphatic tissue not enclosed by a capsule
Q. Lymphocytes are located:
in the lamina propria of these tracts
Q. Plasma cells and eosinophils in this tissue indicates:
antibody production and chronic inflammation and hypersensitivity respectively
Q. MALT & GALT Gut-associated lymphatic tissue:
These cells intercept antigens and initiate an immune response by traveling to regional lymph nodes where they undergo proliferation and differentiation into effector B and T lymphocytes
Q. Primary Lymphoid Organs:
Fetal Liver, Prenatal & Postnatal Bone Marrow, Thymus
Q. Primary Lymphoid Organs are responsible:
development and maturation of lymphocytes into mature immuno- competent cells, not to facilitate immune responses.
Q. Secondary Lymphoid Organs:
Lymph Nodes, Spleen, Mucosa Associated Lymphoid Tissue (MALT and GALT), Postnatal Bone Marrow
Q. Thymus:
endocrine gland that lies mostly in the superior mediastinum(above the heart)
Q. Thymus During childhood:
very active, but from puberty to old age undergoes progressive atrophy and produces declining numbers of mature T cells
Q. Thymus produces:
number of hormones that support proliferation and differentiation of T cell progenitors
Q. Thymus contain:
densely packed differentiating T cells
Q. 3 hormones produced by cortex of thymus:
thymosin, thymulin, and thymopoietin and some differentiation-inducing cytokines
Q. Thymus Type 1 cell :
separate the capsule and trabeculae from the cortex and surround cortical vascular elements
Q. Thymus Type 2 cell:
Type II cells form desmosomal junctions with each other to form small compartments full of lymphocytes
Q. Thymus Type 3 cells:
form occluding junctions that isolate the cortex from the medulla
Q. Thymus Type 4 & 5:
structural support
Q. Thymus Type 6:
Hassal’s corpuscle, whose function is unknown
Q. Lymphoid Follicles:
The loose connective tissue of the epithelial linings of the digestive, respiratory, and urinary tracts commonly contains lymphoid follicles or nodules
Q. Lymphoid Follicle Location:
The Tonsils, Peyer’s Patches,The Appendix
Q. Lymphoid Follices diffuse through:
lamina propria
Q. Lymphoid follicle structure:
flat epithelial cells (M cells or FAE cells) that ingest antigen and deliver them to APC’s of the GALT
Q. Lymph Nodes:
Numerous macrophages remove bacteria and particulate matter. Afferent lymph vessels penetrate the capsule, efferent vessels leave the hilum
Q. B cells in lymph nodes:
are present in the outer zone of the cortex. Germinal centers are sites of antigen-elicited B cell proliferation, also follicular dendritic cells are present
Q. Medullary Cords of lymph nodes:
contain large numbers of plasma cells that release their antibodies into the efferent lymph
Q. Plasma cells live for how long:
3 days in the medullary cords, liberating their antibodies. Some B cells are also found there
Q. activated B cells in the cortex form:
Plasma cells
Q. Spleen:
The largest lymphoid organ, contains only efferent lymphatics, dense fibroelastic capsule
Q. Spleen Functions:
It is the chief source of circulating antibodies. Disposal of defective red blood cells
Q. Spleen white pulp:
primarily lymphoid follicles
Q. Spleen Red pulp removes:
Worn out blood cells, Platelets, Suspended particulate matter,