Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
44 Cards in this Set
- Front
- Back
Q. Lymphatic Cells:
|
Lymphocytes, T Lymphocytes, B Lymphocytes, NK Cells, Antigen-Presenting Cells
|
|
Q. Lymphatic tissue & Organs:
|
Lymphatic Vessels, Diffuse Lymphatic Tissue, Lymphatic Nodules, Lymph Nodes, Thymus, Spleen, Bone Marrow
|
|
Q. Lymphatic System Traits:
|
Lymphatic Organs and Tissues constitute the immune system. Lymphatic tissues are places where the lymphocytes proliferate, differentiate, and mature.
|
|
Q. Immune Defense types:
|
Nonspecific Defenses, or Specific Defenses.
|
|
Q. Nonspecific Defense:
|
consist of physical barriers, e.g. the skin and mucous membranes. Also consist of chemical substances that neutralize foreign cells.
|
|
Q. Specific Defenses
|
antibody or humoral response, cellular immune response
|
|
Q. antibody or humoral response:
|
The production of proteins that mark invaders for destruction by other immune cells.
|
|
Q. The cellular immune response:
|
This targets transformed and virus-infected cells for destruction by lymphocytes
|
|
Q. T-Cells(T-lymphocytes):
|
T lymphocytes arise from lymphocytes that are carried from the bone marrow to the thymus gland, where they mature and become immunocompetent.
|
|
Q. T Cells kill by:
|
cytotoxic action or by activating B-cells
|
|
Q. B-Cells:
|
Come from bone marrow. They comprise 20-30% of blood lymphocytes. They are involved in the production and secretion of circulating antibodies.
|
|
Q. Nk Cells:
|
Develop from bone marrow. Constitute 5-10% of blood lymphocytes. They release perforins and fragmentins which induce these cells to self-destruct.
|
|
Q. Antigen Presenting cells:
|
break down antigens to peptides which bind to MHC II molecules. Most are mononuclear phagocytes
|
|
Q. MHC 2:
|
found only in macrophages
|
|
Q. Diffuse Lymphatic Tissue:
|
The alimentary canal, respiratory passages, and genito-urinary tract are guarded by accumulations of lymphatic tissue not enclosed by a capsule
|
|
Q. Lymphocytes are located:
|
in the lamina propria of these tracts
|
|
Q. Plasma cells and eosinophils in this tissue indicates:
|
antibody production and chronic inflammation and hypersensitivity respectively
|
|
Q. MALT & GALT Gut-associated lymphatic tissue:
|
These cells intercept antigens and initiate an immune response by traveling to regional lymph nodes where they undergo proliferation and differentiation into effector B and T lymphocytes
|
|
Q. Primary Lymphoid Organs:
|
Fetal Liver, Prenatal & Postnatal Bone Marrow, Thymus
|
|
Q. Primary Lymphoid Organs are responsible:
|
development and maturation of lymphocytes into mature immuno- competent cells, not to facilitate immune responses.
|
|
Q. Secondary Lymphoid Organs:
|
Lymph Nodes, Spleen, Mucosa Associated Lymphoid Tissue (MALT and GALT), Postnatal Bone Marrow
|
|
Q. Thymus:
|
endocrine gland that lies mostly in the superior mediastinum(above the heart)
|
|
Q. Thymus During childhood:
|
very active, but from puberty to old age undergoes progressive atrophy and produces declining numbers of mature T cells
|
|
Q. Thymus produces:
|
number of hormones that support proliferation and differentiation of T cell progenitors
|
|
Q. Thymus contain:
|
densely packed differentiating T cells
|
|
Q. 3 hormones produced by cortex of thymus:
|
thymosin, thymulin, and thymopoietin and some differentiation-inducing cytokines
|
|
Q. Thymus Type 1 cell :
|
separate the capsule and trabeculae from the cortex and surround cortical vascular elements
|
|
Q. Thymus Type 2 cell:
|
Type II cells form desmosomal junctions with each other to form small compartments full of lymphocytes
|
|
Q. Thymus Type 3 cells:
|
form occluding junctions that isolate the cortex from the medulla
|
|
Q. Thymus Type 4 & 5:
|
structural support
|
|
Q. Thymus Type 6:
|
Hassal’s corpuscle, whose function is unknown
|
|
Q. Lymphoid Follicles:
|
The loose connective tissue of the epithelial linings of the digestive, respiratory, and urinary tracts commonly contains lymphoid follicles or nodules
|
|
Q. Lymphoid Follicle Location:
|
The Tonsils, Peyer’s Patches,The Appendix
|
|
Q. Lymphoid Follices diffuse through:
|
lamina propria
|
|
Q. Lymphoid follicle structure:
|
flat epithelial cells (M cells or FAE cells) that ingest antigen and deliver them to APC’s of the GALT
|
|
Q. Lymph Nodes:
|
Numerous macrophages remove bacteria and particulate matter. Afferent lymph vessels penetrate the capsule, efferent vessels leave the hilum
|
|
Q. B cells in lymph nodes:
|
are present in the outer zone of the cortex. Germinal centers are sites of antigen-elicited B cell proliferation, also follicular dendritic cells are present
|
|
Q. Medullary Cords of lymph nodes:
|
contain large numbers of plasma cells that release their antibodies into the efferent lymph
|
|
Q. Plasma cells live for how long:
|
3 days in the medullary cords, liberating their antibodies. Some B cells are also found there
|
|
Q. activated B cells in the cortex form:
|
Plasma cells
|
|
Q. Spleen:
|
The largest lymphoid organ, contains only efferent lymphatics, dense fibroelastic capsule
|
|
Q. Spleen Functions:
|
It is the chief source of circulating antibodies. Disposal of defective red blood cells
|
|
Q. Spleen white pulp:
|
primarily lymphoid follicles
|
|
Q. Spleen Red pulp removes:
|
Worn out blood cells, Platelets, Suspended particulate matter,
|