Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
|
intermediate filament diameter
|
10 nm
|
|
|
name the 4 classes of intermediate filaments
|
keratins, vimentin&vimentin-like, neurofilaments, lamins
|
|
|
how many IF proteins and how many class
|
50 proteins, 4 classes
|
|
|
where are the IF keratins
|
cytoplasms of epithelial cells, they are cytokeratins (acid and basic)
|
|
|
what are the vimentin and vmentin-like proteins
|
vimentin, desmin, GFAP (glial fibrillary acidic protein), peripherin, nestin
|
|
|
where is vimentin
|
fibroblasts, whole blood cells, mesenchymal cells
|
|
|
where is desmin
|
muscle
|
|
|
where is GFAP
|
glial cells
|
|
|
where is peripherin
|
peripheral nerve
|
|
|
where is nestin
|
neural stem cells
|
|
|
where are neurofilament proteins
|
neurons
|
|
|
what proteins are in the lamins class and where are they located
|
lamin A/C, and lamin B, in nucleus
|
|
|
disease causing blistering of skin from mutations in keratin genes
|
epidemolysis bullosa simplex(EBS)
|
|
|
disease w/ accumulation and abnormal assembly of neurofilaments leading to loss of motor neurons
|
amyotrophic lateral sclerosis (ALS, Lou Gehrigs disease
|
|
|
chemical causing diasassembly of nerves
|
acrylamide
|
