Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
27 Cards in this Set
- Front
- Back
|
What are focal adhesions
|
attachment of cells to extracellular matric
|
|
|
transmembrane proteins for focal adhesions
|
inegrins
|
|
|
large actin bundles attached to integrins
|
stress fibers
|
|
|
actinb binding proteins that attach to integrin
|
vinculin, talin
|
|
|
what binds acting to transmembrane proteins
|
dystrophin
|
|
|
cell-cell adhesion transmembrane protein
|
cadherin at adherens jxns
|
|
|
how does actin for complexes with cadherin
|
through catenin
|
|
|
thin projections of pm from actin
|
microspikes/filopodia
|
|
|
sheetlike extensions of the cell at leading edge of movement by actin
|
lamellopodia
|
|
|
actin modification for endocytosis
|
invaginations
|
|
|
does cilia have actin
|
no
|
|
|
does microvilli have actin
|
yes and fimbrin too
|
|
|
does stereocilia have actin
|
yes
|
|
|
action of phalloidin
|
binds to F-actin preventing dissociation
|
|
|
fxn of cytochalasin
|
binds to the plus end blocking F-actin elongation
|
|
|
fxn of swinholide
|
severs actin filament
|
|
|
fxn of latrunculin
|
binds subunits and prevents polymerization of actin
|
|
|
2 types of muscular dystrophy
|
beckers and duchennes
|
|
|
non-rbc cortical actin binding proteins
|
fodrin and dystrophin
|
|
|
abp in rbs providing support for cytoskeleton
|
spectrin
|
|
|
abp making meshwork (cortical acting) supports cell movement and shape
|
filamin
|
|
|
abp that forms actin bundles in microvilli (tight)
|
fimbrin
|
|
|
abp that forms actin bundles in contractile ring of dividing cells
|
alpha-actinin
|
|
|
key protein responsible for dissociation of F-actin, binds to ADP-actin
|
coflin
|
|
|
reverses cofilin, stimulates exchange of ADP for ATP
|
profilin
|
|
|
abp that severs actin filaments
|
gelsolin
|
|
|
abp nucleating actin
|
Arp 2/3
|
