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112 Cards in this Set
- Front
- Back
What 2 portions are included in the respiratory system?
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conducting and respiratory portions
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Air is relatively what 2 things to all living things?
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toxic and vital
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What must happen to air during passage to the lungs so gas exchange can take place?
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conditioned
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What are 2 funcitons of respiratory system.
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olfaction-sense of smell
vocalization |
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the function of the respiratory system warming, filtering and humidifying air is what?
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conditioning of air
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The funciton of the respiratory system that involves bringing air fromt the outside deep into the body to site of exchange is what?
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conduction of air
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The respiratory tree is ventilated by ______ ______ pf tje chest wall by muscles of he thoracic cage and diaphragm?
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inspiratory movements
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What is accomplished by elastic elements and mm of the air passage?
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expiration
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At the end of the respiratory tree what occurs?
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gas exchage
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The number of active capillaries in the lung must be ____ or _____ to those of the systemic circulaiton or cardiovascular failure will ensue.
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equal or exceed
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Which portion of the respiratory system moisten, warm, filter the air in prep for gas exchange.
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conducting portion
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What have been removed (ideally) by the time air reaches the alveolus
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bacteria and infectious material
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What do infectious agents that reach the damp vascular lungs cuase?
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bronchitis, or pneumonia
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What serves to warm, humidify and filter the air.
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nasal cavity
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a special region of the roof of the nasal cavity mediates what?
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olfaction
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What is the anterior portion of the nasal cavity lined with skin (startified squamous epithelium)
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vestibule
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the course hairs of the vestibule are called what>
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vibrissae
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the purpose of the hairs of vestibule of nasal cavity are to what?
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filter out large particles
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The hairs of the vestiuble of the nasal cavity create what
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non-laminar air flow that help precipitate particulate matter
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What lines the nasal caivty
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respiratory epithelium, pseudostratified cilitated columnar epithelium
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What cell is abundant in nasal cavity
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goblet cells
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What of the respiratory epithelium is highly vascularized to warm incoming air
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lamina propria
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The lamina propria has many what that aid in filtration
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seromucous glands
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dust and other particulate matter are trapped b mucus from what?
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globlet cells, and mucous and serous secrtion of the glands
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Ciliary action of the nasal epithelium does what?
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carries mucous and particulate matter to pharynx to be swallowed or expectorated
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the lamina propria contains abundant what?
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lymphoid nodules
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What in the lamina propria are active in combating antigens carried by the air?
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lymphoid nodules
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What is produced by plasma cells and what is it transported across?
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plasma cells produce- secretory IgA
transported across- epithelium |
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Plasma cells produce IgE that binds to what>
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mast cells
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When challenged with antigen mast cells relaease what
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mediators of inflammation
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the release of histamine _______ permeabilit of small blood vessels cuase localized _______
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increases
swelling |
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What is in the nasal cavity warm inspired air and the nasal secretions begin the process of humidification
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venous sinusoids
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nasal secretions of the venous sinsoid begin the process of what?
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humidification
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What also help to disturb the flow of air and decreased particulate matter
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turbinates
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What is a tall pseudostratified columnar epithelium located near the roof of the nasal cavity
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olfactory epithelium
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Olfacotry cells are _____ neurons with a modified dendrite region composed of _____ ______
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bipolar
olfacotry vesicle |
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How large are the non-motile cilia that lie on the epithelial surface?
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6-8
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What molecules are specific for receptors on the cilia cause depolarization of the olfacotry cells in olfactory epithelium?
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odorant molecules
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What 2 cells are contained inolfactory epithelium?
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sustentacular and basal cells
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the sustentacular or basal cell appear to support the epithelium and insulate the olfactory cells.
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sustentacular cell
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the sustentacular or basal cell are short pyramidal cells, their apical region does not reach the surface of the epithelium
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basal cell
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what replace both olfactory and sustentacular cells
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basal cells
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air moves from the nasal cavit to what?
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pharynx
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what is the upper portion of and lower portion of the pharynx lined with?
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upper-respiratory epithelium
lower-stratified squamous epithelium |
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In the pharynx what is loose to dense irregular connective tissue with seromucous glands and lymphoid aggregations (pharyngeal tonsils)
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lamina prpria
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Air goes from nasal cavity to pharynx to what?
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larynx
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describe the larynx
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irregularly tubular and covered with pseudostratified epithelium
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waht 2 things support the larynx
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thyroid and cricoid hyaline cartilage
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What protects the larynx from food inhalation
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epiglottis
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What is a flap of tissue supported internally by elastic cartilage
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epiglottis
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The tissue covers the lingual and laryngeal sides of the epiglottis
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lingual- stratified squamous epithelium
laryngeal- pseudostratified ciliated epithelium (respiratory epithelium) |
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What project into the laryneal lumen?
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false and true vocal cords
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Do the true vocal cords lie below or above the false vocal cords
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below
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Which set of vocal cords consists of elastic ligaments connected to the striated vocalis mm
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true vocal cords
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what are the true vocal cords covered by?
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stratified squamous epithelium
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What is regulated by conrolled movement of air accross the true vocal chords
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sound
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What are used to adjust the tenstion of the vocal ligament
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vocalis and other laryngeal mm
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air move from larynx to what?
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trachea
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What is the most prominent characterist of the tracheA
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reinforcements of C-shaped hyaline cartilage rings
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What is the purpose of hyaline cartilage rings
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maintian open airway
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which direction do the open portion of teh c-shaped hyaline cart face
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rearward to the esophagus
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The opening of the c-shaped hyaline cart is bridged by what?
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fibroelastic ligament and smooth mm
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Contration of the smooth mm of the hyaline cart does what?
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narrows the passageway for increase force during coughing
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What lines the trachesa
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respiratory epithelium
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What is present just beneath the tracheal epithelium
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band of elastic fibers
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beneath the tracheal epithelium is elastic fibers then what
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glands and blood vessels
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The trachea bifurcates into 2 ____ ____ that connect to the _____
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primary bronchi
lungs |
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Prior to entering the lung the histology of the primary bronchus is similar to what
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trachea with cartilage rings
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The diameter of the primary bronchus is SMALLER OR LARGER and the walls are THINNER OR THICKER than the trachea
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smaller
thinner |
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what happens to the arrangement of the cartilage in the pimary bronchus after entering the lung?
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plates of cartilage surround subsequent segemnts of bronchi
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Which segment of bronchi reach major lobes of the lungs
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secondary bronchi
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What completely surround the lumina of intrapulmonary bronchi
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irregular plates of cartilage
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What becomes more prominant are is present as 2 layers spiraling in opp direction in secondary and tertiary bronchi
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smooth mm
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in the secondary and tertiary bronchi what occurs in the lamina propria and submucosa of the larger bronchi
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seromucous glands and lymphoid aggregations
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What epithelium is in secondary and tertiary bronchi
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respiratory epithelium
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What accompanies each secondary and tertiary bronchi?
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arteries, veins and lymphatic vessels
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What are distinguished by their lack of cartilage
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bronchioles
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What line bronchioles
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cuboidal epithelium
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Bronchioles contain few ____ _____ and many ___ ____
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few goblet cells
many ciliated cells |
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in bronchioles which cell type is find at deeper leves than are goblet cells
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ciliated cells
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In bronchioles what moves mucous toward throat
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ciliated cells
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What are the non-ciliated bronchilar cells contained in bronchioles
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clara cells
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Which type of cell acts a serous grandular cells but also appear to act as stem cells to replace other cell types in epithelium
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clara cells
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Which type of cell can aid in detoxifying noxious gases
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clara cells
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Does the lamina propria of the bronchioles have glands
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NO
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What are important in shortening of bronchioles and reduciton of the dead-air space during exhalation
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smooth mm and subepithelial elastic fibers
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in some forms of severe asthma ___ ____ of mm can close off the bronchioles inducing suffocation
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spastic contraction
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Chronic respiratory exposure to tobacco smoke can compromise what leading to what
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bronchial and bronchiolar elastic tissue leading to pulmonary emphysema
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What extend from fibroelastic connective tissue that is outside the smooth mm
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elastic fibers
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What do elastic fiber do during inhalation
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maintain open airways
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Which portion of the respiratory tract is highly vascularized, thin alveoli at the termination of the airways in the lungs, allow diffusion of gasses b/t air and blood
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respiratory portion
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What lead to the first level of respiratory protion of the lung
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terminal (conducting) bronchioles
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What are the first level of respiratory portion
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respiratiory bronchioles
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What have outpockets of alveoli
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respitory bronchiole
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waht are small sac like structures where gas exchange occurs
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alveoli
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What happen to the number of alveoli and width of bronchioles as the respiratory bronchioles extend deeper
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alveoli increase
broncioles narrow |
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What branch from the respiratory bronchioles
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alveolar ducts
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Alveolar duct have what type of walls
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irregular
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alveolar ducts are ____ air passages lined by alveoli
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narrow
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What is the diameter of alveoli
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~200um
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What are the primary site for gas exchange
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alveoli
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Capillary networks composed of large diameter capiliaries com in ____ _____ to air
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close proximity
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What seperate blood from air
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capillary endothelium, the alveolar epitheliuma nd the thin fused basal lamina between them
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What is the total thickness b/t air and blood
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.1-0.15um
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What is the total # of alveoli in adult humans and the gas exchange area
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300 million
140 m^2 |
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Which type of cells are very thin cells that make up most of the alveolar surface
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Type I cells squamous alveolar cells
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Waht type of cells are cuboidal and secre surfactant
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Type II cells
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What is a detergent like material consisting of phospholipids and lecithins
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surfactant
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Surfactant ___ surface tension at the alveolar surface and _____ the work required to inflat alveoli
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reduces
decrease |
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Type II cells can differient into what
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Type I cells
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Alveoli contain large number of active
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pulmonary macrophages
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What protect the alveoli by ingesting inhaled bacteria and other particles
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pulmonary macrophages
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