Histo Final Exam

Front 1

ID

Back 1

Embryonic (mucus) connective tissue

"Wharton's Jelly"

Front 2

ID

Back 2

Loose connective tissue stained with resorcin-fuchsin

1. Elastic fibers

2. Collagen fibers

Front 3

ID

Back 3

Plasma cells

(Loose connective tissue)
Function: antibody production

Front 4

ID

Back 4

Mast cell
(Loose connective tissue)

Stain: Toluidine Blue
(stains granules metachromatically)

Granules contain histamine, heparin sulfate

1. Small blood vessel in connective tissue

Front 5

ID

Back 5

Reticular fibers (Type III collagen fibers)

Hematopoietic tissue
Stained with silver salts

Front 6

ID

Back 6

Elastic tissue
(Dense connective tissue)
Stain: orecin & eosin

Found in ligamentum flava

Front 7

ID

Back 7

White adipose cells

Front 8

ID

Back 8

Brown adipose cells

Front 9

ID

Back 9

Dense irregular connective tissue

(Found in dermis layer of skin)

1. Fibroblasts

Front 10

ID

Back 10

Dense irregular connective tissue (closeup)

1. Fibroblast
2. Collagen fibers

Front 11

ID

Back 11

Dense regular connective tissue

Front 12

ID

Back 12

Hyaline cartilage

Stain: H & E

1. Condrocytes
2. Territorial matrix
3. Interterritorial matrix
4. Perichondrium
5. Lacunae
6. Isogenous groups

Front 13

ID

Back 13

Elastic cartilage

1. Chondrocyte
2. Perichondrium

Front 14

ID

Back 14

Elastic cartilage

Stain: resorcin fuchsin (stains the elastic fibers)

1. Elastic fibers
2. Perichondrium

Front 15

ID

Back 15

Fibrocartilage (magnified)

1. Collagen fibers Type I
2. Chondrocyte
3. Isogenous groups

Front 16

ID

Back 16

Fibrocartilage

1. Type I collagen fibers
2. Chondrocytes

(Found in the annulus fibrosus in the intervertebral disc)

Front 17

ID

Back 17

Bone (osteon)

1. Osteocytes
2. Haversian canals
3. Lamellae
4. Interstitial lamella
5. Osteon

Front 18

ID

Back 18

Osteoprogenitor cells in bone
(derived from mesenchymal cells)

Found in the lamellae, inner layer of periosteum, endosteum, and line the Haversian and Volkmanns' canals

Front 19

ID

Back 19

Osteoclasts

Large, multinucleated cell

Hyperparathyroidism will increase the numbers of these cells

Front 20

ID

Back 20

Bone (intramembranous ossification)

Process used by flat bones (skull, mandible, face, and clavicle)

1. Osteoblasts
2. Osteocytes
3. Bone

Front 21

ID

Back 21

Bone (enchondral ossification)

Located near articular cartilage and epiphyseal plates.

Chondrocytes inside bone swell and then calcify the matrix

1. Zone of reserve cartilage
2. Zone of proliferation
3. Zone of hypertrophy
4. Zone of calcified cartilage

Front 22

ID

Back 22

Bone (hyperparathyroidism)

Note the large number of osteoclasts

1. Osteoclasts
2. Resorption bays
3. Osteoblasts
4. Osteocytes

Front 23

ID

Back 23

Osteomyelitis (bone)

Inflammation and infection of bone marrow and bone)

1. Bony trabeculae
2. Lymphocytes

Front 24

ID

Back 24

Large multipolar neurons

Found in ventral horn of spinal cord

1. Oligodendrocyte

Front 25

ID

Back 25

Purkinje cells (neurons)

Found in cerebellum
Responsible for detection of body orientation

Front 26

ID

Back 26

Neuron in cortex (multipolar and pyramidal shaped)

1. Cell body
2. Axon
3. Dendritic processes

Front 27

ID

Back 27

Peripheral nerve cross section

1. Schwann sheaths
2. Perineurium
3. Cell wall of cytoplasm

Front 28

ID

Back 28

Peripheral nerve (longitudinal section)

1. Axon
2. Node of Ranvier

Front 29

ID

Back 29

Astrocyte - some have end feet

(GFAP staining using immunohistochemistry)

Glial fibriliary acidic protein

Fibrous type found in white matter

Protoplasmic type found in gray matter

Front 30

ID

Back 30

Oligodendrocyte

Stain: Silver

Front 31

ID

Back 31

Microglial cell

Smalles of the glia;

Mobile phagocytic cells

Front 32

ID

Back 32

Migroglial cells and oligodendrocytes (cross section)

1. Microglial cell (nuclei)
2. Oligodenrocyte

Front 33

ID

Back 33

Ependymal cells (Glial cell)

Line the ventricle and the central canals

Responsible for the blood-CSF barrier

1. Choriod plexus
2. Ependymal cells
3. CSF

Front 34

ID

Back 34

Sensory ganglion cells (cross section)

1. Satellite cells

Front 35

ID

Back 35

Lymphocytes, basophils, and neutrophils

1. Large lymphocyte
2. Basophil
3. Neutrophil

Front 36

ID

Back 36

Monocyte
(Histiocyte in the loose connective tissue)

Largest of white blood cells; nucleus is bean shaped)

Macrophages of the blood via interaction with Helper T cells

Front 37

ID

Back 37

Sickle cell anemia

Front 38

ID

Back 38

Eosinophils

Bi-lobed nuclei

Forms crystalloid bodies via MBP protein

Front 39

ID

Back 39

Lymphatic follicle in spleen

1. Red pulp
2. White pulp
3. Malpighian body

Lining of lymphatic nodules (PALS) Periartial lymphatic sheath

Front 40

ID

Back 40

Malpighian body in lymph nodule in spleen

Note: the perforation of a central artery

1. Red pulp
2. Malpighian Body
3. central artery

Front 41

ID

Back 41

Thymus (no nodules!)

1. Cortex
2. Medulla

Front 42

ID

Back 42

Hassal's corpuscle

Found in middle thymus

Epithelioreticular cells type VI
(Internal arch usually keratinized)

Front 43

ID

Back 43

Palatine tonsil

1. Lymphatic crypt

Front 44

ID

Back 44

Tonsil

1. Stratified squamous epithelium non-keratinized

2. Lymph nodules

Front 45

ID

Back 45

Lymph node

1. Capsule
2. Cortex (contains lymph follicles)
3. Medulla
4. Inner medulla (note- no lymph follicles in inner medulla

Front 46

ID

Back 46

Lymph node

1. Capsule
2. Subcapsular sinus (contains lymph)
3. Lymph follicles in cortex