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9 Cards in this Set
- Front
- Back
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apoptosis from loss of attachment
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anoikis
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method of death in nerve cells
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wallerian degeneration
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method of death in epithelial cells
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cornification
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Enzymes (proteases) active in apoptosis
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caspases
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does chromatin condense in necrosis
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no but nuclear envelop disrupts
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how do caspases being apoptosis
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signal (intra or extra)activates procaspases which active other procaspases leading to amplification of active caspases. The digenst key proteins killing cells
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2 main reasons for apoptosis
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-development (seperation of fingers, proper # of neurons etc)
-adult (viral infected, uterus change, barbituates) |
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what causes enlarged brain and webbed limbs
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knockout of caspase 9 and apaf 1
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what does adaptor protein (apaf-1) do?
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bind to procaspases and help activate them, it also binds to cytochrome c
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