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10 Cards in this Set
- Front
- Back
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new name for histiocytosis X
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Langerhans cell histiocytosis
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What are the cellular characteristics of the lesions of Langerhans cell histiocytosis?
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Langerhans cells with Birbeck granules
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Childhood histiocytoses Class I
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Langerans Cell histiocytosis
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Childhood histiocytosis Class II
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Familial eythophagocytic lymphohistiocytosis and infection-associated hemophagocytic syndrome; lesions involve infiltations of many organ systems
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Childhood histiocytosis Class III
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neoplastic proliferations; Malignant histiocytosis, acute monocytic leukemia
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cellular characteristics of Familial Erythophagocytic lymphohistiocytosis
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Morphologically nomal reactive macrophages with prominent eythophagocytosis
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cellular characteristics of lesions of Class III histiocytosis (Malignant Histiocytosis)
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neoplastic proliferation of cells with characteristics of monocytes/macrophages or their precursors
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What is a Langerhans cell?
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antigen-presenting cell of the skin
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What is a Birbeck granule?
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a tennis racket-shaped bilamellar granule in the cytoplasm of cells in lesions of LCH
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Class II histiocytoses ae characterized by accumulation
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of antigen-processing cells (i.e. macrophages)
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