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10 Cards in this Set

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  • Back
new name for histiocytosis X
Langerhans cell histiocytosis
What are the cellular characteristics of the lesions of Langerhans cell histiocytosis?
Langerhans cells with Birbeck granules
Childhood histiocytoses Class I
Langerans Cell histiocytosis
Childhood histiocytosis Class II
Familial eythophagocytic lymphohistiocytosis and infection-associated hemophagocytic syndrome; lesions involve infiltations of many organ systems
Childhood histiocytosis Class III
neoplastic proliferations; Malignant histiocytosis, acute monocytic leukemia
cellular characteristics of Familial Erythophagocytic lymphohistiocytosis
Morphologically nomal reactive macrophages with prominent eythophagocytosis
cellular characteristics of lesions of Class III histiocytosis (Malignant Histiocytosis)
neoplastic proliferation of cells with characteristics of monocytes/macrophages or their precursors
What is a Langerhans cell?
antigen-presenting cell of the skin
What is a Birbeck granule?
a tennis racket-shaped bilamellar granule in the cytoplasm of cells in lesions of LCH
Class II histiocytoses ae characterized by accumulation
of antigen-processing cells (i.e. macrophages)