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44 Cards in this Set

  • Front
  • Back
Cardiovascular system uses _____ to increase Oxygen transport rates.
Convective transport and diffusion
T/F Oxygen diffusion is at a rate sufficient for metabolism.

What is the rate?
True
<500 microns/s
Problems of mass and size of a multicellular organism
Transport
Locomotion
Communication
Benefits of being a multicellular organism
Specificity
Buffering from environment
Homeostasis
- Maintenance of extracellular environment within narrow limits suitable for cells
o pH, temperature, pO2, pCO2, osmolality, ionic composition and nutrients
What 6 transport functions does the cardiovascular system serve?
Oxygen
Nutrients – sugars, amino acids, lipids etc.
Metabolic wastes – CO2, Nitrogenous wastes, etc.
Hormones
Heat
Cells – transport for WBC and platelets
If a cow no longer had a functioning cardiovascular system what would happen to it in terms of heat?
The cow's body heat would increase dramatically and the cow would be very unhappy (dead)
The cardiovascular system is considered a closed system. What is the reality of the matter?
1.) Closed System – macroscopically, from rheological point of view
a. We have about 5-6 liters of blood which remains as a constant
b. In reality we do have mass exchange in the lungs and also due to the convective transport
In the cardiovascular system we have constant _____ but variable ____.
constant pressure, but variable flow
The pulmonary and systemic circuits are serviced by two pulsatile pumps that are set up in ______.
The pulmonary and systemic circuits are serviced by two pulsatile pumps that are set up in series
What is the benefit of the branching organization of the cardiovascular system - in particular what does this organization mean in terms of the organs being supplied with blood?
The organs are set up in parallel. Think of it like a water company. Everyone (organ) receives fresh water (blood). Each person can also receive a variable amount of water (varied amount of blood to each organ)
Unidirectional blood flow
directionally imparted by valves
a. Valves function passively
b. Ensure undirectionally
What ensures unidirectional blood flow in the blood vessels?
valves that function passively.
Cardiovascular system:

Compliant
Compliant – relates to the ease and distensibility of a structure. How easy is it to push a large amount of blood into this structure
Constant pressure and variable bloods supply provides _________ _________ blood flow.
continuous peripheral blood flow
Typical Aortic pressure:
Typical Pulmonary Artery Pressure:
Aortic Pressure: 120/80
Pulmonary Artery Pressure 25/15
Role

Arteriole
RESISTANCE

important in controlling blood flow to the tissues by exchanging bloods with capillaries, they offer the highest resistance.
Role

Capillaries
EXCHANGE

are much smaller than arterioles but there so many more that their net resistance is lower than in the arterioles. Exchange occurs here
Role

Venules
EXCHANGE
Role

Arteries
CONDUIT

are conduit vessels because they offer a rapid and low resistance pathway to the organs with very little pressure loss
Role

Veins
CAPACITANCE b/c Highly compliant

are called capacitance (2/3 to ¾ of the total volume) and are compliant so they hold most of the blood volume at any one time.
Compliant – relates to the ease and distensibility of a structure. How easy is it to push a large amount of blood into this structure
Vessel characteristics as they relate to resistance...

1.) Caliber
2.) Number of vessels
1.) Caliber – big vessels less resistance, small vessels large resistant

2.) How many vessels are there. More = lower resistance
Why is the resistance of capillaries smaller than arterioles?
Despite the fact that arterioles are larger than capillaries there are FAR MORE CAPILLARIES than arterioles, which = lower resistance in capillaries
What are the basic functions of the Kidneys?
1.) HOH excretion – body volume regulation
2.) Salt excretion
3.) Excretion of Metabolic wastes – nitrogenous waste and drugs
4.) Acid-base regulation
5.) Endocrine function:
a. Renin – Enzyme that forms angiotensin
b. Erythropoietin – hormone stimulates RBC production
c. 1,25-dihydroxyvitamin D
What are the Endocrine functions (3) of the Kidneys?
Endocrine function:
a. Renin – Enzyme that forms angiotensin
b. Erythropoietin – hormone stimulates RBC production
c. 1,25-dihydroxyvitamin D
How does the heart respond to neural, hormonal and local feedback?
Through
- Blood Volume
- Blood Pressure
- Blood Chemical Sensors
How do the Kidneys respond to neural, hormonal and local feedback?
- Reduce/Conserve blood volume
- Excrete/Conserve plasma electrolytes
Ventricular Ejections

Describe Right ventricular ejection in terms of changes to walls and movements.
o Shortening of the free wall
o Compression of the chamber (bellows action)
Ventricular Ejections

Describe left ventricular ejection in terms of contraction. What effect does this have on the RV
o Contraction reduces the diameter of the ventricular chamber and tends to shorten base to apex length of the ventricle.
o Causes a “right ventricular assist”, which reduces the volume in RV chamber
 Thus the RV can tolerate an infarct because of this assist
Ventricular Ejections

“right ventricular assist” is caused by what?
Contraction of the left ventricle
T/F The left ventricle has a thicker wall than the right ventricle.
True
T/F The left ventricle has a circular shape
True
What is the ventricular myocardium composed of?
It is composed of oblique and horizontal spiral muscles

These shorten the circumference (inner diameter) and long axis of the ventricle upon contraction.
Papillary muscles ensure that the ventricles contract _______.
simultaneously
What are the two semilunar valves and what structures are they between?
Pulmonic valve -> lungs to LA
Aortic Valve -> Tissue to RA
T/F Major coronary arteries lie on the surface and go into smaller arterioles into the heart
True
Heart contractions can _____ coronary blood flow. Constrictions of muscles generally _____ their own blood flow.
impede
Subsystems of the Heart

what are the 5 subsystems?
1.)Electrical conduction system
2.)Autonomic Nervous System
3.)Cardiac muscles
4.)Heart Valves
5.)Coronary circulation
Subsystems of the Heart

Electrical conduction system - what's the order?
SA and AV nodes; bundle of His, Purkinje Fibers
Subsystems of the Heart

Autonomic Nervous System
1.) Two systems
2.) _______ innervations of ventricular cells has great effect on the myocardium
1. Sympathetic and Parasympathetic innervations
2. Sympathetic
Subsystems of the Heart

Cardiac muscles are called
myocardium
Subsystems of the Heart

Heart Valves: 2 main types
Atrioventricular and semilunar valves
What are the two AV valves and what structures do they connect?
Tricuspid Valve: RA -> RV
Mitral (Bicuspid) Valve: LA->LV
What functional purpose do the papillary muscles and chordeae tendinaea serve?
PREVENT EVERSION OFBLOOD from ventricles to atria

The function of the (Tricuspid valve RA->RV) Chordeae Tendinaea and (Mitral- Bicuspid valve LA->LV – also have CT) Papillary muscle is to prevent eversion of blood from the ventricles back into the atrial chambers