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44 Cards in this Set
- Front
- Back
Cardiovascular system uses _____ to increase Oxygen transport rates.
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Convective transport and diffusion
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T/F Oxygen diffusion is at a rate sufficient for metabolism.
What is the rate? |
True
<500 microns/s |
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Problems of mass and size of a multicellular organism
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Transport
Locomotion Communication |
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Benefits of being a multicellular organism
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Specificity
Buffering from environment |
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Homeostasis
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- Maintenance of extracellular environment within narrow limits suitable for cells
o pH, temperature, pO2, pCO2, osmolality, ionic composition and nutrients |
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What 6 transport functions does the cardiovascular system serve?
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Oxygen
Nutrients – sugars, amino acids, lipids etc. Metabolic wastes – CO2, Nitrogenous wastes, etc. Hormones Heat Cells – transport for WBC and platelets |
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If a cow no longer had a functioning cardiovascular system what would happen to it in terms of heat?
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The cow's body heat would increase dramatically and the cow would be very unhappy (dead)
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The cardiovascular system is considered a closed system. What is the reality of the matter?
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1.) Closed System – macroscopically, from rheological point of view
a. We have about 5-6 liters of blood which remains as a constant b. In reality we do have mass exchange in the lungs and also due to the convective transport |
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In the cardiovascular system we have constant _____ but variable ____.
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constant pressure, but variable flow
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The pulmonary and systemic circuits are serviced by two pulsatile pumps that are set up in ______.
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The pulmonary and systemic circuits are serviced by two pulsatile pumps that are set up in series
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What is the benefit of the branching organization of the cardiovascular system - in particular what does this organization mean in terms of the organs being supplied with blood?
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The organs are set up in parallel. Think of it like a water company. Everyone (organ) receives fresh water (blood). Each person can also receive a variable amount of water (varied amount of blood to each organ)
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Unidirectional blood flow
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directionally imparted by valves
a. Valves function passively b. Ensure undirectionally |
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What ensures unidirectional blood flow in the blood vessels?
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valves that function passively.
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Cardiovascular system:
Compliant |
Compliant – relates to the ease and distensibility of a structure. How easy is it to push a large amount of blood into this structure
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Constant pressure and variable bloods supply provides _________ _________ blood flow.
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continuous peripheral blood flow
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Typical Aortic pressure:
Typical Pulmonary Artery Pressure: |
Aortic Pressure: 120/80
Pulmonary Artery Pressure 25/15 |
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Role
Arteriole |
RESISTANCE
important in controlling blood flow to the tissues by exchanging bloods with capillaries, they offer the highest resistance. |
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Role
Capillaries |
EXCHANGE
are much smaller than arterioles but there so many more that their net resistance is lower than in the arterioles. Exchange occurs here |
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Role
Venules |
EXCHANGE
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Role
Arteries |
CONDUIT
are conduit vessels because they offer a rapid and low resistance pathway to the organs with very little pressure loss |
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Role
Veins |
CAPACITANCE b/c Highly compliant
are called capacitance (2/3 to ¾ of the total volume) and are compliant so they hold most of the blood volume at any one time. Compliant – relates to the ease and distensibility of a structure. How easy is it to push a large amount of blood into this structure |
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Vessel characteristics as they relate to resistance...
1.) Caliber 2.) Number of vessels |
1.) Caliber – big vessels less resistance, small vessels large resistant
2.) How many vessels are there. More = lower resistance |
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Why is the resistance of capillaries smaller than arterioles?
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Despite the fact that arterioles are larger than capillaries there are FAR MORE CAPILLARIES than arterioles, which = lower resistance in capillaries
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What are the basic functions of the Kidneys?
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1.) HOH excretion – body volume regulation
2.) Salt excretion 3.) Excretion of Metabolic wastes – nitrogenous waste and drugs 4.) Acid-base regulation 5.) Endocrine function: a. Renin – Enzyme that forms angiotensin b. Erythropoietin – hormone stimulates RBC production c. 1,25-dihydroxyvitamin D |
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What are the Endocrine functions (3) of the Kidneys?
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Endocrine function:
a. Renin – Enzyme that forms angiotensin b. Erythropoietin – hormone stimulates RBC production c. 1,25-dihydroxyvitamin D |
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How does the heart respond to neural, hormonal and local feedback?
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Through
- Blood Volume - Blood Pressure - Blood Chemical Sensors |
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How do the Kidneys respond to neural, hormonal and local feedback?
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- Reduce/Conserve blood volume
- Excrete/Conserve plasma electrolytes |
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Ventricular Ejections
Describe Right ventricular ejection in terms of changes to walls and movements. |
o Shortening of the free wall
o Compression of the chamber (bellows action) |
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Ventricular Ejections
Describe left ventricular ejection in terms of contraction. What effect does this have on the RV |
o Contraction reduces the diameter of the ventricular chamber and tends to shorten base to apex length of the ventricle.
o Causes a “right ventricular assist”, which reduces the volume in RV chamber Thus the RV can tolerate an infarct because of this assist |
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Ventricular Ejections
“right ventricular assist” is caused by what? |
Contraction of the left ventricle
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T/F The left ventricle has a thicker wall than the right ventricle.
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True
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T/F The left ventricle has a circular shape
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True
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What is the ventricular myocardium composed of?
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It is composed of oblique and horizontal spiral muscles
These shorten the circumference (inner diameter) and long axis of the ventricle upon contraction. |
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Papillary muscles ensure that the ventricles contract _______.
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simultaneously
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What are the two semilunar valves and what structures are they between?
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Pulmonic valve -> lungs to LA
Aortic Valve -> Tissue to RA |
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T/F Major coronary arteries lie on the surface and go into smaller arterioles into the heart
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True
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Heart contractions can _____ coronary blood flow. Constrictions of muscles generally _____ their own blood flow.
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impede
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Subsystems of the Heart
what are the 5 subsystems? |
1.)Electrical conduction system
2.)Autonomic Nervous System 3.)Cardiac muscles 4.)Heart Valves 5.)Coronary circulation |
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Subsystems of the Heart
Electrical conduction system - what's the order? |
SA and AV nodes; bundle of His, Purkinje Fibers
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Subsystems of the Heart
Autonomic Nervous System 1.) Two systems 2.) _______ innervations of ventricular cells has great effect on the myocardium |
1. Sympathetic and Parasympathetic innervations
2. Sympathetic |
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Subsystems of the Heart
Cardiac muscles are called |
myocardium
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Subsystems of the Heart
Heart Valves: 2 main types |
Atrioventricular and semilunar valves
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What are the two AV valves and what structures do they connect?
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Tricuspid Valve: RA -> RV
Mitral (Bicuspid) Valve: LA->LV |
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What functional purpose do the papillary muscles and chordeae tendinaea serve?
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PREVENT EVERSION OFBLOOD from ventricles to atria
The function of the (Tricuspid valve RA->RV) Chordeae Tendinaea and (Mitral- Bicuspid valve LA->LV – also have CT) Papillary muscle is to prevent eversion of blood from the ventricles back into the atrial chambers |